NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Hypersensitivity response secretion-like HrpJ
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Outer membrane protein beta-barrel domain-containing protein
Membrane lipoprotein lipid attachment site
Large ribosomal subunit protein uL2 C-terminal
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Peptide methionine sulphoxide reductase MsrA
Anti-bacteriophage protein A/HamA C-terminal
CD-NTase associated protein 4-like DNA endonuclease
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Schiff-base intermediate with substrate; via pyruvic acid
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Transcriptional regulator AbiEi antitoxin N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Translation elongation factor P/YeiP central
Translation elongation factor EFTs/EF1B dimerisation
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Helix-hairpin-helix DNA-binding motif class 1
RND efflux pump membrane fusion protein barrel-sandwich
TRAP C4-dicarboxylate transport system permease DctM subunit
Transposase IS116/IS110/IS902 C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Reversibly protonated during proton transport
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Ribose-phosphate pyrophosphokinase N-terminal
Major facilitator superfamily (MFS) profile
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Non-canonical purine NTP phosphatase/PRRC1
Tryptophan synthase beta chain-like PALP
Oxidoreductase molybdopterin-binding domain-containing protein
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Sodium symporter small subunit predicted
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Mandelate racemase/muconate lactonizing enzyme C-terminal
Outer membrane protein assembly factor BamB
Cytochrome c-type biogenesis protein CcmF C-terminal
Plays an important role in discriminating NADH against NADPH
Gfo/Idh/MocA-like oxidoreductase N-terminal
Flagella basal body P-ring formation protein FlgA
Flagella basal body P-ring formation protein FlgA C-terminal
TonB-dependent receptor-like beta-barrel
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Mannose-6-phosphate isomerase type II C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Gfo/Idh/MocA-like oxidoreductase C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Right handed beta helix domain-containing protein
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Penicillin-binding protein transpeptidase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Exonuclease VII large subunit C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Required for zinc-mediated homotetramerization and catalytic activity
Glycoside-hydrolase family GH114 TIM-barrel
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Polymerase/histidinol phosphatase N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Flagellar motor switch protein FliN-like C-terminal
Phosphoadenosine phosphosulphate reductase
6-hydroxymethylpterin diphosphokinase MptE-like
Interaction with polymerase core subunit RpoC
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Peptidase S8/S53 domain-containing protein
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Bacterial type II secretion system protein E
O-(5'-phospho-DNA)-tyrosine intermediate
Type VI secretion system IcmF C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Peptide methionine sulfoxide reductase MsrA
DNA polymerase III subunit delta C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Flagellar hook-length control protein-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Beta-lactamase hydrolase-like protein phosphatase-like
Bacterial virulence factor lipase N-terminal
Survival protein SurE-like phosphatase/nucleotidase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Pseudouridine synthase I TruA alpha/beta
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Proton acceptor; for glutaminase activity
Gp5/Type VI secretion system Vgr protein OB-fold
ABC-type glycine betaine transport system substrate-binding
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Glycine cleavage T-protein C-terminal barrel
Thymidylate synthase/dCMP hydroxymethylase
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Interacts with tRNA; defines subfamily-specific binding signature
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Pyruvate dehydrogenase E1 component middle
PhoD-like phosphatase metallophosphatase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Disulphide bond isomerase DsbC/G N-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Outer membrane protein domain-containing protein
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Flagellar assembly protein FliH/Type III secretion system HrpE
Peptidase S9 prolyl oligopeptidase catalytic
Large ribosomal subunit protein uL15/eL18
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Prokaryotic-type class I peptide chain release factors
Anthranilate synthase component I N-terminal
Alpha-glycerophosphate oxidase C-terminal
Phosphogluconate dehydrogenase (decarboxylating) C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Important for interaction with partner proteins
Prepilin type IV endopeptidase peptidase
Major facilitator superfamily associated
AMP-activated protein kinase glycogen-binding
N-sulphoglucosamine sulphohydrolase C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-88)
Essential for prephenate dehydratase activity
4'-cysteinyl-tryptophylquinone (Cys-Trp)
Could play a key role in the communication between the regulatory and the substrate sites
Glycosyl transferase family 28 C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Alanyl-transfer RNA synthetases family profile
Shikimate dehydrogenase substrate binding N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Heme-copper oxidase subunit III family profile
Polysaccharide biosynthesis protein CapD-like
Aconitase A/isopropylmalate dehydratase small subunit swivel
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Arginine decarboxylase C-terminal helical
Large ribosomal subunit protein uL30-like ferredoxin-like fold
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
5-glutamyl coenzyme A thioester intermediate
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Type II secretion system protein GspI C-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Surface lipoprotein of Spirochaetales order
4'-phosphopantetheinyl transferase N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Could be important to modulate the pK values of the two catalytic cysteine residues
Seems to be a necessary countercharge to the potassium cations
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Glycosyl transferase family 3 N-terminal
DNA mismatch repair proteins mutS family
Plays an important role in substrate specificity
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Phosphorylase b kinase regulatory subunit alpha/beta C-terminal
Lipocalin-like domain-containing protein
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Pyrroline-5-carboxylate reductase dimerisation
NIF system FeS cluster assembly NifU C-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
ABC transporter substrate-binding protein PnrA-like
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Inosine/uridine-preferring nucleoside hydrolase
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
ABC transporter substrate-binding protein
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Rap1a immunity protein domain-containing protein
DNA-directed DNA polymerase family A palm
Glutamate synthase alpha subunit C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Lysidine-tRNA(Ile) synthetase C-terminal
Chromosome segregation ATPase-like protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Type III secretion system flagellar brake protein YcgR PilZN
HNH/Endo VII superfamily nuclease toxins
Glutathionylspermidine synthase pre-ATP-grasp-like
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
C-type lysozyme inhibitor domain-containing protein
Transglutaminase domain-containing protein
Leucine-binding protein domain-containing protein
Electron transfer via tryptophanyl radical
Yop protein translocation protein D periplasmic
Outer membrane protein assembly factor BamE
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase-like C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-106)
Solute-binding protein family 3/N-terminal domain-containing protein
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Microcin J25-processing protein McjB C-terminal
Release factor glutamine methyltransferase N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
DNA replication/recombination mediator RecO N-terminal
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Small ribosomal subunit protein uS4 N-terminal
Phosphoesterase PA-phosphatase related protein
6-phosphogluconate dehydrogenase C-terminal
ABC transporter substrate binding protein
Transcription elongation factor GreA/GreB C-terminal
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Tripartite tricarboxylate transporter (TTT) family, substrate binding protein
Fibrinogen C-terminal domain-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Gly-cisPro motif, important for rejection of L-amino acids
Sodium/calcium exchanger membrane region
Positions MEP for the nucleophilic attack
Important for substrate binding and specificity
Sugar fermentation stimulation protein C-terminal
Outer-membrane lipoprotein carrier protein
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
HicB-like antitoxin of toxin-antitoxin system
Serine aminopeptidase S33 domain-containing protein
UDP N-acetylglucosamine O-acyltransferase C-terminal
RNA 2-O ribose methyltransferase substrate binding
Chromosomal replication initiator DnaA C-terminal
CobB/CobQ-like glutamine amidotransferase
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Erythronate-4-phosphate dehydrogenase dimerisation
Bacterial transcription activator effector binding
Methylguanine DNA methyltransferase ribonuclease-like
Aromatic amino acid beta-eliminating lyase/threonine aldolase
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Signal transduction histidine kinase internal region
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Putative FAD-dependent oxidoreductase LodB
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
C4-dicarboxylate ABC transporter substrate-binding protein
SUF system FeS cluster assembly SufBD N-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Membrane insertase YidC/Oxa/ALB C-terminal
tRNA(Met) cytidine acetyltransferase TmcA N-terminal
Glycoside hydrolase 123 C-terminal domain-containing protein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Glycosyltransferase family 28 N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Membrane fusion protein biotin-lipoyl like
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
High potential iron-sulfur proteins family profile