Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
DNA replication/recombination mediator RecO N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Exonuclease VII large subunit C-terminal
Thiamine pyrophosphate enzyme TPP-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Nitrite/Sulfite reductase ferredoxin-like
Polysaccharide chain length determinant N-terminal
Cytochrome c-552/4 domain-containing protein
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Periplasmic nitrate reductase, electron transfer subunit
Thiamine pyrophosphate enzyme N-terminal TPP-binding
NarX-like N-terminal domain-containing protein
TRAP C4-dicarboxylate transport system permease DctM subunit
Lysozyme inhibitor LprI N-terminal domain-containing protein
Tryptophan synthase beta chain-like PALP
Choloylglycine hydrolase/NAAA C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Polymerase/histidinol phosphatase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Organic solvent tolerance-like N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
AMP-activated protein kinase glycogen-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Plasminogen-binding protein PgbA N-terminal
Plasminogen-binding protein PgbA N-terminal domain-containing protein
Ysc84 actin-binding domain-containing protein
Cytochrome b561 bacterial/Ni-hydrogenase
Ribonucleotide reductase large subunit C-terminal
Outer membrane porin F N-terminal domain-containing protein
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Glycosyl transferase family 3 N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Glycine zipper 2TM domain-containing protein
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Major facilitator superfamily (MFS) profile
Urease accessory protein UreH-like transmembrane
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Prokaryotic-type class I peptide chain release factors
RNA 2-O ribose methyltransferase substrate binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Large ribosomal subunit protein uL15/eL18
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Tat (Twin-arginine translocation) pathway signal sequence domain protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Aminoacyl-transfer RNA synthetases class-II family profile
Small ribosomal subunit protein uS4 N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Bacterial type II secretion system protein E
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Beta-lactamase hydrolase-like protein phosphatase-like
Involved in allosteric activation by GTP
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Pseudouridine synthase I TruA alpha/beta
Outer membrane protein beta-barrel domain-containing protein
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
NADH:ubiquinone oxidoreductase-like 20kDa subunit
TonB-dependent receptor-like beta-barrel
Alpha-amylase/4-alpha-glucanotransferase C-terminal
Alpha-amylase/4-alpha-glucanotransferase central
Glycoside hydrolase family 57 N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Essential for prephenate dehydratase activity
Major facilitator superfamily associated
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
NADH:ubiquinone oxidoreductase 30kDa subunit
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Resolvase/invertase-type recombinase catalytic
Important for interaction with partner proteins
Type II restriction enzyme and methyltransferase RM.Eco57I-like
ABC-type transport auxiliary lipoprotein component
Large ribosomal subunit protein uL2 C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Aminoacyl-tRNA synthetase class I anticodon-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
UDP-N-acetylenolpyruvoylglucosamine reductase C-terminal
Cation-transporting P-type ATPase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
UDP N-acetylglucosamine O-acyltransferase C-terminal
Carboxypeptidase regulatory-like domain-containing protein
Nitric oxide-responding transcriptional regulator Dnr (Crp/Fnr family)
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Sodium/calcium exchanger membrane region
Carbamoyl-phosphate synthase small subunit N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Peptidase S9 prolyl oligopeptidase catalytic
Penicillin-binding protein transpeptidase
Cytochrome C biogenesis protein transmembrane
NIF system FeS cluster assembly NifU C-terminal
Damage-control phosphatase ARMT1-like metal-binding
Pyruvate phosphate dikinase AMP/ATP-binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Cytochrome oxidase subunit II copper A binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Type II secretion system protein GspG C-terminal
Translation elongation factor P/YeiP central
DNA-directed DNA polymerase family A palm
NIF system FeS cluster assembly NifU N-terminal
Putative exodeoxyribonuclease 8 PDDEXK-like
Shikimate dehydrogenase substrate binding N-terminal
Prepilin type IV endopeptidase peptidase
Phosphoribosylformylglycinamidine synthase linker
Thioredoxin-like fold domain-containing protein
O-(5'-phospho-DNA)-tyrosine intermediate
Saccharopine dehydrogenase-like C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Predicted DNA-binding protein ribbon-helix-helix
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Proton acceptor; for glutaminase activity
Cysteine sulfenic acid (-SOH) intermediate
Mannose-6-phosphate isomerase type II C-terminal
Alanyl-transfer RNA synthetases family profile
Dinitrogenase iron-molybdenum cofactor biosynthesis
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-96)
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Glycoside-hydrolase family GH114 TIM-barrel
DNA mismatch repair proteins mutS family
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Involved in ionization of N3 of dUMP, leading to its activation
ATP synthase F1 complex delta/epsilon subunit N-terminal
Bacteriophage lambda Replication protein O N-terminal
Ribosomal RNA small subunit methyltransferase E methyltransferase
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Sugar fermentation stimulation protein C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Aconitase A/isopropylmalate dehydratase small subunit swivel
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Schiff-base intermediate with substrate; via pyruvic acid
Reversibly protonated during proton transport
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
RNA binding; important for wobble base 34 recognition
Release factor glutamine methyltransferase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Metallo-beta-lactamase domain-containing protein
ATP-dependent DNA helicase RecG C-terminal
RlpA-like protein double-psi beta-barrel
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Periplasmic copper-binding protein NosD beta helix
Peptide methionine sulphoxide reductase MsrA
N6 adenine-specific DNA methyltransferase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
SUF system FeS cluster assembly SufBD N-terminal
Polysaccharide biosynthesis protein CapD-like
ATP-grasp fold succinyl-CoA synthetase-type
Plays an important role in substrate specificity
Interaction with polymerase core subunit RpoC
Schiff-base intermediate with dihydroxyacetone-P
Survival protein SurE-like phosphatase/nucleotidase
Membrane fusion protein biotin-lipoyl like
Chromosomal replication initiator DnaA C-terminal
Important for beta-aspartyl-AMP intermediate formation
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding