D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Aconitase A/isopropylmalate dehydratase small subunit swivel
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Plays an important role in substrate specificity
Schiff-base intermediate with D-ribose 5-phosphate
Membrane fusion protein biotin-lipoyl like
RND efflux pump membrane fusion protein barrel-sandwich
Glucosamine/galactosamine-6-phosphate isomerase
Cysteine sulfenic acid (-SOH) intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Interchain (with Cys-217); in linked form
Interchain (with Cys-56); in linked form
Transposase IS116/IS110/IS902 C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Inner membrane protein YgaP-like transmembrane
Alpha-D-phosphohexomutase alpha/beta/alpha
Type III secretion system flagellar brake protein YcgR PilZN
Positions MEP for the nucleophilic attack
Alanyl-transfer RNA synthetases family profile
HicB-like antitoxin of toxin-antitoxin system
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Aminoacyl-transfer RNA synthetases class-II family profile
ABC-type uncharacterised transport system
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Major facilitator superfamily (MFS) profile
Dinitrogenase iron-molybdenum cofactor biosynthesis
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
D-galactarate/Altronate dehydratase C-terminal
Prepilin type IV endopeptidase peptidase
CD-NTase associated protein 4-like DNA endonuclease
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Pyruvate phosphate dikinase AMP/ATP-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Survival protein SurE-like phosphatase/nucleotidase
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Type 4 fimbrial biogenesis protein PilX N-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Phosphatidic acid phosphatase type 2/haloperoxidase
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Cation-transporting P-type ATPase N-terminal
Large ribosomal subunit protein uL2 C-terminal
Glutamate synthase alpha subunit C-terminal
2,4-diaminopentanoate dehydrogenase C-terminal
Dihydrodipicolinate reductase N-terminal
Phosphocysteine intermediate; for EIIB activity
Reversibly protonated during proton transport
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Bacterial type II secretion system protein E
Sporulation transcription regulator WhiA N-terminal
Polymerase/histidinol phosphatase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
DNA replication/recombination mediator RecO N-terminal
Flagellar Assembly Protein A N-terminal region
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Release factor glutamine methyltransferase N-terminal
6-phosphogluconate dehydrogenase C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
NIF system FeS cluster assembly NifU N-terminal
Penicillin-binding protein transpeptidase
Glycosyltransferase subfamily 4-like N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Cell envelope-related transcriptional attenuator
Translation elongation factor P/YeiP central
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Transcriptional regulator LacI/GalR-like sensor
Glycoside hydrolase family 31 N-terminal
Cytochrome C biogenesis protein transmembrane
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Lysidine-tRNA(Ile) synthetase C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Peptidase S9 prolyl oligopeptidase catalytic
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Polysaccharide biosynthesis protein C-terminal
Resolvase/invertase-type recombinase catalytic
Peptidase M1 membrane alanine aminopeptidase
ABC-type glycine betaine transport system substrate-binding
Important for beta-aspartyl-AMP intermediate formation
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Chromosomal replication initiator DnaA C-terminal
Interaction with polymerase core subunit RpoC
Tryptophan synthase beta chain-like PALP
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Helix-hairpin-helix DNA-binding motif class 1
Important for interaction with partner proteins
Aspartate/homoserine dehydrogenase NAD-binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
ATP synthase F1 complex delta/epsilon subunit N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Membrane insertase YidC/Oxa/ALB C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; for glutaminase activity
Small ribosomal subunit protein uS4 N-terminal
Cyclic nucleotide-binding domain-containing protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Molybdopterin cofactor biosynthesis C (MoaC)
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Phosphodiester glycosidase domain-containing protein
Homologous-pairing protein 2 winged helix
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Schiff-base intermediate with acetaldehyde
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Phosphomannose isomerase type I catalytic
Exonuclease VII large subunit C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Glycosyl transferase family 3 N-terminal
Sporulation stage IV protein A C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
6-phosphogluconate dehydrogenase NADP-binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Flagellar motor switch protein FliN-like C-terminal
Pyrimidine nucleoside phosphorylase C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Mannose-6-phosphate isomerase type II C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
RNA 2-O ribose methyltransferase substrate binding
Glycine cleavage T-protein C-terminal barrel
ABC transporter substrate-binding protein PnrA-like
Putative oxidoreductase/dehydrogenase Rossmann-like
Ribosomal RNA adenine methylase transferase N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Probable transposase IS891/IS1136/IS1341
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Large ribosomal subunit protein uL6 alpha-beta
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Phosphotransferase system enzyme I N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Flagellar hook-length control protein-like C-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
DNA polymerase III delta subunit C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
RNA binding; important for wobble base 34 recognition
SUF system FeS cluster assembly SufBD N-terminal
NIF system FeS cluster assembly NifU C-terminal
Polysaccharide chain length determinant N-terminal
Magnesium transporter MgtE intracellular
Heat-inducible transcription repressor HrcA C-terminal
NADH-rubredoxin oxidoreductase C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
N(4)-bis(aminopropyl)spermidine synthase C-terminal
Glucose-6-phosphate isomerase prokaryote
DNA mismatch repair proteins mutS family
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Thiamin pyrophosphokinase thiamin-binding
serine-type D-Ala-D-Ala carboxypeptidase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Dihydrodipicolinate reductase C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Phosphoribosylformylglycinamidine synthase linker
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Type I phosphodiesterase/nucleotide pyrophosphatase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Transcription factor NikR nickel binding C-terminal
Na+-translocating membrane potential-generating system MpsC
Large ribosomal subunit protein uL15/eL18
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Pseudouridine synthase I TruA alpha/beta
Type IV methyl-directed restriction enzyme EcoKMcrB subunit DNA-binding