TonB-dependent receptor-like beta-barrel
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
RNA polymerase sigma factor 70 region 4 type 2
Peptidase M1 membrane alanine aminopeptidase
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Quercetin 2,3-dioxygenase C-terminal cupin
ATP-dependent DNA helicase RecG C-terminal
Restriction system protein Mrr-like N-terminal
Major facilitator superfamily (MFS) profile
Tryptophan synthase beta chain-like PALP
Penicillin-binding protein transpeptidase
Peptide methionine sulfoxide reductase MsrB
Heme-copper oxidase subunit III family profile
Type IX secretion system protein PorV domain-containing protein
Bacterial repeat domain-containing protein
Polysaccharide biosynthesis protein CapD-like
Polymerase/histidinol phosphatase N-terminal
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Aminoacyl-transfer RNA synthetases class-II family profile
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Inner membrane protein YgaP-like transmembrane
3-keto-disaccharide hydrolase domain-containing protein
NADH:ubiquinone oxidoreductase 30kDa subunit
O-(5'-phospho-DNA)-tyrosine intermediate
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Organic solvent tolerance-like N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Beta-hexosaminidase bacterial type N-terminal domain-containing protein
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Glycoside hydrolase family 31 N-terminal
Peptidase M10A and M12B matrixin and adamalysin
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Cytochrome b561 bacterial/Ni-hydrogenase
Thymidylate synthase/dCMP hydroxymethylase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Alpha-D-phosphohexomutase alpha/beta/alpha
RND efflux pump membrane fusion protein barrel-sandwich
Outer membrane protein beta-barrel domain-containing protein
Bacterial bifunctional deaminase-reductase C-terminal
Surface glycan-binding protein B xyloglucan binding
Polysaccharide biosynthesis protein C-terminal
General stress protein FMN-binding split barrel
Peptidase S9 prolyl oligopeptidase catalytic
Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein
Gamma-glutamylcyclotransferase AIG2-like
3-hydroxyacyl-CoA dehydrogenase C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Signal transduction histidine kinase internal region
Beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Transposase IS116/IS110/IS902 C-terminal
Regulator of chromosome condensation RCC1
Large ribosomal subunit protein uL6 alpha-beta
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Endoribonuclease L-PSP/chorismate mutase-like
Cellulose-binding Sde182 nucleoside hydrolase-like
Cellulose-binding Sde182 nucleoside hydrolase-like domain-containing protein
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolase family 30 beta sandwich
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Glycosyl hydrolases family 2 sugar binding
Gliding motility-associated C-terminal domain-containing protein
Activator of Hsp90 ATPase homologue 1-like C-terminal
Lipocalin-like domain-containing protein
Formamidopyrimidine-DNA glycosylase catalytic
TonB C-terminal domain-containing protein
Glycoside hydrolase family 42 N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
SMODS-associated and fused to various effectors
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Cation-transporting P-type ATPase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-101)
Chromosomal replication initiator DnaA C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Large ribosomal subunit protein uL15/eL18
Twin-arginine translocation pathway signal
Glycosyltransferase subfamily 4-like N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Outer membrane lipoprotein-sorting protein
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Collagen triple helix repeat-containing protein
Glycosyl-hydrolase 97 C-terminal oligomerisation
Phosphatidic acid phosphatase type 2/haloperoxidase
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Gly-cisPro motif, important for rejection of L-amino acids
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Resolvase/invertase-type recombinase catalytic
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
LPS export ABC transporter periplasmic protein LptC
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Positions MEP for the nucleophilic attack
SUF system FeS cluster assembly SufBD N-terminal
Proton acceptor; for glutaminase activity
Schiff-base intermediate with substrate; via pyruvic acid
Pyruvate phosphate dikinase AMP/ATP-binding
Beta-lactamase class A catalytic domain-containing protein
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Glycosyl hydrolase-like 10 domain-containing protein
Right handed beta helix domain-containing protein
Transglutaminase domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Alpha-N-acetylglucosaminidase C-terminal
Alpha-N-acetylglucosaminidase N-terminal
Alpha-N-acetylglucosaminidase tim-barrel
Reversibly protonated during proton transport
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Secretion system C-terminal sorting domain-containing protein
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Gp5/Type VI secretion system Vgr protein OB-fold
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Gliding motility-associated protein GldM N-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Ribosomal RNA adenine methylase transferase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Tetratricopeptide TPR_1 repeat-containing protein
Release factor glutamine methyltransferase N-terminal
Carboxypeptidase regulatory-like domain-containing protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Alpha galactosidase C-terminal beta sandwich
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Putative glycogen debranching enzyme N-terminal
Membrane fusion protein biotin-lipoyl like
Shows 20% increase in activity and enhanced regiospecificity against the para-form of the product.
Shows 50% increase in activity and enhanced regiospecificity against the para-form of the product.
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
Histidine-specific methyltransferase SAM-dependent
SusE outer membrane protein domain-containing protein
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Alginate lyase domain-containing protein
Four-carbon acid sugar kinase N-terminal
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Pyridoxamine 5'-phosphate oxidase putative
Translation elongation factor P/YeiP central
Survival protein SurE-like phosphatase/nucleotidase
DNA mismatch repair proteins mutS family
Small ribosomal subunit protein uS4 N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Secretin/TonB short N-terminal domain-containing protein
RNA 2-O ribose methyltransferase substrate binding
Integral membrane protein YccS N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glycoside hydrolase GH146 substrate-binding
Glycoside hydrolase GH146 substrate-binding domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
6-phosphogluconate dehydrogenase C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Carbamoyl-phosphate synthase small subunit N-terminal
Probable endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Peptide methionine sulphoxide reductase MsrA
Prokaryotic-type class I peptide chain release factors
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Antitoxin Xre/MbcA/ParS-like toxin-binding
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Carboxypeptidase-like regulatory domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
Asl1-like glycosyl hydrolase catalytic domain-containing protein
Lysidine-tRNA(Ile) synthetase C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
RNA binding; important for wobble base 34 recognition
Thiamine pyrophosphate enzyme TPP-binding
AB hydrolase-1 domain-containing protein
ATP-grasp fold succinyl-CoA synthetase-type
Cation-transporting P-type ATPase C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glycoside hydrolase family 38 N-terminal
AraC-type arabinose-binding/dimerisation
Aminoacyl-tRNA synthetase class I anticodon-binding
Outer membrane lipoprotein carrier protein LolA
Beta-hexosaminidase bacterial type N-terminal
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Metallo-beta-lactamase domain-containing protein
Phosphoribosylformylglycinamidine synthase linker
Periplasmic copper-binding protein NosD beta helix
Pyrroline-5-carboxylate reductase catalytic N-terminal
Large ribosomal subunit protein uL2 C-terminal
SusD-like N-terminal domain-containing protein
SMODS-associating 2TM beta-strand rich effector
WD40-like beta Propeller containing protein
Gliding motility-associated protein GldM C-terminal domain-containing protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Shikimate dehydrogenase substrate binding N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Cytochrome C biogenesis protein transmembrane
Pectinesterase inhibitor domain-containing protein
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
S-adenosylmethionine-dependent methyltransferase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
peptide-methionine (R)-S-oxide reductase
Putative beta-lactamase-inhibitor-like PepSY-like
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
CD-NTase associated protein 4-like DNA endonuclease
Acetylserotonin O-methyltransferase dimerisation
Urease accessory protein UreH-like transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Anthranilate synthase component I N-terminal
Alpha-glycerophosphate oxidase C-terminal
Polysaccharide chain length determinant N-terminal
Trigger factor ribosome-binding bacterial
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Glycosyl transferase family 3 N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
GxGYxYP putative glycoside hydrolase C-terminal
GxGYxYP putative glycoside hydrolase N-terminal
Gylcosyl hydrolase 115 C-terminal domain-containing protein
Homogentisate 1,2-dioxygenase N-terminal
Glycoside hydrolase family 5 domain-containing protein
Sporulation stage II protein D amidase enhancer LytB N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
DNA-directed DNA polymerase family A palm
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Acyltransferase MbtK/IucB-like conserved
DNA replication/recombination mediator RecO N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
S-adenosyl-L-homocysteine hydrolase NAD binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Four-carbon acid sugar kinase nucleotide binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Leucine-binding protein domain-containing protein
Alginate export domain-containing protein
Gliding motility-associated protein GldM C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
ABC-type uncharacterised transport system
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
3-beta hydroxysteroid dehydrogenase/isomerase
Glycine cleavage T-protein C-terminal barrel
Saccharopine dehydrogenase-like C-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Inward rectifier potassium channel C-terminal
Fibrobacter succinogenes major paralogous
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Sialate O-acetylesterase domain-containing protein
NAD(P) transhydrogenase alpha subunit C-terminal
tRNA pseudouridylate synthase B C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Phosphomannose isomerase type I catalytic
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
T9SS type A sorting domain-containing protein
Pseudouridine synthase I TruA alpha/beta
Schiff-base intermediate with acetaldehyde
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding