Heme-copper oxidase subunit III family profile
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Polypeptide-transport-associated ShlB-type
Proton acceptor; for glutaminase activity
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Major facilitator superfamily (MFS) profile
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Phosphoadenosine phosphosulphate reductase
Beta-lactamase-inhibitor-like PepSY-like domain-containing protein
RNA binding; important for wobble base 34 recognition
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Involved in tetramerization or stability of the tetramer
S-adenosylmethionine-dependent methyltransferase
Cation-transporting P-type ATPase N-terminal
Cytochrome P460 domain-containing protein
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Major facilitator superfamily associated
Outer membrane protein assembly factor BamB
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Alginate export domain-containing protein
Membrane fusion protein biotin-lipoyl like
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Polysaccharide biosynthesis protein C-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Lysidine-tRNA(Ile) synthetase C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Tryptophan synthase beta chain-like PALP
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Type 4 fimbrial biogenesis protein PilX N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Aminoacyl-transfer RNA synthetases class-II family profile
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Cytochrome oxidase subunit II copper A binding
Urease accessory protein UreH-like transmembrane
ATP synthase F1 complex delta/epsilon subunit N-terminal
Glycogen debranching enzyme bacterial and archaeal type N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Small ribosomal subunit protein uS4 N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glycine zipper 2TM domain-containing protein
RNA 2-O ribose methyltransferase substrate binding
Glucose-methanol-choline oxidoreductase N-terminal
Siroheme decarboxylase AsnC-like ligand binding
Carbamoyl-phosphate synthase small subunit N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
RND efflux pump membrane fusion protein barrel-sandwich
Flagellar motor switch protein FliN-like C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Ribose-phosphate pyrophosphokinase N-terminal
DNA mismatch repair proteins mutS family
Outer membrane protein beta-barrel domain-containing protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Exonuclease VII large subunit C-terminal
Survival protein SurE-like phosphatase/nucleotidase
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Cytochrome oxidase subunit II transmembrane region profile
Gamma-glutamylcyclotransferase AIG2-like
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Gly-cisPro motif, important for rejection of L-amino acids
Penicillin-binding protein transpeptidase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Replication-associated protein G2P N-terminal
Anthranilate synthase component I N-terminal
Lytic transglycosylase superhelical linker
N6 adenine-specific DNA methyltransferase N-terminal
Superoxide dismutase copper/zinc binding
TonB-dependent receptor-like beta-barrel
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
RNA polymerase sigma factor 70 region 4 type 2
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Bacterial type II secretion system protein E
Glycosyltransferase subfamily 4-like N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Rap1a immunity protein domain-containing protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Important for autoinhibition of adenylyltransferase activity
Peptide methionine sulphoxide reductase MsrA
UDP N-acetylglucosamine O-acyltransferase C-terminal
Bacterial transcription activator effector binding
Cytochrome b561 bacterial/Ni-hydrogenase
Type I restriction modification DNA specificity
Putative beta-barrel assembly-enhancing protease
N-end rule aminoacyl transferase C-terminal
L,D-transpeptidase catalytic domain-containing protein
Conserved virulence factor B-like winged helix
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Methylene-tetrahydromethanopterin dehydrogenase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
RlpA-like protein double-psi beta-barrel
Large ribosomal subunit protein uL2 C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Cytochrome c-type biogenesis protein CcmF C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
May play a role in metal incorporation in vivo
Polymerase/histidinol phosphatase N-terminal
Plays an important role in substrate specificity
ABC-type uncharacterised transport system
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Interaction with polymerase core subunit RpoC
Glycine-zipper-containing OmpA-like membrane
Glycine-zipper-containing OmpA-like membrane domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Cytochrome C biogenesis protein transmembrane
Glycosyl transferase family 3 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Pyruvate dehydrogenase E1 component middle
Could play a key role in the communication between the regulatory and the substrate sites
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Peptidase M43 pregnancy-associated plasma-A
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
DNA polymerase III delta subunit C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
HicB-like antitoxin of toxin-antitoxin system
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Right handed beta helix domain-containing protein
Schiff-base intermediate with substrate; via pyruvic acid
Arginine decarboxylase C-terminal helical
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Signal transduction histidine kinase internal region
Positions MEP for the nucleophilic attack
Solute-binding protein family 3/N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
NIF system FeS cluster assembly NifU N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
CRISPR-associated protein Cas6 C-terminal
Large ribosomal subunit protein uL15/eL18
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Large ribosomal subunit protein uL6 alpha-beta
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Mechanosensitive ion channel inner membrane
Glucosamine/galactosamine-6-phosphate isomerase
Polysaccharide biosynthesis protein CapD-like
ATP-grasp fold succinyl-CoA synthetase-type
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Ribonucleotide reductase large subunit C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
RNA polymerase sigma factor 54 DNA-binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Phosphoethanolamine transferase N-terminal
Glutamate synthase alpha subunit C-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Bacterial OB-fold domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
6-phosphogluconate dehydrogenase C-terminal
Disulphide bond isomerase DsbC/G N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Type 2A encapsulin shell protein SrpI-like
Important for interaction with partner proteins
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Antitoxin Xre/MbcA/ParS-like toxin-binding
PhoD-like phosphatase metallophosphatase
Prokaryotic-type class I peptide chain release factors
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Glycosyl hydrolase family 30 beta sandwich
Tetrahydrodipicolinate-N-succinyltransferase chain A
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Pyrimidine nucleoside phosphorylase C-terminal
Important for substrate binding and specificity
Aminoacyl-tRNA synthetase class I anticodon-binding
SUF system FeS cluster assembly SufBD N-terminal
Prepilin type IV endopeptidase peptidase
Resolvase/invertase-type recombinase catalytic
Required for dimer formation and molybdate binding
Diiron non-heme beta-hydroxylase N-terminal
CRISPR-associated protein Cmr2 N-terminal
Haem-binding uptake Tiki superfamily ChaN domain-containing protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Reversibly protonated during proton transport
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Flagellar assembly protein FliH/Type III secretion system HrpE
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Chromosomal replication initiator DnaA C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
DNA polymerase III subunit delta C-terminal
Inner membrane protein YgaP-like transmembrane
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Putative regulatory protein FmdB Zinc ribbon
Type VI secretion system IcmF C-terminal
Methanol dehydrogenase [cytochrome c] subunit 2
Sodium/calcium exchanger membrane region
Cysteine sulfenic acid (-SOH) intermediate
RNA polymerase sigma factor 54 core-binding
Nucleophile; cysteine thiosulfonate intermediate
Outer membrane protein assembly factor BamC
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Pseudouridine synthase I TruA alpha/beta
DNA-directed DNA polymerase family A palm
Required for zinc-mediated homotetramerization and catalytic activity
DNA-directed RNA polymerase RpoA/D/Rpb3-type
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Carboxypeptidase regulatory-like domain-containing protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
RNA 3'-terminal phosphate cyclase insert
Thiol:disulfide interchange protein DsbD
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Lipocalin-like domain-containing protein
Gamma-butyrobetaine hydroxylase-like N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
ATP-dependent DNA helicase RecG C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Translation elongation factor P/YeiP central
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
DNA replication/recombination mediator RecO N-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Release factor glutamine methyltransferase N-terminal