Penicillin-binding protein transpeptidase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Gly-cisPro motif, important for rejection of L-amino acids
Glycosyltransferase subfamily 4-like N-terminal
6-phosphogluconate dehydrogenase C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Cytochrome b/b6 N-terminal region profile
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Pyruvate phosphate dikinase AMP/ATP-binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Outer membrane protein beta-barrel domain-containing protein
Solute-binding protein family 3/N-terminal
Microcin J25-processing protein McjB C-terminal
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Thiamin pyrophosphokinase thiamin-binding
Alanyl-transfer RNA synthetases family profile
General stress protein FMN-binding split barrel
Phosphocysteine intermediate; for EIIB activity
Cell envelope-related transcriptional attenuator
Glycosyl hydrolase family 30 beta sandwich
Major facilitator superfamily (MFS) profile
DNA replication/recombination mediator RecO N-terminal
Release factor glutamine methyltransferase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Trigger factor ribosome-binding bacterial
Alpha-glycerophosphate oxidase C-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Transcriptional regulator LacI/GalR-like sensor
Aminoacyl-transfer RNA synthetases class-II family profile
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Glycosyl hydrolase-like 10 domain-containing protein
Schiff-base intermediate with acetaldehyde
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Prokaryotic-type class I peptide chain release factors
Resolvase/invertase-type recombinase catalytic
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Bacterial Ig-like domain-containing protein
Small ribosomal subunit protein uS4 N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Could play a key role in the communication between the regulatory and the substrate sites
Survival protein SurE-like phosphatase/nucleotidase
Large ribosomal subunit protein uL2 C-terminal
PrcB C-terminal domain-containing protein
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Molybdopterin cofactor biosynthesis C (MoaC)
PsbP C-terminal domain-containing protein
Gp5/Type VI secretion system Vgr protein OB-fold
Bacterial type II secretion system protein E
Contractile injection system tube protein N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Right handed beta helix domain-containing protein
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Copper amine oxidase-like domain-containing protein
S-adenosylmethionine-dependent methyltransferase
Phosphatidate phosphatase APP1 catalytic
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Positions MEP for the nucleophilic attack
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Exonuclease VII large subunit C-terminal
Glycosyl hydrolases family 2 sugar binding
Outer membrane insertion C-terminal signal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Organic solvent tolerance-like N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Tryptophan synthase beta chain-like PALP
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Peptidase C39-like domain-containing protein
Polymerase/histidinol phosphatase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Glycogen debranching enzyme bacterial and archaeal type N-terminal
RNA polymerase sigma factor 70 region 4 type 2
SUF system FeS cluster assembly SufBD N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Regulator of chromosome condensation RCC1
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Essential for prephenate dehydratase activity
4'-phosphopantetheinyl transferase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
RNA methyltransferase SpoU/TrmH type C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Ionotropic glutamate receptor C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Pyridine nucleotide-disulphide oxidoreductase dimerisation
RNA 2-O ribose methyltransferase substrate binding
Superoxide dismutase copper/zinc binding protein
Translation elongation factor P/YeiP central
Carbohydrate binding module xylan-binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Phosphatidic acid phosphatase type 2/haloperoxidase
DR2241 4Fe-4S iron-sulfur cluster binding
Schiff-base intermediate with D-ribose 5-phosphate
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Arginine decarboxylase C-terminal helical
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Ribosome maturation factor RimP N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Type II secretion system protein GspE N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Involved in allosteric activation by GTP
Pyruvate dehydrogenase E1 component middle
Glycosyl transferase family 3 N-terminal
C-type lysozyme inhibitor domain-containing protein
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Alpha-D-phosphohexomutase alpha/beta/alpha
Saccharopine dehydrogenase-like C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Membrane insertase YidC/Oxa/ALB C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Polysaccharide chain length determinant N-terminal
Anthranilate synthase component I N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
ABC transporter substrate-binding protein PnrA-like
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Important for interaction with partner proteins
Interacts with tRNA; defines subfamily-specific binding signature
Probable endolytic peptidoglycan transglycosylase RlpA
Membrane fusion protein biotin-lipoyl like
Polysaccharide biosynthesis protein CapD-like
Outer membrane lipoprotein carrier protein LolA
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Glutathionylspermidine synthase pre-ATP-grasp-like
Water stress and hypersensitive response
Carbamoyl-phosphate synthase small subunit N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Inosine/uridine-preferring nucleoside hydrolase
tRNA pseudouridylate synthase B C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
DNA topoisomerase I catalytic core eukaryotic-type
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
DNA primase/polymerase bifunctional N-terminal
Siroheme decarboxylase AsnC-like ligand binding
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
RNA binding; important for wobble base 34 recognition
Phosphomannose isomerase type I catalytic
Cytochrome C biogenesis protein transmembrane
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Large ribosomal subunit protein uL15/eL18
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase C-terminal
Superoxide dismutase copper/zinc binding
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO
Inward rectifier potassium channel C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Peptidase M1 membrane alanine aminopeptidase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Phosphoribosylformylglycinamidine synthase linker
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Cell wall-active antibiotics response LiaF-like C-terminal
Cell wall-active antibiotics response LiaF-like C-terminal domain-containing protein
Ribose-phosphate pyrophosphokinase N-terminal
ABC-type glycine betaine transport system substrate-binding
Periplasmic copper-binding protein NosD beta helix
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Transcription regulator AsnC/Lrp ligand binding
Pseudouridine synthase I TruA alpha/beta
Ribosomal RNA adenine methylase transferase N-terminal
DNA mismatch repair proteins mutS family
RND efflux pump membrane fusion protein barrel-sandwich
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glycoside hydrolase family 31 N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Phosphodiester glycosidase domain-containing protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Nicotinamide phosphoribosyltransferase N-terminal
Gamma-glutamylcyclotransferase AIG2-like
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Peptide methionine sulphoxide reductase MsrA
2-(S-cysteinyl)pyruvic acid O-phosphothioketal