Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
YbaK/aminoacyl-tRNA synthetase-associated
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Glycosyltransferase subfamily 4-like N-terminal
RNA 2-O ribose methyltransferase substrate binding
Electron transfer via tryptophanyl radical
YVTN beta-propeller repeat-containing protein
Type I restriction modification DNA specificity
Thiol:disulfide interchange protein DsbD
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Na+/H+ antiporter MnhB subunit-related protein
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
O-(3'-phospho-DNA)-tyrosine intermediate
Outer-membrane lipoprotein carrier protein
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
SUF system FeS cluster assembly SufBD N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Glycine cleavage T-protein C-terminal barrel
O-(5'-phospho-DNA)-tyrosine intermediate
Pyruvate phosphate dikinase AMP/ATP-binding
Shikimate dehydrogenase substrate binding N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Outer membrane protein beta-barrel domain-containing protein
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
HicB-like antitoxin of toxin-antitoxin system
Urease accessory protein UreH-like transmembrane
PHA accumulation regulator DNA-binding N-terminal
Conserved hypothetical protein CHP02679 N terminus
UDP N-acetylglucosamine O-acyltransferase C-terminal
Cytochrome c7-like domain-containing protein
Aminoacyl-transfer RNA synthetases class-II family profile
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Solute-binding protein family 3/N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-96)
Important for beta-aspartyl-AMP intermediate formation
Bacterial type II secretion system protein E
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Glucan biosynthesis periplasmic MdoG C-terminal
Predicted DNA-binding protein ribbon-helix-helix
Pyruvate/ketoisovalerate oxidoreductase catalytic
ATP-dependent DNA helicase RecG C-terminal
Interaction with polymerase core subunit RpoC
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
UDP-glucose/GDP-mannose dehydrogenase C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Important for autoinhibition of adenylyltransferase activity
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Penicillin-binding protein transpeptidase
ATP synthase F1 complex delta/epsilon subunit N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Major facilitator superfamily (MFS) profile
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
RNA polymerase sigma factor 70 region 4 type 2
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Small ribosomal subunit protein uS4 N-terminal
Abortive infection protein-like C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Membrane fusion protein biotin-lipoyl like
Membrane fusion protein biotin-lipoyl like domain-containing protein
Prokaryotic-type class I peptide chain release factors
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
N6 adenine-specific DNA methyltransferase N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Thymidylate synthase/dCMP hydroxymethylase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Alpha-D-phosphohexomutase alpha/beta/alpha
Membrane insertase YidC/Oxa/ALB C-terminal
Chromosomal replication initiator protein DnaA
Pseudouridine synthase I TruA alpha/beta
Polysaccharide chain length determinant N-terminal
Alpha-glycerophosphate oxidase C-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPsynthase alpha/beta subunit N-terminal extension
Lysidine-tRNA(Ile) synthetase C-terminal
L,D-transpeptidase catalytic domain-containing protein
Putative regulatory protein FmdB Zinc ribbon
N-end rule aminoacyl transferase C-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
nitrite reductase (cytochrome; ammonia-forming)
Inner membrane protein YgaP-like transmembrane
Transposase IS116/IS110/IS902 C-terminal
Flavocytochrome c sulphide dehydrogenase flavin-binding
Arginine decarboxylase C-terminal helical
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Mannose-6-phosphate isomerase type II C-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Signal transduction histidine kinase internal region
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Ribulose bisphosphate carboxylase small subunit
Cob(I)alamin adenosyltransferase N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Cytochrome c-type biogenesis protein CcmF C-terminal
ABC-type glycine betaine transport system substrate-binding
TonB-dependent receptor-like beta-barrel
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Could play a key role in the communication between the regulatory and the substrate sites
Activator of Hsp90 ATPase homologue 1-like C-terminal
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
ABC transporter substrate-binding protein
CRISPR-associated protein Cas6 C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
NADH:ubiquinone oxidoreductase 30kDa subunit
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Peptide methionine sulfoxide reductase MsrA
Peptide methionine sulphoxide reductase MsrA
ATP-grasp fold succinyl-CoA synthetase-type
Gly-cisPro motif, important for rejection of L-amino acids
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Polymerase/histidinol phosphatase N-terminal
Important for substrate binding and specificity
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
DNA mismatch repair proteins mutS family
Antitoxin Xre/MbcA/ParS-like toxin-binding
Helix-hairpin-helix DNA-binding motif class 1
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glucose-methanol-choline oxidoreductase C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
AB hydrolase-1 domain-containing protein
NIF system FeS cluster assembly NifU C-terminal
Beta-lactamase-related domain-containing protein
L-cysteine S-thiosulfotransferase subunit SoxA
Transcription elongation factor GreA/GreB N-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Polysaccharide biosynthesis protein CapD-like
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Reversibly protonated during proton transport
Transcription factor NikR nickel binding C-terminal
Outer membrane protein assembly factor BamC
Periplasmic nitrate reductase, electron transfer subunit
TRAP C4-dicarboxylate transport system permease DctM subunit
Large ribosomal subunit protein uL15/eL18
Translation elongation factor P/YeiP central
Restriction system protein Mrr-like N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Chromosomal replication initiator DnaA C-terminal
DNA replication/recombination mediator RecO N-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
NIF system FeS cluster assembly NifU N-terminal
Type II secretion system protein GspG C-terminal
Glycoside hydrolase family 57 N-terminal
Alanyl-transfer RNA synthetases family profile
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Cytochrome oxidase subunit II copper A binding
Exonuclease VII large subunit C-terminal
RNA 3'-terminal phosphate cyclase insert
Type II secretion system protein GspC N-terminal
Fibronectin type-III domain-containing protein
Lytic transglycosylase superhelical linker
Bacterial bifunctional deaminase-reductase C-terminal
Plays an important role in substrate specificity
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Sodium/calcium exchanger membrane region
Sodium symporter small subunit predicted
Cysteine sulfenic acid (-SOH) intermediate
Interchain (with Cys-215); in linked form
Interchain (with Cys-56); in linked form
Tryptophan synthase beta chain-like PALP
Water stress and hypersensitive response
Water stress and hypersensitive response domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Glycosyl transferase family 3 N-terminal
Large ribosomal subunit protein uL2 C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
RNA binding; important for wobble base 34 recognition
HupH hydrogenase expression protein C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Disulphide bond isomerase DsbC/G N-terminal
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Survival protein SurE-like phosphatase/nucleotidase
Ribosomal RNA adenine methylase transferase N-terminal
Contractile injection system tube protein N-terminal
Cytochrome c-552/DMSO reductase-like haem-binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
S-adenosyl-L-homocysteine hydrolase NAD binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Outer membrane protein assembly factor BamE
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Zinc-regulated TonB-dependent outer membrane receptor
6-phosphogluconate dehydrogenase C-terminal
DNA-directed DNA polymerase family A palm
Choloylglycine hydrolase/NAAA C-terminal
Anthranilate synthase component I N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Required for zinc-mediated homotetramerization and catalytic activity
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Outer membrane protein assembly factor BamA
Molybdopterin cofactor biosynthesis C (MoaC)
Amidohydrolase-related domain-containing protein
Aminoacyl-tRNA synthetase class I anticodon-binding