Survival protein SurE-like phosphatase/nucleotidase
SusE outer membrane protein domain-containing protein
RNA polymerase sigma factor 70 region 4 type 2
Glycosyl transferase family 3 N-terminal
Electron transfer via tryptophanyl radical
ATP-dependent DNA helicase RecG C-terminal
TonB-dependent receptor-like beta-barrel
Peptidase M1 membrane alanine aminopeptidase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Tetrahydrodipicolinate-N-succinyltransferase chain A
Glycosyltransferase subfamily 4-like N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Major facilitator superfamily (MFS) profile
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Could be important to modulate the pK values of the two catalytic cysteine residues
DNA replication/recombination mediator RecO N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Heme-copper oxidase subunit III family profile
Lysidine-tRNA(Ile) synthetase C-terminal
Membrane fusion protein biotin-lipoyl like
Glycerophosphoryl diester phosphodiesterase membrane
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Geranylgeranylglyceryl phosphate synthase
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Ribose-phosphate pyrophosphokinase N-terminal
Outer membrane protein beta-barrel domain-containing protein
DNA topoisomerase I catalytic core eukaryotic-type
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Type I restriction modification DNA specificity
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Na+/H+ antiporter MnhB subunit-related protein
Gfo/Idh/MocA-like oxidoreductase N-terminal
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Aconitase A/isopropylmalate dehydratase small subunit swivel
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Tryptophan synthase beta chain-like PALP
Prokaryotic-type class I peptide chain release factors
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Helix-hairpin-helix DNA-binding motif class 1
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Pseudouridine synthase I TruA alpha/beta
Putative auto-transporter adhesin head GIN
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Glycoside hydrolase family 13 N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Thymidylate synthase/dCMP hydroxymethylase
RND efflux pump membrane fusion protein barrel-sandwich
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
O-(5'-phospho-DNA)-tyrosine intermediate
N-sulphoglucosamine sulphohydrolase C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Histidine-specific methyltransferase SAM-dependent
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Small ribosomal subunit protein uS4 N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Glycosyl-hydrolase 97 C-terminal oligomerisation
Ribonucleotide reductase large subunit C-terminal
General stress protein FMN-binding split barrel
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
DNA mismatch repair proteins mutS family
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Signal transduction histidine kinase internal region
Type I restriction enzyme R protein N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
TerB family tellurite resistance protein
Membrane insertase YidC/Oxa/ALB C-terminal
Penicillin-binding protein transpeptidase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Phosphoadenosine phosphosulphate reductase
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
tRNA pseudouridylate synthase B C-terminal
Ribosome maturation factor RimP N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Glycine cleavage T-protein C-terminal barrel
Carbamoyl-phosphate synthase small subunit N-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Alpha-N-acetylglucosaminidase C-terminal
Alpha-N-acetylglucosaminidase N-terminal
Alpha-N-acetylglucosaminidase tim-barrel
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Transition state stabilizer; via amide nitrogen
Glycoside hydrolase family 31 N-terminal
Translation elongation factor P/YeiP central
Secretion system C-terminal sorting domain-containing protein
Chalcone isomerase domain-containing protein
Ribonucleotide reductase large subunit N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Glycosyl hydrolase family 30 beta sandwich
Polysaccharide biosynthesis protein CapD-like
Extracellular endo-alpha-(1->5)-L-arabinanase C-terminal
Anthranilate synthase component I N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Chromosomal replication initiator DnaA C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
DNA-directed DNA polymerase family A palm
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Organic solvent tolerance-like N-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
Release factor glutamine methyltransferase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Transcription elongation factor GreA/GreB C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
CagE TrbE VirB component of type IV transporter system central
RagB/SusD family nutrient uptake outer membrane protein
Peptidase S9 prolyl oligopeptidase catalytic
Cytochrome oxidase subunit II copper A binding
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Peptide methionine sulphoxide reductase MsrA
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Alpha-glycerophosphate oxidase C-terminal
Bacterial DNA polymerase III alpha subunit NTPase
DNA polymerase helix-hairpin-helix motif
Beta-hexosaminidase bacterial type N-terminal
Polysaccharide chain length determinant N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Carboxypeptidase-like regulatory domain-containing protein
Plays an important role in substrate specificity
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
Important for beta-aspartyl-AMP intermediate formation
Transcription elongation factor GreA/GreB N-terminal
Cytochrome oxidase subunit II transmembrane region profile
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glyceraldehyde 3-phosphate dehydrogenase catalytic
Shikimate dehydrogenase substrate binding N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Homogentisate 1,2-dioxygenase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Sodium/calcium exchanger membrane region
Glycosyl hydrolase-like 10 domain-containing protein
Pyruvate dehydrogenase E1 component middle
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
O-(3'-phospho-DNA)-tyrosine intermediate
Type IX secretion system protein PorV domain-containing protein
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Alanyl-transfer RNA synthetases family profile
Glycoside hydrolase GH146 substrate-binding
NIF system FeS cluster assembly NifU C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
CarboxypepD_reg-like domain-containing protein
Reversibly protonated during proton transport
Trimeric autotransporter adhesin YadA-like head
Quercetin 2,3-dioxygenase C-terminal cupin
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ABC-type uncharacterised transport system
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Large ribosomal subunit protein uL2 C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Phosphatidate phosphatase APP1 catalytic
6-phosphogluconate dehydrogenase C-terminal
Thiamin pyrophosphokinase thiamin-binding
Putative auto-transporter adhesin head GIN domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-113)
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
RNA binding; important for wobble base 34 recognition
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
ATP-grasp fold succinyl-CoA synthetase-type
Beta-lactamase-inhibitor-like PepSY-like domain-containing protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Schiff-base intermediate with substrate; via pyruvic acid
Trigger factor ribosome-binding bacterial
Solute-binding protein family 3/N-terminal
Nicotinic acid mononucleotide adenyltransferase
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
UDP N-acetylglucosamine O-acyltransferase C-terminal
Large ribosomal subunit protein uL15/eL18
Urease accessory protein UreH-like transmembrane
Conserved virulence factor B-like winged helix
Nitrite/Sulfite reductase ferredoxin-like
Large ribosomal subunit protein uL6 alpha-beta
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Polymerase/histidinol phosphatase N-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Peptide methionine sulfoxide reductase MsrA
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Haem-binding uptake Tiki superfamily ChaN
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Glycoamylase-like domain-containing protein
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Saccharopine dehydrogenase-like C-terminal
RNA 2-O ribose methyltransferase substrate binding
Polysaccharide biosynthesis protein C-terminal
Lipocalin-like domain-containing protein
Large ribosomal subunit protein bL9 C-terminal
Lysozyme inhibitor LprI N-terminal domain-containing protein
Bacterial transcription activator effector binding
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM