2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Major facilitator superfamily (MFS) profile
Putative Flp pilus-assembly TadG-like N-terminal
Polysaccharide chain length determinant N-terminal
Peptidase M15C domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Glycosyltransferase subfamily 4-like N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
RNA polymerase sigma factor 70 region 4 type 2
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Flagellar motor switch protein FliN-like C-terminal
Exonuclease VII large subunit C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Peptidase MA-like domain-containing protein
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Glutathionylspermidine synthase pre-ATP-grasp-like
Glycosyl transferase family 3 N-terminal
Prokaryotic-type class I peptide chain release factors
Pyruvate phosphate dikinase AMP/ATP-binding
Tryptophan synthase beta chain-like PALP
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Reversibly protonated during proton transport
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
YbaK/aminoacyl-tRNA synthetase-associated
Pyridoxamine 5'-phosphate oxidase putative
Proton-translocating ferredoxin:NAD(+) oxidoreductase complex subunit B
Bacterial type II secretion system protein E
Phosphomannose isomerase type I catalytic
Large ribosomal subunit protein uL15/eL18
Phosphoribosylformylglycinamidine synthase linker
O-(5'-phospho-DNA)-tyrosine intermediate
Phosphatidic acid phosphatase type 2/haloperoxidase
Aminoacyl-transfer RNA synthetases class-II family profile
Alpha-D-phosphohexomutase alpha/beta/alpha
Sugar fermentation stimulation protein C-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Cation-transporting P-type ATPase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
CobB/CobQ-like glutamine amidotransferase
Prepilin type IV endopeptidase peptidase
3-beta hydroxysteroid dehydrogenase/isomerase
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
ABC transporter substrate-binding protein PnrA-like
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Anthranilate synthase component I N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Essential for prephenate dehydratase activity
Transposase IS116/IS110/IS902 C-terminal
DNA mismatch repair proteins mutS family
Polymerase/histidinol phosphatase N-terminal
Proton-translocating ferredoxin:NAD(+) oxidoreductase complex subunit A
Ribose-phosphate pyrophosphokinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
HicB-like antitoxin of toxin-antitoxin system
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Increases nucleophilicity of active site Cys
Bacterial transcription activator effector binding
Schiff-base intermediate with acetaldehyde
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Thiamin pyrophosphokinase thiamin-binding
Important for beta-aspartyl-AMP intermediate formation
Superoxide dismutase copper/zinc binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Release factor glutamine methyltransferase N-terminal
O-(phosphoribosyl dephospho-coenzyme A)serine
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Mannose-6-phosphate isomerase type II C-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Mandelate racemase/muconate lactonizing enzyme C-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Membrane fusion protein biotin-lipoyl like
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Aspartate/homoserine dehydrogenase NAD-binding
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Membrane insertase YidC/Oxa/ALB C-terminal
Penicillin-binding protein transpeptidase
DNA-directed DNA polymerase family A palm
Chromosomal replication initiator DnaA C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Dinitrogenase iron-molybdenum cofactor biosynthesis
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
PrcB C-terminal domain-containing protein
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Sodium/calcium exchanger membrane region
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease 3
Shikimate dehydrogenase substrate binding N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Threonine/serine exporter-like N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Polysaccharide biosynthesis protein C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Proton-translocating ferredoxin:NAD(+) oxidoreductase complex subunit E
Molybdopterin cofactor biosynthesis C (MoaC)
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Glycosyltransferase family 28 N-terminal
RNA 2-O ribose methyltransferase substrate binding
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Carbamoyl-phosphate synthase small subunit N-terminal
Glycine cleavage T-protein C-terminal barrel
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
Flagellar hook-length control protein-like C-terminal
Heat-inducible transcription repressor HrcA C-terminal
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Peptidase S9 prolyl oligopeptidase catalytic
Sporulation stage II protein D amidase enhancer LytB N-terminal
Polysaccharide biosynthesis protein CapD-like
Proton-translocating ferredoxin:NAD(+) oxidoreductase complex subunit C
Terminase large subunit gp17-like C-terminal
6-phosphogluconate dehydrogenase C-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Alanyl-transfer RNA synthetases family profile
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Type III secretion system flagellar brake protein YcgR PilZN
Aldehyde ferredoxin oxidoreductase N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Succinate dehydogenase/fumarate reductase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Methylaspartate ammonia-lyase C-terminal
Methylaspartate ammonia-lyase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Pseudouridine synthase I TruA alpha/beta
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Phosphotransferase system enzyme I N-terminal
Urease accessory protein UreH-like transmembrane
NADH-rubredoxin oxidoreductase C-terminal
ATP-dependent DNA helicase RecG C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Membrane protein 6-pyruvoyl-tetrahydropterin synthase-related
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Large ribosomal subunit protein uL2 C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Tail specific protease domain-containing protein
Proton-translocating ferredoxin:NAD(+) oxidoreductase complex subunit G
Resolvase/invertase-type recombinase catalytic
Formylmethanofuran dehydrogenase subunit E
Positions MEP for the nucleophilic attack
Plays an important role in substrate specificity
Transcriptional coactivator p15 (PC4) C-terminal
BREX system Lon protease-like BrxL N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
General stress protein FMN-binding split barrel
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Schiff-base intermediate with D-ribose 5-phosphate
Aminoacyl-tRNA synthetase class I anticodon-binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Peptidoglycan recognition protein family
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
DNA replication/recombination mediator RecO N-terminal
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Sporulation transcription regulator WhiA N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Involved in allosteric activation by GTP
ATP synthase F1 complex delta/epsilon subunit N-terminal
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Type I restriction modification DNA specificity
CO dehydrogenase/acetyl-CoA synthase delta subunit TIM barrel
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Survival protein SurE-like phosphatase/nucleotidase
Terminase large subunit-like endonuclease
Small ribosomal subunit protein uS4 N-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Sporulation stage IV protein A C-terminal
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
DNA polymerase III delta subunit C-terminal
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Carbon monoxide dehydrogenase subunit alpha ,N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Gly-cisPro motif, important for rejection of L-amino acids
Helix-hairpin-helix DNA-binding motif class 1
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
RNA binding; important for wobble base 34 recognition
Proton-translocating ferredoxin:NAD(+) oxidoreductase complex subunit D
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Ribosomal RNA adenine methylase transferase N-terminal
Septum formation inhibitor MinC C-terminal
Bacterial extracellular solute-binding protein
Methylene-tetrahydrofolate reductase C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type