Cytochrome C biogenesis protein transmembrane
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Schiff-base intermediate with substrate; via pyruvic acid
Gfo/Idh/MocA-like oxidoreductase N-terminal
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
FAD-dependent oxidoreductase 2 FAD binding
Sodium/calcium exchanger membrane region
Major facilitator superfamily (MFS) profile
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
ABC transporter substrate-binding protein PnrA-like
Transition state stabilizer; via amide nitrogen
Formamidopyrimidine-DNA glycosylase catalytic
1-phosphatidylinositol phosphodiesterase
Phosphatidylinositol-specific phospholipase C X
Transcription regulator AsnC/Lrp ligand binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
SGNH hydrolase-type esterase domain-containing protein
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
DNA primase/polymerase bifunctional N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Phosphomannose isomerase type I catalytic
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Essential for prephenate dehydratase activity
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
Carbamoyl-phosphate synthase small subunit N-terminal
Solute-binding protein family 3/N-terminal
Important for beta-aspartyl-AMP intermediate formation
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Heme-copper oxidase subunit III family profile
Aromatic amino acid beta-eliminating lyase/threonine aldolase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Peptide methionine sulphoxide reductase MsrA
Glucosamine/galactosamine-6-phosphate isomerase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
N-acetylneuraminic acid synthase N-terminal
Leucine-binding protein domain-containing protein
Schiff-base intermediate with D-ribose 5-phosphate
Erythromycin biosynthesis protein CIII-like central
Phosphatidic acid phosphatase type 2/haloperoxidase
Pyrimidine nucleoside phosphorylase C-terminal
Polymerase/histidinol phosphatase N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Positions MEP for the nucleophilic attack
Plays an important role in substrate specificity
Alpha-D-phosphohexomutase alpha/beta/alpha
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Aminoacyl-transfer RNA synthetases class-II family profile
CobB/CobQ-like glutamine amidotransferase
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Cysteine sulfenic acid (-SOH) intermediate
Beta-hexosaminidase bacterial type N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Prokaryotic-type class I peptide chain release factors
Pyruvate dehydrogenase E1 component middle
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
NADH-rubredoxin oxidoreductase C-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Tryptophan synthase beta chain-like PALP
Large ribosomal subunit protein uL2 C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
LPXTG cell wall anchor domain-containing protein
Ribose-phosphate pyrophosphokinase N-terminal
Penicillin-binding protein transpeptidase
Protein O-mannosyl-transferase C-terminal four TM
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Helix-hairpin-helix DNA-binding motif class 1
Glycosyl transferase family 3 N-terminal
DNA replication/recombination mediator RecO N-terminal
Putative regulatory protein FmdB Zinc ribbon
RNA polymerase sigma factor 70 region 4 type 2
Phosphocysteine intermediate; for EIIB activity
Bacterial type II secretion system protein E
Translation elongation factor P/YeiP central
Adaptive response protein AidB N-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Peptidase M1 membrane alanine aminopeptidase
Acetylserotonin O-methyltransferase dimerisation
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Sporulation transcription regulator WhiA N-terminal
HTH-type transcriptional repressor KstR2 C-terminal
PhoD-like phosphatase metallophosphatase
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glutathionylspermidine synthase pre-ATP-grasp-like
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Gamma-glutamylcyclotransferase AIG2-like
Ricin B lectin domain-containing protein
Reversibly protonated during proton transport
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Large ribosomal subunit protein uL15/eL18
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Cell envelope-related transcriptional attenuator
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Threonine/serine exporter-like N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Alpha-glycerophosphate oxidase C-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-96)
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-119)
Removed in mature form; by autocatalysis
Styrene monooxygenase StyA putative substrate binding
Small ribosomal subunit protein uS4 N-terminal
NIF system FeS cluster assembly NifU N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
4'-phosphopantetheinyl transferase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Activator of Hsp90 ATPase homologue 1-like C-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
2-oxoacid dehydrogenase acyltransferase catalytic
Important for substrate specificity; cannot use PPi as phosphoryl donor
Phosphoribosylformylglycinamidine synthase linker
Exonuclease VII large subunit C-terminal
Glycine cleavage T-protein C-terminal barrel
Anthranilate synthase component I N-terminal
Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase C-terminal
Proton acceptor; for glutaminase activity
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Histidine-specific methyltransferase SAM-dependent
DnaJ homologue subfamily C member 28 conserved
ATP synthase F1 complex delta/epsilon subunit N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Methylguanine DNA methyltransferase ribonuclease-like
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Phosphotransferase system enzyme I N-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
NADH:flavin oxidoreductase/NADH oxidase N-terminal
N,N-dimethylformamidase beta subunit-like C-terminal
Heat-inducible transcription repressor HrcA C-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Cytochrome bc1 complex cytochrome c subunit
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
NADH:ubiquinone oxidoreductase 30kDa subunit
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
DNA-directed DNA polymerase family A palm
Gram-positive cocci surface proteins LPxTG
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Ionotropic glutamate receptor C-terminal
RNA 2-O ribose methyltransferase substrate binding
Cytochrome oxidase subunit II copper A binding
Tat pathway signal sequence domain protein
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Squalene cyclase C-terminal domain-containing protein
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
SUF system FeS cluster assembly SufBD N-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Myo-inositol-1-phosphate synthase GAPDH-like
Involved in allosteric activation by GTP
Acyltransferase MbtK/IucB-like conserved
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
YbaK/aminoacyl-tRNA synthetase-associated
Endoribonuclease L-PSP/chorismate mutase-like
Large ribosomal subunit protein uL30-like ferredoxin-like fold
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
6-phosphogluconate dehydrogenase C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glycoside-hydrolase family GH114 TIM-barrel
Molybdopterin cofactor biosynthesis C (MoaC)
Shikimate dehydrogenase substrate binding N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Chromosomal replication initiator DnaA C-terminal
Probable subtilase-type protease inhibitor