Pyridoxamine 5'-phosphate oxidase putative
Alpha-glycerophosphate oxidase C-terminal
Prokaryotic-type class I peptide chain release factors
Nitrile hydratase alpha /Thiocyanate hydrolase gamma
Major facilitator superfamily (MFS) profile
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Activator of Hsp90 ATPase homologue 1-like C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Polymerase/histidinol phosphatase N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-145)
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Putative regulatory protein FmdB Zinc ribbon
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Putative oxidoreductase/dehydrogenase Rossmann-like
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Ribulose bisphosphate carboxylase small subunit
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Phosphatidylglycerol lysyltransferase C-terminal
Peptide methionine sulphoxide reductase MsrA
AMP-activated protein kinase glycogen-binding
Chromosomal replication initiator DnaA C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Cytochrome b/b6 N-terminal region profile
Essential for prephenate dehydratase activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Alpha-D-phosphohexomutase alpha/beta/alpha
Peptidase S9 prolyl oligopeptidase catalytic
Glycosyltransferase subfamily 4-like N-terminal
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Bacterial bifunctional deaminase-reductase C-terminal
Periplasmic binding protein domain-containing protein
Reversibly protonated during proton transport
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Pyruvate phosphate dikinase AMP/ATP-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Glycine cleavage T-protein C-terminal barrel
Conserved hypothetical protein CHP02679 N terminus
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Poly-beta-hydroxybutyrate polymerase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Transposase IS116/IS110/IS902 C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Helix-hairpin-helix DNA-binding motif class 1
Cell wall-active antibiotics response LiaF-like C-terminal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Diacylglycerol glucosyltransferase N-terminal
DNA replication/recombination mediator RecO N-terminal
Methylene-tetrahydrofolate reductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
ATP synthase F1 complex delta/epsilon subunit N-terminal
Penicillin-binding protein transpeptidase
SsuA/THI5-like domain-containing protein
Phosphomannose isomerase type I catalytic
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Putative adhesin domain-containing protein
Solute-binding protein family 3/N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Positions MEP for the nucleophilic attack
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
NADH-rubredoxin oxidoreductase C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
SUF system FeS cluster assembly SufBD N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glucosamine/galactosamine-6-phosphate isomerase
Erythromycin biosynthesis protein CIII-like central
Erythromycin biosynthesis protein CIII-like central domain-containing protein
Large ribosomal subunit protein uL2 C-terminal
5-glutamyl coenzyme A thioester intermediate
Cell envelope-related transcriptional attenuator
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Membrane fusion protein biotin-lipoyl like
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Homogentisate 1,2-dioxygenase C-terminal
ATP-dependent DNA helicase RecG C-terminal
Ribulose bisphosphate carboxylase large chain
Pyruvate dehydrogenase E1 component middle
Endoribonuclease L-PSP/chorismate mutase-like
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Important for beta-aspartyl-AMP intermediate formation
Glycosyl transferase family 28 C-terminal
DNA primase/polymerase bifunctional N-terminal
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Removed in mature form; by autocatalysis
Glutathionylspermidine synthase pre-ATP-grasp-like
6-phosphogluconate dehydrogenase C-terminal
PhoD-like phosphatase metallophosphatase
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Histidine-specific methyltransferase SAM-dependent
Tryptophan synthase beta chain-like PALP
Anti-sigma-D factor RsdA sigma factor binding region
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Phosphoadenosine phosphosulphate reductase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Translation elongation factor P/YeiP central
Release factor glutamine methyltransferase N-terminal
Exonuclease VII large subunit C-terminal
Small ribosomal subunit protein uS4 N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Transcription regulator AsnC/Lrp ligand binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
CDP-alcohol phosphatidyltransferase C-terminal
Glycosyltransferase family 28 N-terminal
RNA 2-O ribose methyltransferase substrate binding
Lysyl-tRNA synthetase N-terminal transmembrane region
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Bacterial transcription activator effector binding
N,N-dimethylformamidase beta subunit-like C-terminal
Cytochrome C biogenesis protein transmembrane
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Proton acceptor; for glutaminase activity
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Could play a key role in the communication between the regulatory and the substrate sites
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Cation-transporting P-type ATPase N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Survival protein SurE-like phosphatase/nucleotidase
DNA topoisomerase I catalytic core eukaryotic-type
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Schiff-base intermediate with substrate; via topaquinone
Nucleophile; cysteine thiosulfonate intermediate
Anthranilate synthase component I N-terminal
Alanyl-transfer RNA synthetases family profile
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-108)
Nicotinate phosphoribosyltransferase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Threonine/serine exporter-like N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Plays an important role in substrate specificity
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Adenosylcobinamide-GDP ribazoletransferase
Large ribosomal subunit protein uL6 alpha-beta
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Inosine/uridine-preferring nucleoside hydrolase
Resolvase/invertase-type recombinase catalytic
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Transcription elongation factor GreA/GreB C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Peptidase M1 membrane alanine aminopeptidase
Acetyl-CoA hydrolase/transferase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Quinolinate phosphoribosyl transferase N-terminal
Sporulation transcription regulator WhiA N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Resuscitation-promoting factor core lysozyme-like
Glucose-methanol-choline oxidoreductase C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
NIF system FeS cluster assembly NifU N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Superoxide dismutase copper/zinc binding
Superoxide dismutase copper/zinc binding domain-containing protein
Involved in ionization of N3 of dUMP, leading to its activation
Phosphatidic acid phosphatase type 2/haloperoxidase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glyoxalase/fosfomycin resistance/dioxygenase
Acetylserotonin O-methyltransferase dimerisation
Vanillate O-demethylase oxygenase-like C-terminal catalytic
Large ribosomal subunit protein uL15/eL18
O-(3'-phospho-DNA)-tyrosine intermediate
Phosphatidate phosphatase APP1 catalytic
Lactate utilization protein B C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Methionyl-tRNA synthetase anticodon-binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Interaction with polymerase core subunit RpoC
Cysteine sulfenic acid (-SOH) intermediate
Quercetin 2,3-dioxygenase C-terminal cupin
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
ABC-type glycine betaine transport system substrate-binding
Transition state stabilizer; via amide nitrogen