Polysaccharide chain length determinant N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Phosphoadenosine phosphosulphate reductase
N-end rule aminoacyl transferase C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Anthranilate synthase component I N-terminal
Helix-hairpin-helix DNA-binding motif class 1
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Peptidase S9 prolyl oligopeptidase catalytic
Cytochrome c-type biogenesis protein CcmF C-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Exonuclease VII large subunit C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Alpha-L-glutamate ligase-related protein ATP-grasp
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Polymerase/histidinol phosphatase N-terminal
Tryptophan synthase beta chain-like PALP
Alpha-D-phosphohexomutase alpha/beta/alpha
Proline utilization A proline dehydrogenase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Major facilitator superfamily (MFS) profile
Required for zinc-mediated homotetramerization and catalytic activity
Quercetin 2,3-dioxygenase C-terminal cupin
Solute-binding protein family 3/N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Flagellar hook-length control protein-like C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
For 3-hydroxyacyl-CoA dehydrogenase activity
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
DNA mismatch repair proteins mutS family
Pyrroline-5-carboxylate reductase catalytic N-terminal
Flagellar motor switch protein FliN-like C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Aminoacyl-transfer RNA synthetases class-II family profile
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Arginine decarboxylase C-terminal helical
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Interaction with polymerase core subunit RpoC
Acyl-CoA dehydrogenase C-terminal bacterial-type
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Phosphoethanolamine transferase N-terminal
Major facilitator superfamily associated
Phosphocysteine intermediate; for EIIB activity
DNA-directed DNA polymerase family A palm
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Aldehyde oxidase/xanthine dehydrogenase first molybdopterin binding
Aldehyde oxidase/xanthine dehydrogenase second molybdopterin binding
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Homogentisate 1,2-dioxygenase N-terminal
Resolvase/invertase-type recombinase catalytic
Threonine/serine exporter-like N-terminal
Ionotropic glutamate receptor C-terminal
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Transcriptional regulator SgrR N-terminal HTH
Membrane fusion protein biotin-lipoyl like
Electron transfer via tryptophanyl radical
Sodium/calcium exchanger membrane region
Integral membrane protein YccS N-terminal
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Peptide methionine sulphoxide reductase MsrA
S-adenosyl-L-homocysteine hydrolase NAD binding
Bacterial type II secretion system protein E
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Aspartate/homoserine dehydrogenase NAD-binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Outer membrane protein assembly factor BamB
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Inosine/uridine-preferring nucleoside hydrolase
N6 adenine-specific DNA methyltransferase N-terminal
Transglutaminase domain-containing protein
Type II secretion system protein GspG C-terminal
TonB-dependent receptor-like beta-barrel
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Small ribosomal subunit protein uS4 N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Release factor glutamine methyltransferase N-terminal
Proton acceptor; for glutaminase activity
Could play a key role in the communication between the regulatory and the substrate sites
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Reversibly protonated during proton transport
O-(3'-phospho-DNA)-tyrosine intermediate
YbaK/aminoacyl-tRNA synthetase-associated
Thiol:disulfide interchange protein DsbD
O-(5'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein uL15/eL18
Haem-binding uptake Tiki superfamily ChaN
Mannose-6-phosphate isomerase type II C-terminal
Ribonucleotide reductase large subunit C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Protein-tyrosine phosphatase YopH N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Mandelate racemase/muconate lactonizing enzyme C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
NIF system FeS cluster assembly NifU N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Negative modulator of initiation of replication SeqA N-terminal
Replication modulator SeqA C-terminal DNA-binding
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
ABC-type transport auxiliary lipoprotein component
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Poly-beta-hydroxybutyrate polymerase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
TRAP C4-dicarboxylate transport system permease DctM subunit
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Pyridine nucleotide-disulphide oxidoreductase dimerisation
DNA polymerase III subunit delta C-terminal
Polysaccharide biosynthesis protein CapD-like
Tetrahydrodipicolinate-N-succinyltransferase chain A
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Heme-copper oxidase subunit III family profile
Phosphatidic acid phosphatase type 2/haloperoxidase
Flagellar assembly protein FliH/Type III secretion system HrpE
Prepilin type IV endopeptidase peptidase
Putative auto-transporter adhesin head GIN
Glycosyl transferase family 3 N-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
PliI/PliC-like inhibitor of I-type lysozyme
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Amino acid ABC transporter substrate-binding protein
Membrane insertase YidC/Oxa/ALB C-terminal
Important for substrate binding and specificity
Outer membrane protein beta-barrel domain-containing protein
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
ABC transporter substrate-binding protein PnrA-like
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Pyruvate phosphate dikinase AMP/ATP-binding
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Lytic transglycosylase superhelical linker
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Yop protein translocation protein D periplasmic
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Nitrite/Sulfite reductase ferredoxin-like
Phosphatidylglycerol lysyltransferase C-terminal
4'-phosphopantetheinyl transferase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Hypersensitivity response secretion-like HrpJ
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Appears to be important in orienting the phosphate for catalysis
ASP external chaperone domain-containing protein
Pyrimidine nucleoside phosphorylase C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Involved in tetramerization or stability of the tetramer
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Erythronate-4-phosphate dehydrogenase dimerisation
Ribose-phosphate pyrophosphokinase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Penicillin-binding protein transpeptidase
Carbamoyl-phosphate synthase small subunit N-terminal
Bacterial transcription activator effector binding
Periplasmic nitrate reductase, electron transfer subunit
Ionotropic glutamate receptor L-glutamate and glycine-binding
Urease accessory protein UreH-like transmembrane
Nucleophile; cysteine thiosulfonate intermediate
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Ribosomal RNA adenine methylase transferase N-terminal
Phosphomannose isomerase type I catalytic
Phosphomannose isomerase type I helical insertion
Bacterial virulence factor lipase N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Pseudouridine synthase I TruA alpha/beta
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Large ribosomal subunit protein uL2 C-terminal
RNA binding; important for wobble base 34 recognition
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Prokaryotic-type class I peptide chain release factors
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
NIF system FeS cluster assembly NifU C-terminal
Sugar fermentation stimulation protein C-terminal
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Chromosome partition protein MukF C-terminal
Chromosome partition protein MukF middle
Chromosome partition protein MukF winged-helix
Alpha-glycerophosphate oxidase C-terminal
Pyrroline-5-carboxylate reductase dimerisation
Beta-hexosaminidase bacterial type N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Phosphotransferase system enzyme I N-terminal
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
DNA replication/recombination mediator RecO N-terminal
6-hydroxymethylpterin diphosphokinase MptE-like
Outer membrane protein assembly factor BamA
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Bacterial bifunctional deaminase-reductase C-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Organic solvent tolerance-like N-terminal
Formate-dependent nitrite reductase complex subunit
Translation elongation factor P/YeiP central
Cysteine sulfenic acid (-SOH) intermediate
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Important for interaction with partner proteins
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Replication initiation protein-like C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Chitobiase/beta-hexosaminidases N-terminal
Important for beta-aspartyl-AMP intermediate formation
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Aminoacyl-tRNA synthetase class I anticodon-binding
Plays an important role in discriminating NADH against NADPH
Outer-membrane lipoprotein carrier protein
Pyruvate dehydrogenase E1 component middle
Type III secretion system effector delivery regulator TyeA
Mechanosensitive ion channel inner membrane
Schiff-base intermediate with acetaldehyde
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Interacts with tRNA; defines subfamily-specific binding signature
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
D-galactose/methyl-galactoside binding periplasmic protein MglB
Survival protein SurE-like phosphatase/nucleotidase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Autotransporter domain-containing protein
Biopterin-dependent aromatic amino acid hydroxylase family profile
ATP synthase F1 complex delta/epsilon subunit N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Large ribosomal subunit protein uL6 alpha-beta
Large ribosomal subunit protein bL25 L25
RNA methyltransferase SpoU/TrmH type C-terminal
Plays an important role in substrate specificity
ABC-type glycine betaine transport system substrate-binding
Outer membrane lipoprotein-sorting protein
NlpE C-terminal OB domain-containing protein
Transcription elongation factor GreA/GreB N-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-91)
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Alanyl-transfer RNA synthetases family profile
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Involved in allosteric activation by GTP
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Glycine cleavage T-protein C-terminal barrel
RNA 2-O ribose methyltransferase substrate binding
NADH-rubredoxin oxidoreductase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal