DNA mismatch repair proteins mutS family
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Alanyl-transfer RNA synthetases family profile
Cysteine sulfenic acid (-SOH) intermediate
Adenosylcobalamin biosynthesis, GlcG-related protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
SUF system FeS cluster assembly SufBD N-terminal
Bacterial type II secretion system protein E
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Tryptophan synthase beta chain-like PALP
Tetrahydrodipicolinate-N-succinyltransferase chain A
tRNA pseudouridylate synthase B C-terminal
Outer-membrane lipoprotein carrier protein
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Type ISP restriction-modification enzyme LLaBIII C-terminal specificity
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Serine aminopeptidase S33 domain-containing protein
Major facilitator superfamily (MFS) profile
6-phosphogluconate dehydrogenase C-terminal
Exonuclease VII large subunit C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Calcium/calmodulin-dependent protein kinase II association-domain
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-96)
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Large ribosomal subunit protein uL15/eL18
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
O-(5'-phospho-DNA)-tyrosine intermediate
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Glycosyl transferase family 3 N-terminal
Large ribosomal subunit protein uL2 C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Moybdenum cofactor oxidoreductase dimerisation
Thiol:disulfide interchange protein DsbA
Polypeptide-transport-associated ShlB-type
Cation-transporting P-type ATPase N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Membrane insertase YidC/Oxa/ALB C-terminal
DNA replication/recombination mediator RecO N-terminal
Organic solvent tolerance-like N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Carbamoyl-phosphate synthase small subunit N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Ribose-phosphate pyrophosphokinase N-terminal
Interaction with polymerase core subunit RpoC
DNA-directed DNA polymerase family A palm
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Penicillin-binding protein transpeptidase
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Schiff-base intermediate with substrate; via pyruvic acid
TonB-dependent receptor-like beta-barrel
Alpha-D-phosphohexomutase alpha/beta/alpha
RNA 2-O ribose methyltransferase substrate binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
TRAP C4-dicarboxylate transport system permease DctM subunit
Pseudouridine synthase I TruA alpha/beta
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Ribulose bisphosphate carboxylase small subunit
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Chromosomal replication initiator protein DnaA
N6 adenine-specific DNA methyltransferase N-terminal
Polymerase/histidinol phosphatase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Lytic transglycosylase superhelical linker
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Required for dimer formation and molybdate binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
RNA binding; important for wobble base 34 recognition
Survival protein SurE-like phosphatase/nucleotidase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Pyruvate dehydrogenase E1 component middle
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Plays an important role in substrate specificity
Urease accessory protein UreH-like transmembrane
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Polysaccharide chain length determinant N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Probable peptidoglycan glycosyltransferase FtsW
Inner membrane protein YgaP-like transmembrane
Chalcone isomerase domain-containing protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
Quercetin 2,3-dioxygenase C-terminal cupin
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Type I restriction modification DNA specificity
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Translation elongation factor P/YeiP central
Outer membrane protein assembly factor BamA
Disulphide bond isomerase DsbC/G N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Outer membrane protein beta-barrel domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Transcriptional regulator AbiEi antitoxin N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Large ribosomal subunit protein uL6 alpha-beta
Important for substrate binding and specificity
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Na+/H+ antiporter MnhB subunit-related protein
Lysidine-tRNA(Ile) synthetase C-terminal
tRNA(Ile)-lysidine synthase substrate-binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
NAD(P)H-quinone oxidoreductase subunit 2 N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Erythronate-4-phosphate dehydrogenase dimerisation
Flavocytochrome c sulphide dehydrogenase flavin-binding
Membrane fusion protein biotin-lipoyl like
Membrane fusion protein biotin-lipoyl like domain-containing protein
Restriction endonuclease type IV Mrr domain-containing protein
Electron transfer via tryptophanyl radical
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Cell division protein FtsQ/DivIB C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Outer membrane protein assembly factor BamB
Type II secretion system protein GspG C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Small ribosomal subunit protein uS4 N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Ribosomal RNA adenine methylase transferase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Glucosamine/galactosamine-6-phosphate isomerase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Thioredoxin-like fold domain-containing protein
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
Solute-binding protein family 3/N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Prokaryotic-type class I peptide chain release factors
UDP N-acetylglucosamine O-acyltransferase C-terminal
Proton acceptor; for glutaminase activity