Major facilitator superfamily (MFS) profile
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Exonuclease VII large subunit C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
FAD-dependent oxidoreductase 2 FAD binding
Methionyl-tRNA synthetase anticodon-binding
Phosphocysteine intermediate; for EIIB activity
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Aminoacyl-transfer RNA synthetases class-II family profile
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Schiff-base intermediate with substrate; via pyruvic acid
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
RNA 2-O ribose methyltransferase substrate binding
LPXTG-motif cell wall anchor domain protein
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Large ribosomal subunit protein uL6 alpha-beta
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Thiamin pyrophosphokinase thiamin-binding
Tryptophan synthase beta chain-like PALP
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Bacterial type II secretion system protein E
Schiff-base intermediate with acetaldehyde
Trigger factor ribosome-binding bacterial
Mannose-6-phosphate isomerase type II C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Mandelate racemase/muconate lactonizing enzyme C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
tRNA pseudouridylate synthase B C-terminal
Translation elongation factor P/YeiP central
6-phosphogluconate dehydrogenase C-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Cation-transporting P-type ATPase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Large ribosomal subunit protein uL15/eL18
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Ribosomal RNA adenine methylase transferase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Polymerase/histidinol phosphatase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Phosphotransferase system enzyme I N-terminal
Glycoside hydrolase family 31 N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Alanyl-transfer RNA synthetases family profile
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Chromosomal replication initiator DnaA C-terminal
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Could play a key role in the communication between the regulatory and the substrate sites
Beta-xylosidase C-terminal Concanavalin A-like
Important for beta-aspartyl-AMP intermediate formation
Phosphotransferase system EIIB component type 2/3
Inosine/uridine-preferring nucleoside hydrolase
RNA binding; important for wobble base 34 recognition
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Diacylglycerol glucosyltransferase N-terminal
Prokaryotic-type class I peptide chain release factors
Glycosyl hydrolases family 2 sugar binding
Helix-hairpin-helix DNA-binding motif class 1
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Penicillin-binding protein transpeptidase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Interaction with polymerase core subunit RpoC
Ribose-phosphate pyrophosphokinase N-terminal
O-(phosphoribosyl dephospho-coenzyme A)serine
Pyruvate phosphate dikinase AMP/ATP-binding
O-(3'-phospho-DNA)-tyrosine intermediate
O-(5'-phospho-DNA)-tyrosine intermediate
Proton acceptor; for glutaminase activity
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
NIF system FeS cluster assembly NifU C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
DNA replication/recombination mediator RecO N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Important for interaction with partner proteins
Signal recognition particle SRP54 helical bundle
Sporulation transcription regulator WhiA N-terminal
Small ribosomal subunit protein uS4 N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Phosphomannose isomerase type I catalytic
Polysaccharide chain length determinant N-terminal
Peptidase C39-like domain-containing protein
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Transcriptional regulator TetR C-terminal Firmicutes type
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Choloylglycine hydrolase/NAAA C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Gram-positive pilin backbone subunit 2 Cna-B-like
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
NIF system FeS cluster assembly NifU N-terminal
Threonine/serine exporter-like N-terminal
ABC transporter substrate-binding protein PnrA-like
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal