Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
NIF system FeS cluster assembly NifU C-terminal
SUF system FeS cluster assembly SufBD N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Peptidase S9 prolyl oligopeptidase catalytic
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Polymerase/histidinol phosphatase N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Major facilitator superfamily (MFS) profile
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Small ribosomal subunit protein uS4 N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Aminoacyl-transfer RNA synthetases class-II family profile
Anthranilate synthase component I N-terminal
Tryptophan synthase beta chain-like PALP
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Helix-hairpin-helix DNA-binding motif class 1
Ribosomal RNA adenine methylase transferase N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Sporulation transcription regulator WhiA N-terminal
Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Phosphatidic acid phosphatase type 2/haloperoxidase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Reversibly protonated during proton transport
Resolvase/invertase-type recombinase catalytic
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
PhoD-like phosphatase metallophosphatase
ABC transporter substrate-binding protein PnrA-like
Essential for prephenate dehydratase activity
Heat-inducible transcription repressor HrcA C-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Schiff-base intermediate with D-ribose 5-phosphate
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Glycosyltransferase subfamily 4-like N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Penicillin-binding protein transpeptidase
Peptidoglycan recognition protein family
O-(5'-phospho-DNA)-tyrosine intermediate
Single-stranded-DNA-specific exonuclease RecJ C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
RND efflux pump membrane fusion protein barrel-sandwich
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
RNA polymerase sigma factor 70 region 4 type 2
Important for beta-aspartyl-AMP intermediate formation
Cytochrome C biogenesis protein transmembrane
Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
TRAP transporter solute receptor, TAXI family
LPXTG-motif cell wall anchor domain-containing protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
Heme-copper oxidase subunit III family profile
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Type I restriction modification DNA specificity
Activator of Hsp90 ATPase homologue 1-like C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
HicB-like antitoxin of toxin-antitoxin system
Thymidylate synthase/dCMP hydroxymethylase
Polysaccharide biosynthesis protein C-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Signal recognition particle SRP54 helical bundle
Glucose-6-phosphate isomerase prokaryote
Menaquinone biosynthesis protein MenD middle
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Gram-positive cocci surface proteins LPxTG
Transcriptional coactivator p15 (PC4) C-terminal
L-seryl-tRNA selenium transferase N-terminal
Alpha-glycerophosphate oxidase C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Cell wall-active antibiotics response LiaF-like C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Cell envelope-related transcriptional attenuator
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Cytochrome b/b6 N-terminal region profile
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Outer membrane lipoprotein-sorting protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Prepilin type IV endopeptidase peptidase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Lysidine-tRNA(Ile) synthetase C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
ATP-dependent DNA helicase RecG C-terminal
Phosphocysteine intermediate; for EIIB activity
Pseudouridine synthase I TruA alpha/beta
Tryptophan RNA-binding attenuator protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
NADH:ubiquinone oxidoreductase 30kDa subunit
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Exonuclease VII large subunit C-terminal
Glycine cleavage T-protein C-terminal barrel
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Plays an important role in substrate specificity
NIF system FeS cluster assembly NifU N-terminal
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Alpha-D-phosphohexomutase alpha/beta/alpha
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Peptide methionine sulphoxide reductase MsrA
RNA binding; important for wobble base 34 recognition
Cysteine sulfenic acid (-SOH) intermediate
Large ribosomal subunit protein uL30-like ferredoxin-like fold
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
TrbL/VirB6 plasmid conjugal transfer protein
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Involved in allosteric activation by GTP
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Restriction endonuclease type II EcoRII C-terminal
Adaptive response protein AidB N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Schiff-base intermediate with acetaldehyde
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Large ribosomal subunit protein uL6 alpha-beta
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Large ribosomal subunit protein uL15/eL18
Diacylglycerol glucosyltransferase N-terminal
Peptidase M1 membrane alanine aminopeptidase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
S-adenosyl-L-homocysteine hydrolase NAD binding
Thiamin pyrophosphokinase thiamin-binding
Interaction with polymerase core subunit RpoC
Translation elongation factor P/YeiP central
ABC-type glycine betaine transport system substrate-binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
serine-type D-Ala-D-Ala carboxypeptidase
Carboxypeptidase regulatory-like domain-containing protein
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Peptidase M17 leucyl aminopeptidase N-terminal
Glycerophosphoryl diester phosphodiesterase membrane
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Cytochrome b/b6 C-terminal region profile
Shikimate dehydrogenase substrate binding N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
6-phosphogluconate dehydrogenase C-terminal
RNA 2-O ribose methyltransferase substrate binding
DNA replication/recombination mediator RecO N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Important for interaction with partner proteins
Large ribosomal subunit protein uL2 C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
DNA-directed DNA polymerase family A palm
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Positions MEP for the nucleophilic attack