S-adenosylmethionine-dependent methyltransferase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Homocysteine biosynthesis enzyme sulfur-incorporation
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Proton acceptor; for glutaminase activity
Tryptophan synthase beta chain-like PALP
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Schiff-base intermediate with D-ribose 5-phosphate
Major facilitator superfamily (MFS) profile
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Important for substrate specificity; cannot use PPi as phosphoryl donor
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Large ribosomal subunit protein uL15/eL18
Polymerase/histidinol phosphatase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
ATPsynthase alpha/beta subunit N-terminal extension
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
ABC transporter substrate-binding protein PnrA-like
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
TonB-dependent receptor-like beta-barrel
TonB-dependent receptor-like beta-barrel domain-containing protein
Alpha-amylase/4-alpha-glucanotransferase C-terminal
Alpha-amylase/4-alpha-glucanotransferase central
Glycoside hydrolase family 57 N-terminal
Peptidase MA-like domain-containing protein
Leucine-rich repeat domain-containing protein
Polysaccharide biosynthesis protein CapD-like
Aminoacyl-transfer RNA synthetases class-II family profile
O-(5'-phospho-DNA)-tyrosine intermediate
YbaK/aminoacyl-tRNA synthetase-associated
Pyruvate/ketoisovalerate oxidoreductase catalytic
Glycine cleavage T-protein C-terminal barrel
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large ribosomal subunit protein uL2 C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Solute-binding protein family 3/N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Putative regulatory protein FmdB Zinc ribbon
6-hydroxymethylpterin diphosphokinase MptE-like
Glycosyltransferase subfamily 4-like N-terminal
Small ribosomal subunit protein uS4 N-terminal
Flagellar motor switch protein FliN-like C-terminal
Type I restriction modification DNA specificity
Membrane insertase YidC/Oxa/ALB C-terminal
Membrane fusion protein biotin-lipoyl like
RND efflux pump membrane fusion protein barrel-sandwich
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
D-galactose/methyl-galactoside binding periplasmic protein MglB
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
RNA 2-O ribose methyltransferase substrate binding
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Pyrimidine nucleoside phosphorylase C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Signal transduction histidine kinase 5TM receptor LytS transmembrane region
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Flagellar Assembly Protein A N-terminal region
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Glycoside hydrolase family 31 N-terminal
Outer membrane protein beta-barrel domain-containing protein
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
HicB-like antitoxin of toxin-antitoxin system
Restriction system protein Mrr-like N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Alpha-D-phosphohexomutase alpha/beta/alpha
Chromosomal replication initiator DnaA C-terminal
DNA-directed DNA polymerase family A palm
Flagellar assembly protein FliH/Type III secretion system HrpE
General stress protein FMN-binding split barrel
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Flagellar hook-length control protein-like C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Ribosomal RNA small subunit methyltransferase E methyltransferase
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
DNA mismatch repair proteins mutS family
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Phosphomannose isomerase type I catalytic
Arginine decarboxylase C-terminal helical
Penicillin-binding protein transpeptidase
Pseudouridine synthase I TruA alpha/beta
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Prokaryotic-type class I peptide chain release factors
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Bacterial bifunctional deaminase-reductase C-terminal
RNA binding; important for wobble base 34 recognition
Cation-transporting P-type ATPase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
2-oxoacid dehydrogenase acyltransferase catalytic
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Outer membrane lipoprotein-sorting protein
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
AMP-activated protein kinase glycogen-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
RNA polymerase sigma factor 70 region 4 type 2
Phosphoribosylformylglycinamidine synthase linker
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Translation elongation factor P/YeiP central
TRAP C4-dicarboxylate transport system permease DctM subunit
Threonine/serine exporter-like N-terminal
Plays an important role in discriminating NADH against NADPH
Transcriptional coactivator p15 (PC4) C-terminal
Outer membrane lipoprotein BamD-like domain-containing protein
Type III secretion system flagellar brake protein YcgR PilZN
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Interaction with polymerase core subunit RpoC
Glycoside hydrolase family 42 N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Alanyl-transfer RNA synthetases family profile
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Anthranilate synthase component I N-terminal
Signal transduction histidine kinase HWE region
Phosphatidic acid phosphatase type 2/haloperoxidase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Ribosome maturation factor RimP N-terminal
Interchain (with Cys-211); in linked form
Interchain (with Cys-51); in linked form
Involved in ionization of N3 of dUMP, leading to its activation
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Water stress and hypersensitive response
Ribosomal RNA small subunit methyltransferase E PUA-like
Glucosamine/galactosamine-6-phosphate isomerase
NfeD-like C-terminal domain-containing protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
ABC transporter substrate-binding protein
Plays an important role in substrate specificity
Cell envelope-related transcriptional attenuator
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Inner membrane protein YgaP-like transmembrane
ABC-type uncharacterised transport system
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
DNA replication/recombination mediator RecO N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
NIF system FeS cluster assembly NifU N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
1,4-alpha-glucan branching enzyme C-terminal
NIF system FeS cluster assembly NifU C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
O-(3'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Glycosyl hydrolase family 30 beta sandwich
Glucose-6-phosphate isomerase prokaryote
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glycosyl transferase family 3 N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
6-phosphogluconate dehydrogenase C-terminal
Methylaspartate ammonia-lyase C-terminal
Methylaspartate ammonia-lyase N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
N6 adenine-specific DNA methyltransferase N-terminal
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Ionotropic glutamate receptor C-terminal
Release factor glutamine methyltransferase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Cytochrome C biogenesis protein transmembrane
Cytochrome C biogenesis protein transmembrane domain-containing protein
Peptide methionine sulfoxide reductase MsrB
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Schiff-base intermediate with acetaldehyde
Phosphotransferase system enzyme I N-terminal