Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
TonB C-terminal domain-containing protein
Resolvase/invertase-type recombinase catalytic
Polymerase/histidinol phosphatase N-terminal
Tryptophan synthase beta chain-like PALP
L,D-transpeptidase catalytic domain-containing protein
Major facilitator superfamily (MFS) profile
Interaction with polymerase core subunit RpoC
Glycine cleavage T-protein C-terminal barrel
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Aminoacyl-transfer RNA synthetases class-II family profile
Alanyl-transfer RNA synthetases family profile
RNA polymerase sigma factor 70 region 4 type 2
SUF system FeS cluster assembly SufBD N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Extensin-like C-terminal domain-containing protein
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Reversibly protonated during proton transport
RND efflux pump membrane fusion protein barrel-sandwich
Polysaccharide biosynthesis protein C-terminal
Probable periplasmic serine endoprotease DegP-like
UDP N-acetylglucosamine O-acyltransferase C-terminal
6-phosphogluconate dehydrogenase C-terminal
Flagellar basal body rod protein N-terminal
Prepilin type IV endopeptidase peptidase
NIF system FeS cluster assembly NifU N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Nitrogenase molybdenum-iron protein beta chain N-terminal
Spore coat protein U domain-containing protein
Heme-copper oxidase subunit III family profile
UDP-glucose/GDP-mannose dehydrogenase C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Transglycosylase SLT domain-containing protein
N,N-dimethylformamidase beta subunit-like C-terminal
Proline utilization A proline dehydrogenase N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
DNA mismatch repair proteins mutS family
Bacterial bifunctional deaminase-reductase C-terminal
Outer membrane protein assembly factor BamA
Glycosyltransferase subfamily 4-like N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Flagellar basal-body/hook protein C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Flagellar motor switch protein FliN-like C-terminal
Phosphogluconate dehydrogenase (decarboxylating) C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19
Large ribosomal subunit protein uL6 alpha-beta
Thiamin pyrophosphokinase thiamin-binding
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Transcription regulator AsnC/Lrp ligand binding
Penicillin-binding protein transpeptidase
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Cytochrome oxidase subunit II copper A binding
Lysozyme inhibitor LprI N-terminal domain-containing protein
Peptide methionine sulphoxide reductase MsrA
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Antitoxin Xre/MbcA/ParS-like toxin-binding
Peptidase S9 prolyl oligopeptidase catalytic
Glucose-methanol-choline oxidoreductase C-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Phosphoribosylformylglycinamidine synthase linker
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Molybdopterin cofactor biosynthesis C (MoaC)
Schiff-base intermediate with dihydroxyacetone-P
Putative Flp pilus-assembly TadG-like N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Signal transduction histidine kinase HWE region
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
TRAP C4-dicarboxylate transport system permease DctM subunit
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Could play a key role in the communication between the regulatory and the substrate sites
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Polysaccharide chain length determinant N-terminal
Methylaspartate ammonia-lyase C-terminal
Methylaspartate ammonia-lyase N-terminal
Lipoprotein-anchoring transpeptidase ErfK/SrfK
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Activator of Hsp90 ATPase homologue 1-like C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
O-(3'-phospho-DNA)-tyrosine intermediate
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Small ribosomal subunit protein uS4 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
DNA-directed DNA polymerase family A palm
CD-NTase-associated protein 12/Pycsar effector protein TIR
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Pyridoxamine 5'-phosphate oxidase putative
ABC-type glycine betaine transport system substrate-binding
Anti-bacteriophage protein A/HamA C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Could be important to modulate the pK values of the two catalytic cysteine residues
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Tetratricopeptide repeat-containing protein
Poly-beta-hydroxybutyrate polymerase N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Organic solvent tolerance-like N-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Membrane-bound lysozyme-inhibitor of c-type lysozyme
ABC transporter substrate-binding protein PnrA-like
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Essential for prephenate dehydratase activity
Glutamate synthase alpha subunit C-terminal
YMGG-like Gly-zipper domain-containing protein
Phosphotransferase system enzyme I N-terminal
Pseudouridine synthase I TruA alpha/beta
Alpha-glycerophosphate oxidase C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Ribose-phosphate pyrophosphokinase N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Membrane fusion protein biotin-lipoyl like
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Histidine phosphotransferase ChpT C-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Plays an important role in substrate specificity
Septum formation inhibitor MinC C-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Bacterial type II secretion system protein E
Inosine/uridine-preferring nucleoside hydrolase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Cytochrome oxidase subunit II transmembrane region profile
Schiff-base intermediate with acetoacetate
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Nitrile hydratase alpha /Thiocyanate hydrolase gamma
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Cytochrome b561 bacterial/Ni-hydrogenase
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Major facilitator superfamily associated
Adaptive response protein AidB N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Flagellar hook-length control protein-like C-terminal
Spore coat protein U (SCPU) domain-containing protein
Outer membrane lipoprotein omp10 homolog
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Pilus formation protein N-terminal domain-containing protein
Tetrahydrodipicolinate-N-succinyltransferase chain A
Release factor glutamine methyltransferase N-terminal
Peptidase M17 leucyl aminopeptidase N-terminal
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Large ribosomal subunit protein uL15/eL18
Survival protein SurE-like phosphatase/nucleotidase
Chromosomal replication initiator protein DnaA
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Glycosyl transferase family 3 N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Gamma-butyrobetaine hydroxylase-like N-terminal
Important for interaction with partner proteins
Cytochrome c oxidase subunit IV bacterial aa3 type
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
PHA accumulation regulator DNA-binding N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
O-(5'-phospho-DNA)-tyrosine intermediate
Outer membrane protein assembly factor BamD
Endoribonuclease L-PSP/chorismate mutase-like
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
RNA 2-O ribose methyltransferase substrate binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Cobaltochelatase subunit CobS N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Peptidase M15A C-terminal domain-containing protein
Dinitrogenase iron-molybdenum cofactor biosynthesis
YbaK/aminoacyl-tRNA synthetase-associated
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Transposase IS116/IS110/IS902 C-terminal
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Vanillate O-demethylase oxygenase-like C-terminal catalytic
Biopterin-dependent aromatic amino acid hydroxylase family profile
Alpha-D-phosphohexomutase alpha/beta/alpha
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-96)
Methylene-tetrahydrofolate reductase C-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
N-end rule aminoacyl transferase C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
4'-phosphopantetheinyl transferase N-terminal
Translation elongation factor P/YeiP central
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Cytochrome C biogenesis protein transmembrane
Type II secretion system protein TadB-like N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Tricarboxylic transport membrane protein
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Tripartite-type tricarboxylate transporter, receptor component TctC
N-sulphoglucosamine sulphohydrolase C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Proton acceptor; for glutaminase activity
Outer membrane protein beta-barrel domain-containing protein
Thiol:disulfide interchange protein DsbD N-terminal
Important for beta-aspartyl-AMP intermediate formation
Prokaryotic-type class I peptide chain release factors
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Glycine zipper domain-containing protein
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Chromosomal replication initiator DnaA C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Beta-lactamase hydrolase-like protein phosphatase-like
Tat pathway signal sequence domain protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Cytochrome c-type biogenesis protein CcmF C-terminal
CagE TrbE VirB component of type IV transporter system central
Nuclear transport factor 2 family protein
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
DNA topoisomerase I catalytic core eukaryotic-type
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Interacts with tRNA; defines subfamily-specific binding signature
Exonuclease VII large subunit C-terminal
Mannose-6-phosphate isomerase type II C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Large ribosomal subunit protein uL2 C-terminal
MtN3 and saliva related transmembrane protein
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
5-glutamyl coenzyme A thioester intermediate
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
NADH:ubiquinone oxidoreductase 30kDa subunit
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Heat-inducible transcription repressor HrcA C-terminal
DNA replication/recombination mediator RecO N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Saccharopine dehydrogenase-like C-terminal
Methionyl-tRNA synthetase anticodon-binding
S-adenosyl-L-homocysteine hydrolase NAD binding
Cob(I)alamin adenosyltransferase N-terminal
Anthranilate synthase component I N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Thymidylate synthase/dCMP hydroxymethylase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
RNA binding; important for wobble base 34 recognition
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Leucine-binding protein domain-containing protein
S-adenosylmethionine-dependent methyltransferase