Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Pseudouridine synthase I TruA alpha/beta
TonB-dependent receptor-like beta-barrel
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Glycosyltransferase subfamily 4-like N-terminal
General stress protein FMN-binding split barrel
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Organic solvent tolerance-like N-terminal
Prepilin type IV endopeptidase peptidase
Large ribosomal subunit protein uL6 alpha-beta
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
S-adenosylmethionine-dependent methyltransferase
RND efflux pump membrane fusion protein barrel-sandwich
Glucose-methanol-choline oxidoreductase N-terminal
Outer membrane protein assembly factor BamA
Outer membrane protein beta-barrel domain-containing protein
Thiolase-like protein type 1 additional C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Polysaccharide chain length determinant N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Major facilitator superfamily (MFS) profile
Essential for prephenate dehydratase activity
Bacterial type II secretion system protein E
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Quercetin 2,3-dioxygenase C-terminal cupin
Important for interaction with partner proteins
Tetrahydrodipicolinate-N-succinyltransferase chain A
Phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease 2
Flagellar motor switch protein FliN-like C-terminal
Tryptophan synthase beta chain-like PALP
Peptide methionine sulfoxide reductase MsrA
Peptide methionine sulphoxide reductase MsrA
Beta-lactamase-related domain-containing protein
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Outer membrane protein assembly factor BamD
Inosine/uridine-preferring nucleoside hydrolase
Right handed beta helix domain-containing protein
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Large ribosomal subunit protein uL15/eL18
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Release factor glutamine methyltransferase N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Chromosomal replication initiator DnaA C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Major facilitator superfamily associated
Glucosamine/galactosamine-6-phosphate isomerase
Cytochrome c oxidase subunit IV bacterial aa3 type
Aminoacyl-tRNA synthetase class I anticodon-binding
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Phosphatidic acid phosphatase type 2/haloperoxidase
PhoD-like phosphatase metallophosphatase
Alanyl-transfer RNA synthetases family profile
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Penicillin-binding protein transpeptidase
Interaction with polymerase core subunit RpoC
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
TonB C-terminal domain-containing protein
PHA accumulation regulator DNA-binding N-terminal
Exonuclease VII large subunit C-terminal
Polysaccharide biosynthesis protein C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Saccharopine dehydrogenase-like C-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
YbaK/aminoacyl-tRNA synthetase-associated
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
O-(5'-phospho-DNA)-tyrosine intermediate
Glycosyl-hydrolase 97 C-terminal oligomerisation
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Translation elongation factor P/YeiP central
Polysaccharide biosynthesis protein CapD-like
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
Gfo/Idh/MocA-like oxidoreductase N-terminal
Plays an important role in substrate specificity
Phosphocysteine intermediate; for EIIB activity
Anthranilate synthase component I N-terminal
Glycosyl transferase family 3 N-terminal
Reversibly protonated during proton transport
Ribose-phosphate pyrophosphokinase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Auto-transporter adhesin head GIN domain-containing protein
Peptidase M1 membrane alanine aminopeptidase
UDP N-acetylglucosamine O-acyltransferase C-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Glutathionylspermidine synthase pre-ATP-grasp-like
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Sialate O-acetylesterase domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
Beta-lactamase hydrolase-like protein phosphatase-like
Carbamoyl-phosphate synthase small subunit N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Prokaryotic-type class I peptide chain release factors
Pyridoxamine 5'-phosphate oxidase putative
Flagella basal body P-ring formation protein FlgA
Alpha/beta hydrolase fold-3 domain-containing protein
DNA-directed DNA polymerase family A palm
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Resolvase/invertase-type recombinase catalytic
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
RNA binding; important for wobble base 34 recognition
Alpha-D-phosphohexomutase alpha/beta/alpha
Thymidylate synthase/dCMP hydroxymethylase
Translocation and assembly module subunit TamA
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Glycoside hydrolase family 42 N-terminal
Pilus formation protein N-terminal domain-containing protein
tRNA pseudouridylate synthase B C-terminal
Glucose/Sorbosone dehydrogenase domain-containing protein
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Polymerase/histidinol phosphatase N-terminal
Inner membrane protein YgaP-like transmembrane
ABC-type transport auxiliary lipoprotein component
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Endolytic peptidoglycan transglycosylase RlpA
NAD(+) hydrolase ThsA Sir2/TIR-associating SLOG
Phosphoribosylformylglycinamidine synthase linker
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
RNA 2-O ribose methyltransferase substrate binding
Sugar fermentation stimulation protein C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Schiff-base intermediate with substrate; via pyruvic acid
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Beta-barrel assembly machine subunit BamF
Required for zinc-mediated homotetramerization and catalytic activity
DNA replication/recombination mediator RecO N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Beta/gamma crystallin 'Greek key' domain-containing protein
Membrane insertase YidC/Oxa/ALB C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Large ribosomal subunit protein uL30-like ferredoxin-like fold
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
CagE TrbE VirB component of type IV transporter system central
Heme-copper oxidase subunit III family profile
Could be important to modulate the pK values of the two catalytic cysteine residues
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Pyruvate phosphate dikinase AMP/ATP-binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Activator of Hsp90 ATPase homologue 1-like C-terminal
Required for dimer formation and molybdate binding
Cobaltochelatase subunit CobS N-terminal
N-end rule aminoacyl transferase C-terminal
Interacts with tRNA; defines subfamily-specific binding signature
NAD(P) transhydrogenase alpha subunit C-terminal
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Beta-hexosaminidase bacterial type N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Signal transduction histidine kinase internal region
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Histidine phosphotransferase ChpT C-terminal
DNA mismatch repair proteins mutS family
Phosphatidylglycerol lysyltransferase C-terminal
DNA primase/polymerase bifunctional N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Small ribosomal subunit protein uS4 N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Peptidase M20 dimerisation domain-containing protein
Biopterin-dependent aromatic amino acid hydroxylase family profile
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Survival protein SurE-like phosphatase/nucleotidase
Cytochrome c-type biogenesis protein CcmF C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Large ribosomal subunit protein uL2 C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glycine zipper domain-containing protein
Methionyl-tRNA synthetase anticodon-binding
Lysozyme inhibitor LprI N-terminal domain-containing protein
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Glycine cleavage T-protein C-terminal barrel
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Proton acceptor; for glutaminase activity
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Mannose-6-phosphate isomerase type II C-terminal