Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Alpha-D-phosphohexomutase alpha/beta/alpha
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Peptidase M1 membrane alanine aminopeptidase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Prokaryotic-type class I peptide chain release factors
CobB/CobQ-like glutamine amidotransferase
Sporulation transcription regulator WhiA N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Polymerase/histidinol phosphatase N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Solute-binding protein family 3/N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Major facilitator superfamily (MFS) profile
Thymidylate synthase/dCMP hydroxymethylase
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Peptidoglycan recognition protein family
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
UDP-glucose/GDP-mannose dehydrogenase C-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Removed in mature form; by autocatalysis
F420-dependent glucose-6-phosphate dehydrogenase
Mandelate racemase/muconate lactonizing enzyme C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Polysaccharide chain length determinant N-terminal
RNA 2-O ribose methyltransferase substrate binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Glycoside hydrolase family 31 N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glycosyltransferase subfamily 4-like N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Tat pathway signal sequence domain protein
Tryptophan synthase beta chain-like PALP
LPXTG-motif cell wall anchor domain protein
Phosphatidic acid phosphatase type 2/haloperoxidase
Polysaccharide biosynthesis protein CapD-like
RNA polymerase sigma factor 70 region 4 type 2
DNA topoisomerase I catalytic core eukaryotic-type
Bacterial bifunctional deaminase-reductase C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Acetyl-CoA hydrolase/transferase C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Carbamoyl-phosphate synthase small subunit N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Cell envelope-related transcriptional attenuator
Plays an important role in substrate specificity
Small ribosomal subunit protein uS4 N-terminal
Reversibly protonated during proton transport
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
6-phosphogluconate dehydrogenase C-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Alpha-glycerophosphate oxidase C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Proton acceptor; for glutaminase activity
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Transcription regulator AsnC/Lrp ligand binding
Cytochrome b/b6 N-terminal region profile
Interaction with polymerase core subunit RpoC
ATP synthase F1 complex delta/epsilon subunit N-terminal
Important for substrate specificity; cannot use PPi as phosphoryl donor
Positions MEP for the nucleophilic attack
Pyridoxamine 5'-phosphate oxidase putative
Conserved hypothetical protein CHP02679 N terminus
DNA-directed DNA polymerase family A palm
Actinobacteria/chloroflexi VLRF1 release factor
Pyruvate phosphate dikinase AMP/ATP-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Penicillin-binding protein transpeptidase
Inosine/uridine-preferring nucleoside hydrolase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Cation-transporting P-type ATPase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Subtilisin-like protease fibronectin type-III
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Cysteine sulfenic acid (-SOH) intermediate
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Transposase IS116/IS110/IS902 C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
Putative oxidoreductase/dehydrogenase Rossmann-like
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein uL15/eL18
Heat-inducible transcription repressor HrcA C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Glycine cleavage T-protein C-terminal barrel
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Translation elongation factor P/YeiP central
Cytochrome C biogenesis protein transmembrane
O-(5'-phospho-DNA)-tyrosine intermediate
Periplasmic binding protein domain-containing protein
RsbT co-antagonist protein RsbRD N-terminal
DNA replication/recombination mediator RecO N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Shikimate dehydrogenase substrate binding N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Glycosyl transferase family 3 N-terminal
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
PhoD-like phosphatase metallophosphatase
Nitrite/Sulfite reductase ferredoxin-like
Bacterial type II secretion system protein E
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
YbaK/aminoacyl-tRNA synthetase-associated
Cell wall-active antibiotics response LiaF-like C-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
SsuA/THI5-like domain-containing protein
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Putative Flp pilus-assembly TadG-like N-terminal
Polysaccharide biosynthesis protein C-terminal
Release factor glutamine methyltransferase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Phosphatidate phosphatase APP1 catalytic
NADH:ubiquinone oxidoreductase-like 20kDa subunit
EfeO-type cupredoxin-like domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
ABC-type glycine betaine transport system substrate-binding
Large ribosomal subunit protein uL6 alpha-beta
Pyruvate dehydrogenase E1 component middle
Peptidase MA-like domain-containing protein
Alanyl-transfer RNA synthetases family profile
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Peptidase M43 pregnancy-associated plasma-A
Peptidase M43 pregnancy-associated plasma-A domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Large ribosomal subunit protein uL2 C-terminal
2-oxoacid dehydrogenase acyltransferase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Peptidase S9 prolyl oligopeptidase catalytic
Protein O-mannosyl-transferase C-terminal four TM
Essential for prephenate dehydratase activity
Schiff-base intermediate with D-ribose 5-phosphate
Increases nucleophilicity of active site Cys
Pseudouridine synthase I TruA alpha/beta
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Cytochrome b561 bacterial/Ni-hydrogenase
Phosphotransferase system enzyme I N-terminal
Chromosomal replication initiator DnaA C-terminal
Adaptive response protein AidB N-terminal
Trigger factor ribosome-binding bacterial
SUF system FeS cluster assembly SufBD N-terminal
ABC transporter substrate-binding protein PnrA-like
Dinitrogenase iron-molybdenum cofactor biosynthesis
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Prepilin type IV endopeptidase peptidase
Homogentisate 1,2-dioxygenase C-terminal
NIF system FeS cluster assembly NifU N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Saccharopine dehydrogenase-like C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle