Terminase large subunit-like endonuclease
Carbamoyl-phosphate synthase small subunit N-terminal
Interaction with polymerase core subunit RpoC
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Phosphate ABC transporter substrate-binding protein
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Flagellar basal body rod protein N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Mandelate racemase/muconate lactonizing enzyme C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Heme-copper oxidase subunit III family profile
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Major facilitator superfamily (MFS) profile
Phosphatidic acid phosphatase type 2/haloperoxidase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
PHA accumulation regulator DNA-binding N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
TRAP C4-dicarboxylate transport system permease DctM subunit
Seems to be a necessary countercharge to the potassium cations
Anthranilate synthase component I N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Solute-binding protein family 3/N-terminal
Polymerase/histidinol phosphatase N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Glycosyltransferase subfamily 4-like N-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Flagellar basal-body/hook protein C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Moybdenum cofactor oxidoreductase dimerisation
Reversibly protonated during proton transport
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Flagellar hook-length control protein-like C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Electron transfer flavoprotein alpha subunit C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Nitrite/Sulfite reductase ferredoxin-like
DNA replication/recombination mediator RecO N-terminal
CobB/CobQ-like glutamine amidotransferase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Membrane fusion protein biotin-lipoyl like
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
TonB-dependent receptor-like beta-barrel
Serine/threonine specific protein phosphatases
Mannose-6-phosphate isomerase type II C-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Secretin/TonB short N-terminal domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
DNA polymerase III delta subunit C-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
O-(3'-phospho-DNA)-tyrosine intermediate
Outer-membrane lipoprotein Wza C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Pyridoxamine 5'-phosphate oxidase putative
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
O-(5'-phospho-DNA)-tyrosine intermediate
Glycosyl transferase family 28 C-terminal
Important for interaction with partner proteins
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Bacteriophage tail tape measure C-terminal
Bacteriophage tail tape measure N-terminal
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
DNA-directed DNA polymerase family A palm
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Peptide methionine sulphoxide reductase MsrA
Outer membrane protein assembly factor BamB
Plays an important role in discriminating NADH against NADPH
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Gly-cisPro motif, important for rejection of L-amino acids
Restriction system protein Mrr-like N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
N-end rule aminoacyl transferase C-terminal
Plays an important role in substrate specificity
Glucose-methanol-choline oxidoreductase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Translation elongation factor P/YeiP central
S-adenosylmethionine-dependent methyltransferase
Glycosyltransferase family 28 N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Phosphocysteine intermediate; for EIIB activity
Erythronate-4-phosphate dehydrogenase dimerisation
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Bacterial type II secretion system protein E
Guanylate kinase/L-type calcium channel beta subunit
MmyB-like transcription regulator ligand binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Phosphoadenosine phosphosulphate reductase
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Capsule biosynthesis GfcC-like C-terminal
Capsule biosynthesis GfcC-like C-terminal domain-containing protein
Important for substrate binding and specificity
Aminoacyl-tRNA synthetase class I anticodon-binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop
Penicillin-binding protein transpeptidase
Shikimate dehydrogenase substrate binding N-terminal
Flagellar motor switch protein FliN-like C-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Inosine/uridine-preferring nucleoside hydrolase
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
ABC-type glycine betaine transport system substrate-binding
Alanyl-transfer RNA synthetases family profile
6-phosphogluconate dehydrogenase C-terminal
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glycine cleavage T-protein C-terminal barrel
Integral membrane protein YccS N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Na+/H+ antiporter MnhB subunit-related protein
RNA polymerase sigma factor 70 region 4 type 2
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Thymidylate synthase/dCMP hydroxymethylase
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Tryptophan synthase beta chain-like PALP
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Positions MEP for the nucleophilic attack
Alginate export domain-containing protein
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Ionotropic glutamate receptor C-terminal
Trimeric autotransporter adhesin YadA-like C-terminal membrane anchor
Trimeric autotransporter adhesin YadA-like C-terminal membrane anchor domain-containing protein
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Formamidopyrimidine-DNA glycosylase catalytic
Superoxide dismutase copper/zinc binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Alpha-D-phosphohexomutase alpha/beta/alpha
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Type I restriction modification DNA specificity
Bacterial bifunctional deaminase-reductase C-terminal
Electron transfer via tryptophanyl radical
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Arginine decarboxylase C-terminal helical
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
DNA polymerase III subunit delta C-terminal
Lactate utilization protein B C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Prokaryotic-type class I peptide chain release factors
Polysaccharide biosynthesis protein C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Release factor glutamine methyltransferase N-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Disulphide bond isomerase DsbC/G N-terminal
Exonuclease VII large subunit C-terminal
Interacts with tRNA; defines subfamily-specific binding signature
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Survival protein SurE-like phosphatase/nucleotidase
Cytochrome b561 bacterial/Ni-hydrogenase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Lysidine-tRNA(Ile) synthetase C-terminal
Sodium/calcium exchanger membrane region
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Outer membrane protein OmpA-like transmembrane
Outer membrane protein OmpA-like transmembrane domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
NADH:ubiquinone oxidoreductase-like 20kDa subunit
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
PhoD-like phosphatase metallophosphatase
Small ribosomal subunit protein uS4 N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Ribosomal RNA adenine methylase transferase N-terminal
Chromosomal replication initiator DnaA C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
UDP N-acetylglucosamine O-acyltransferase C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Large ribosomal subunit protein uL2 C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Negative regulator for alginate biosynthesis MucB
ABC transporter substrate-binding protein
Polysaccharide chain length determinant N-terminal
Large ribosomal subunit protein uL15/eL18
Poly-beta-hydroxybutyrate polymerase N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Conserved virulence factor B-like winged helix
Histidine-specific methyltransferase SAM-dependent
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
NIF system FeS cluster assembly NifU C-terminal
Alpha-glycerophosphate oxidase C-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
ATP synthase F1 complex delta/epsilon subunit N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Cysteine sulfenic acid (-SOH) intermediate
Lysozyme inhibitor LprI N-terminal domain-containing protein
Glycosyl transferase family 3 N-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal