Tryptophan synthase beta chain-like PALP
Phosphomannose isomerase type I catalytic
Phosphomannose isomerase type I helical insertion
Interaction with polymerase core subunit RpoC
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Bacterial type II secretion system protein E
Carboxypeptidase regulatory-like domain-containing protein
TonB-dependent receptor-like beta-barrel
Large ribosomal subunit protein uL2 C-terminal
Flagellar motor switch protein FliN-like C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
YbaK/aminoacyl-tRNA synthetase-associated
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Large ribosomal subunit protein uL6 alpha-beta
Disulphide bond isomerase DsbC/G N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Peptidase M12A domain-containing protein
Dinitrogenase iron-molybdenum cofactor biosynthesis
Type II secretion system protein GspI C-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Aerolysin family beta-barrel pore-forming toxin
Heme-copper oxidase subunit III family profile
Gly-cisPro motif, important for rejection of L-amino acids
Gfo/Idh/MocA-like oxidoreductase N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Peptide methionine sulphoxide reductase MsrA
Prokaryotic-type class I peptide chain release factors
N-end rule aminoacyl transferase C-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Survival protein SurE-like phosphatase/nucleotidase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
DNA-directed DNA polymerase family A palm
Pseudouridine synthase I TruA alpha/beta
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Transposase IS116/IS110/IS902 C-terminal
Outer membrane protein assembly factor BamD
Could play a key role in the communication between the regulatory and the substrate sites
DNA polymerase III subunit delta C-terminal
Major facilitator superfamily (MFS) profile
RNA polymerase sigma factor 70 region 4 type 2
Pyridoxamine 5'-phosphate oxidase putative
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein bL25 L25
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Aminoacyl-transfer RNA synthetases class-II family profile
Outer membrane protein beta-barrel domain-containing protein
Glycine cleavage T-protein C-terminal barrel
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Phosphocysteine intermediate; for EIIB activity
Mandelate racemase/muconate lactonizing enzyme C-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
DNA replication/recombination mediator RecO N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glycosyl transferase family 3 N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Arginine decarboxylase C-terminal helical
Glucose-methanol-choline oxidoreductase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Sugar fermentation stimulation protein C-terminal
NIF system FeS cluster assembly NifU N-terminal
Cob(I)alamin adenosyltransferase N-terminal
Methylguanine DNA methyltransferase ribonuclease-like
S-adenosyl-L-homocysteine hydrolase NAD binding
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Dystroglycan-type cadherin-like domain-containing protein
Choloylglycine hydrolase/NAAA C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Electron transfer via tryptophanyl radical
Beta-hexosaminidase bacterial type N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Important for beta-aspartyl-AMP intermediate formation
Cysteine sulfenic acid (-SOH) intermediate
Glucosamine/galactosamine-6-phosphate isomerase
Flagellar assembly protein FliH/Type III secretion system HrpE
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
ABC-type glycine betaine transport system substrate-binding
Sodium symporter small subunit predicted
Helix-hairpin-helix DNA-binding motif class 1
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Chitobiase/beta-hexosaminidases N-terminal
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Nucleoside-specific channel-forming protein, Tsx
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Chromosome partition protein MukF C-terminal
Chromosome partition protein MukF middle
Chromosome partition protein MukF winged-helix
UDP N-acetylglucosamine O-acyltransferase C-terminal
High potential iron-sulfur proteins family profile
Putative ATP-dependent zinc protease domain-containing protein
Organic solvent tolerance-like N-terminal
Negative modulator of initiation of replication SeqA N-terminal
Replication modulator SeqA C-terminal DNA-binding
Polysaccharide chain length determinant N-terminal
Beta-lactamase-related domain-containing protein
Small ribosomal subunit protein uS4 N-terminal
Important for substrate binding and specificity
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Polymerase/histidinol phosphatase N-terminal
Small-conductance mechanosensitive channel
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
For 3-hydroxyacyl-CoA dehydrogenase activity
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Outer membrane protein assembly factor BamA
Schiff-base intermediate with acetaldehyde
Important for interaction with partner proteins
Phosphatidic acid phosphatase type 2/haloperoxidase
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Bacterial OB-fold domain-containing protein
Interacts with tRNA; defines subfamily-specific binding signature
DnaJ homologue subfamily C member 28 conserved
Non-canonical purine NTP phosphatase/PRRC1
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Positions MEP for the nucleophilic attack
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Rap1a immunity protein domain-containing protein
Membrane fusion protein biotin-lipoyl like
Major facilitator superfamily associated
Bacterial virulence factor lipase N-terminal
SUF system FeS cluster assembly SufBD N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Acyl-ester intermediate; for transpeptidase activity
Penicillin-binding protein transpeptidase
Proton donor; for transglycosylase activity
CD-NTase associated protein 4-like DNA endonuclease
Exonuclease VII large subunit C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Glycoside-hydrolase family GH114 TIM-barrel
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Alpha-1,6-glucosidases pullulanase-type C-terminal
Glycoside hydrolase family 13 N-terminal
Pullulanase carbohydrate-binding module 41
Solitary outer membrane autotransporter beta-barrel
Solitary outer membrane autotransporter beta-barrel domain-containing protein
Thymidylate synthase/dCMP hydroxymethylase
NIF system FeS cluster assembly NifU C-terminal
Reversibly protonated during proton transport
Type III secretion system flagellar brake protein YcgR PilZN
Flagellar hook-length control protein-like C-terminal
Transglycosylase SLT domain-containing protein
Chalcone isomerase domain-containing protein
Tellurite resistance methyltransferase TehB-like
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Glycine zipper domain-containing protein
ATP synthase F1 complex delta/epsilon subunit N-terminal
Release factor glutamine methyltransferase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Lipopolysaccharide export system protein LptA
Gamma-glutamylcyclotransferase AIG2-like
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Chromosomal replication initiator DnaA C-terminal
Plays an important role in discriminating NADH against NADPH
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Plays an important role in substrate specificity
Membrane insertase YidC/Oxa/ALB C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
S-adenosylmethionine-dependent methyltransferase
TRAP C4-dicarboxylate transport system permease DctM subunit
Threonine/serine exporter-like N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Involved in allosteric activation by GTP
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Translation elongation factor P/YeiP central
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Periplasmic nitrate reductase, electron transfer subunit
Schiff-base intermediate with substrate; via pyruvic acid
Phosphate ABC transporter substrate-binding protein
Carbamoyl-phosphate synthase small subunit N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Type II secretion system protein GspC N-terminal
Resolvase/invertase-type recombinase catalytic
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Phosphoethanolamine transferase N-terminal
Type II secretion system pilot lipoprotein GspS-beta
Putative beta-barrel assembly-enhancing protease
Phosphotransferase system enzyme I N-terminal
Replication initiator protein RctB central region
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Ysc84 actin-binding domain-containing protein
Homogentisate 1,2-dioxygenase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Nitrite/Sulfite reductase ferredoxin-like
4'-phosphopantetheinyl transferase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Alanyl-transfer RNA synthetases family profile
RNA methyltransferase SpoU/TrmH type C-terminal
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Large ribosomal subunit protein uL15/eL18
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Bacterial bifunctional deaminase-reductase C-terminal
RNA binding; important for wobble base 34 recognition
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
DNA mismatch repair proteins mutS family
Lysozyme inhibitor LprI N-terminal domain-containing protein
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Essential for prephenate dehydratase activity
Aminoacyl-tRNA synthetase class I anticodon-binding
Polysaccharide biosynthesis protein CapD-like
Alpha-glycerophosphate oxidase C-terminal
Bacterial surface antigen (D15) domain-containing protein
Anthranilate synthase component I N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Autoinducer 2-binding periplasmic protein LuxP
Appears to be important in orienting the phosphate for catalysis
O-(3'-phospho-DNA)-tyrosine intermediate
Ribosomal RNA adenine methylase transferase N-terminal
ABC-type transport auxiliary lipoprotein component
Glutathionylspermidine synthase pre-ATP-grasp-like
Threonine-rich inner membrane protein GfcA
DNA polymerase III delta subunit C-terminal
Important for autoinhibition of adenylyltransferase activity
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
NADH-rubredoxin oxidoreductase C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Capsule biosynthesis GfcC-like C-terminal
Capsule biosynthesis GfcC-like N-terminal
Integral membrane protein YccS N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Acetyl-CoA hydrolase/transferase C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Prepilin type IV endopeptidase peptidase
Cation-transporting P-type ATPase N-terminal
Carboxylesterase type B domain-containing protein
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Molybdopterin cofactor biosynthesis C (MoaC)
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle