Aminoacyl-transfer RNA synthetases class-II family profile
Cytochrome c-type biogenesis protein CcmF C-terminal
Type II secretion system protein GspG C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Arabinogalactan endo-beta-1,4-galactanase
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Peptidase S9 prolyl oligopeptidase catalytic
RNA polymerase sigma factor 70 region 4 type 2
tRNA pseudouridylate synthase B C-terminal
SUF system FeS cluster assembly SufBD N-terminal
Trigger factor ribosome-binding bacterial
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Manganese/iron superoxide dismutase C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Putative auto-transporter adhesin head GIN
Membrane insertase YidC/Oxa/ALB C-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Glycosyltransferase subfamily 4-like N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
Pyruvate phosphate dikinase AMP/ATP-binding
Alanyl-transfer RNA synthetases family profile
Ribose-phosphate pyrophosphokinase N-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Secretin/TonB short N-terminal domain-containing protein
Prepilin type IV endopeptidase peptidase
Acyl-CoA dehydrogenase/oxidase N-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Schiff-base intermediate with substrate; via pyruvic acid
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Glycine cleavage T-protein C-terminal barrel
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Beta-hexosaminidase bacterial type N-terminal
Glycosyl-hydrolase family 116 N-terminal
Glycosyl-hydrolase family 116 catalytic region
Phosphoadenosine phosphosulphate reductase
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Carbamoyl-phosphate synthase small subunit N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Bacterial transcription activator effector binding
Alpha glucuronidase N-terminal domain-containing protein
Tryptophan synthase beta chain-like PALP
Large ribosomal subunit protein bL9 C-terminal
Glucose-6-phosphate isomerase prokaryote
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Moybdenum cofactor oxidoreductase dimerisation
S-adenosyl-L-homocysteine hydrolase NAD binding
Myo-inositol-1-phosphate synthase GAPDH-like
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Bacterial type II secretion system protein E
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Major facilitator superfamily (MFS) profile
Formamidopyrimidine-DNA glycosylase catalytic
Heat-inducible transcription repressor HrcA C-terminal
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Histidine-specific methyltransferase SAM-dependent
Na+-translocating membrane potential-generating system MpsC
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Heme-copper oxidase subunit III family profile
Peptidase M1 membrane alanine aminopeptidase
Butirosin biosynthesis protein H N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Polysaccharide chain length determinant N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Lipocalin-like domain-containing protein
DNA topoisomerase I catalytic core eukaryotic-type
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Cation-transporting P-type ATPase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Conserved virulence factor B-like winged helix
Ribosomal RNA small subunit methyltransferase E methyltransferase
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
PrcB C-terminal domain-containing protein
Outer membrane protein beta-barrel domain-containing protein
Glycoside hydrolase GH146 substrate-binding
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Chromosomal replication initiator protein DnaA
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Pyridoxamine 5'-phosphate oxidase putative
O-(5'-phospho-DNA)-tyrosine intermediate
Peptidase M10 metallopeptidase domain-containing protein
Glycoside hydrolase family 42 N-terminal
Putative regulatory protein FmdB Zinc ribbon
Glutathionylspermidine synthase pre-ATP-grasp-like
Membrane fusion protein biotin-lipoyl like
Bacterial alpha-L-rhamnosidase N-terminal
Fibronectin type-III domain-containing protein
Sodium/calcium exchanger membrane region
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
Penicillin-binding protein transpeptidase
N6 adenine-specific DNA methyltransferase N-terminal
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Copper amine oxidase-like N-terminal domain-containing protein
Plays an important role in substrate specificity
Pyridine nucleotide-disulphide oxidoreductase dimerisation
DNA-directed DNA polymerase family A palm
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Bacterial DNA polymerase III alpha subunit NTPase
DNA polymerase helix-hairpin-helix motif
Transposase IS116/IS110/IS902 C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Glycoside hydrolase family 31 N-terminal
Glycosyl hydrolase family 98 putative carbohydrate-binding module
DNA replication/recombination mediator RecO N-terminal
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Lysidine-tRNA(Ile) synthetase C-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Shikimate dehydrogenase substrate binding N-terminal
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Glycosyl transferase family 3 N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
RND efflux pump membrane fusion protein barrel-sandwich
Essential for prephenate dehydratase activity
NADH:ubiquinone oxidoreductase 30kDa subunit
6-phosphogluconate dehydrogenase C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Cytochrome oxidase subunit II copper A binding
Saccharopine dehydrogenase-like C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
ABC transporter substrate-binding protein PnrA-like
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
RNA 3'-terminal phosphate cyclase insert
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Blue (type 1) copper domain-containing protein
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Carbohydrate-binding domain-containing protein
Nucleophile; cysteine thiosulfonate intermediate
Lactate utilization protein B C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Alpha galactosidase C-terminal beta sandwich
Haem-binding uptake Tiki superfamily ChaN
Pyrroline-5-carboxylate reductase catalytic N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Small ribosomal subunit protein uS4 N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Anthranilate synthase component I N-terminal
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
Alpha-D-phosphohexomutase alpha/beta/alpha
ATP synthase F1 complex delta/epsilon subunit N-terminal
Calcineurin-like phosphoesterase domain-containing protein
Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-? in acceptor proteins)
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Periplasmic copper-binding protein NosD beta helix
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Beta-xylosidase C-terminal Concanavalin A-like
Molybdopterin cofactor biosynthesis C (MoaC)
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
3-keto-disaccharide hydrolase domain-containing protein