DNA mismatch repair proteins mutS family
Major facilitator superfamily (MFS) profile
Cation-transporting P-type ATPase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
RNA 2-O ribose methyltransferase substrate binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Phosphotransferase system enzyme I N-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glucosamine/galactosamine-6-phosphate isomerase
Could play a key role in the communication between the regulatory and the substrate sites
Phosphatidic acid phosphatase type 2/haloperoxidase
Alpha-glycerophosphate oxidase C-terminal
Gram-positive cocci surface proteins LPxTG
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Thiamin pyrophosphokinase thiamin-binding
Cell envelope-related transcriptional attenuator
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Alanyl-transfer RNA synthetases family profile
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
NIF system FeS cluster assembly NifU N-terminal
6-phosphogluconate dehydrogenase C-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
M protein trans-acting positive regulator (MGA) HTH
M protein trans-acting positive regulator (MGA) PRD
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Helix-hairpin-helix DNA-binding motif class 1
Cell wall-active antibiotics response LiaF-like C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Tryptophan synthase beta chain-like PALP
Plays an important role in substrate specificity
Prokaryotic-type class I peptide chain release factors
Phosphotransferase system EIIB component type 2/3
Shikimate dehydrogenase substrate binding N-terminal
Penicillin-binding protein transpeptidase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Sporulation transcription regulator WhiA N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Membrane insertase YidC/Oxa/ALB C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Schiff-base intermediate with acetaldehyde
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Important for interaction with partner proteins
Small ribosomal subunit protein uS4 N-terminal
Cytochrome C biogenesis protein transmembrane
Ribose-phosphate pyrophosphokinase N-terminal
Involved in allosteric activation by GTP
Pseudouridine synthase I TruA alpha/beta
RNA binding; important for wobble base 34 recognition
S-adenosylmethionine-dependent methyltransferase
X-Prolyl dipeptidyl aminopeptidase PepX N-terminal
Polymerase/histidinol phosphatase N-terminal
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glycosyl transferase family 3 N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Schiff-base intermediate with D-ribose 5-phosphate
O-(5'-phospho-DNA)-tyrosine intermediate
Streptococcal pilin isopeptide linker domain-containing protein
Interaction with polymerase core subunit RpoC
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Translation elongation factor P/YeiP central
Exonuclease VII large subunit C-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
ABC transporter substrate-binding protein PnrA-like
DNA/pantothenate metabolism flavoprotein C-terminal
Thymidylate synthase/dCMP hydroxymethylase
Ribosomal RNA adenine methylase transferase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Phosphomannose isomerase type I catalytic
Large ribosomal subunit protein uL6 alpha-beta
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Pyrimidine nucleoside phosphorylase C-terminal
Phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease 4
Reversibly protonated during proton transport
Glycosyltransferase subfamily 4-like N-terminal
Anthranilate synthase component I N-terminal
Transcriptional coactivator p15 (PC4) C-terminal
Integron-associated effector binding protein
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Conserved virulence factor B-like winged helix
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Polysaccharide biosynthesis protein CapD-like
Carbamoyl-phosphate synthase small subunit N-terminal
Positions ribitol 5-phosphate for the nucleophilic attack
Polysaccharide biosynthesis protein C-terminal
Regulator of chromosome segregation-like C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Threonine/serine exporter-like N-terminal
Chromosomal replication initiator DnaA C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Large ribosomal subunit protein uL15/eL18
N-acetyl-beta-D-glucosaminidase N-terminal
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Tellurite resistance methyltransferase TehB-like
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Essential for prephenate dehydratase activity
Saccharopine dehydrogenase-like C-terminal
Peptidase M1 membrane alanine aminopeptidase
Bacterial type II secretion system protein E
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Polysaccharide chain length determinant N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
SUF system FeS cluster assembly SufBD N-terminal
CobB/CobQ-like glutamine amidotransferase
Transcriptional regulator TetR C-terminal Firmicutes type
DNA replication/recombination mediator RecO N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Lysidine-tRNA(Ile) synthetase C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Phosphocysteine intermediate; for EIIB activity
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha