Major facilitator superfamily (MFS) profile
Involved in ionization of N3 of dUMP, leading to its activation
NADH-rubredoxin oxidoreductase C-terminal
Polysaccharide biosynthesis protein CapD-like
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Glycoside hydrolase family 31 N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Aminoacyl-transfer RNA synthetases class-II family profile
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Anthranilate synthase component I N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Glycosyltransferase subfamily 4-like N-terminal
NIF system FeS cluster assembly NifU C-terminal
D-galactarate/Altronate dehydratase C-terminal
Cell envelope-related transcriptional attenuator
Gfo/Idh/MocA-like oxidoreductase C-terminal
Reversibly protonated during proton transport
Extracellular solute-binding protein family 1
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Release factor glutamine methyltransferase N-terminal
Type III restriction enzyme C-terminal endonuclease
Inosine/uridine-preferring nucleoside hydrolase
Penicillin-binding protein transpeptidase
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Sporulation stage II protein D amidase enhancer LytB N-terminal
Membrane fusion protein biotin-lipoyl like
RND efflux pump membrane fusion protein barrel-sandwich
TrbL/VirB6 plasmid conjugal transfer protein
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
DNA-directed DNA polymerase family A palm
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
DNA replication/recombination mediator RecO N-terminal
Flagellar motor switch protein FliN-like C-terminal
Glycoside hydrolase family 42 N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Carbamoyl-phosphate synthase small subunit N-terminal
Tryptophan synthase beta chain-like PALP
Alpha-D-phosphohexomutase alpha/beta/alpha
DNA mismatch repair proteins mutS family
Phosphatidylglycerol lysyltransferase C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Small ribosomal subunit protein uS4 N-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Type I restriction modification DNA specificity
Helix-turn-helix conjugative transposon-like
Peptidase M1 membrane alanine aminopeptidase
Flagellar hook-length control protein-like C-terminal
Magnesium transporter MgtE intracellular
Could be important to modulate the pK values of the two catalytic cysteine residues
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
N-sulphoglucosamine sulphohydrolase C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Heat-inducible transcription repressor HrcA C-terminal
tRNA pseudouridylate synthase B C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Resolvase/invertase-type recombinase catalytic
Proton acceptor; for glutaminase activity
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Probable transposase IS891/IS1136/IS1341
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Polysaccharide biosynthesis protein C-terminal
Important for beta-aspartyl-AMP intermediate formation
Putative regulatory protein FmdB Zinc ribbon
Polymerase/histidinol phosphatase N-terminal
Solute-binding protein family 3/N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Large ribosomal subunit protein bL9 C-terminal
Involved in allosteric activation by GTP
Mannose-6-phosphate isomerase type II C-terminal
CobB/CobQ-like glutamine amidotransferase
Cytochrome C biogenesis protein transmembrane
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
RNA binding; important for wobble base 34 recognition
Tryptophan RNA-binding attenuator protein
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Glucosamine/galactosamine-6-phosphate isomerase
Alpha galactosidase C-terminal beta sandwich
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Bacterial type II secretion system protein E
O-(5'-phospho-DNA)-tyrosine intermediate
ABC-type glycine betaine transport system substrate-binding
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
SUF system FeS cluster assembly SufBD N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
NADH:flavin oxidoreductase/NADH oxidase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Prepilin type IV endopeptidase peptidase
6-phosphogluconate dehydrogenase NADP-binding
DNA primase/polymerase bifunctional N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Large ribosomal subunit protein uL6 alpha-beta
Type IV secretion system coupling protein TraD DNA-binding
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
ATP synthase F1 complex delta/epsilon subunit N-terminal
Important for interaction with partner proteins
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Prokaryotic-type class I peptide chain release factors
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Large ribosomal subunit protein uL2 C-terminal
Glycosyl-hydrolase 97 C-terminal oligomerisation
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
NIF system FeS cluster assembly NifU N-terminal
CRISPR-associated protein Cas6 C-terminal
Methylene-tetrahydrofolate reductase C-terminal
Phosphoribosylformylglycinamidine synthase linker
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Exonuclease VII large subunit C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Thiamin pyrophosphokinase thiamin-binding
Large ribosomal subunit protein uL15/eL18
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Glycosyl transferase family 3 N-terminal
PrcB C-terminal domain-containing protein
Pyruvate phosphate dikinase AMP/ATP-binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
NfeD-like C-terminal domain-containing protein
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Glutamate synthase alpha subunit C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Interchain (with Cys-216); in linked form
Interchain (with Cys-50); in linked form
NADH-ubiquinone oxidoreductase 51kDa subunit FMN-binding
Nucleic acid binding OB-fold tRNA/helicase-type
Terminase large subunit-like endonuclease
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Dipicolinate synthase subunit A N-terminal
Ferrous iron transport protein B C-terminal
RNA 2-O ribose methyltransferase substrate binding
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Replicative helicase inhibitor G39P N-terminal
Gamma-glutamylcyclotransferase AIG2-like
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Pseudouridine synthase I TruA alpha/beta
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Transcription regulator AsnC/Lrp ligand binding
Transcription elongation factor GreA/GreB C-terminal
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Chromosomal replication initiator DnaA C-terminal
Interaction with polymerase core subunit RpoC
Transcription elongation factor GreA/GreB N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glycosyl-hydrolase family 116 N-terminal
Glycosyl-hydrolase family 116 catalytic region
Survival protein SurE-like phosphatase/nucleotidase
Sporulation stage IV protein A C-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Cation-transporting P-type ATPase N-terminal
Bacteriophage lambda Replication protein O N-terminal
6-hydroxymethylpterin diphosphokinase MptE-like
Translation elongation factor P/YeiP central
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Transcription factor NikR nickel binding C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Damage-control phosphatase ARMT1-like metal-binding
Alanyl-transfer RNA synthetases family profile
Membrane insertase YidC/Oxa/ALB C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
ABC-type uncharacterised transport system