Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Glycosyltransferase subfamily 4-like N-terminal
TonB-dependent receptor-like beta-barrel
NADH:ubiquinone oxidoreductase 30kDa subunit
Saccharopine dehydrogenase-like C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Major facilitator superfamily (MFS) profile
Disulphide bond isomerase DsbC/G N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Aminoacyl-transfer RNA synthetases class-II family profile
Large ribosomal subunit protein uL2 C-terminal
Flagellar basal body rod protein N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Solute-binding protein family 3/N-terminal
Tryptophan synthase beta chain-like PALP
TRAP C4-dicarboxylate transport system permease DctM subunit
Required for dimer formation and molybdate binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Flagellar Assembly Protein A N-terminal region
Helix-hairpin-helix DNA-binding motif class 1
Gfo/Idh/MocA-like oxidoreductase N-terminal
Large ribosomal subunit protein uL15/eL18
Bacterial type II secretion system protein E
Involved in allosteric activation by GTP
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Type I restriction modification DNA specificity
Flagella basal body P-ring formation protein FlgA
Probable endolytic peptidoglycan transglycosylase RlpA
Polymerase/histidinol phosphatase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Prepilin type IV endopeptidase peptidase
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Important for interaction with partner proteins
Penicillin-binding protein transpeptidase
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Membrane iron-sulfur containing protein FtrD-like
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Quinohemoprotein amine dehydrogenase alpha subunit haem binding domain-containing protein
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
N6 adenine-specific DNA methyltransferase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Alpha-D-phosphohexomutase alpha/beta/alpha
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Anthranilate synthase component I N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Tetratricopeptide TPR_1 repeat-containing protein
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Cytochrome c-552/4 domain-containing protein
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Putative regulatory protein FmdB Zinc ribbon
DNA mismatch repair proteins mutS family
Polysaccharide biosynthesis protein C-terminal
Na+/H+ antiporter MnhB subunit-related protein
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Flagellar hook-length control protein-like C-terminal
Flagellar basal-body/hook protein C-terminal
Plays an important role in substrate specificity
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Survival protein SurE-like phosphatase/nucleotidase
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Thiamine pyrophosphate enzyme TPP-binding
Large ribosomal subunit protein uL6 alpha-beta
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Urease accessory protein UreH-like transmembrane
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
tRNA (guanine-N(1)-)-methyltransferase C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Inner membrane protein YgaP-like transmembrane
Flagellar motor switch protein FliN-like C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Membrane insertase YidC/Oxa/ALB C-terminal
6-hydroxymethylpterin diphosphokinase MptE-like
Important for autoinhibition of adenylyltransferase activity
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Cytochrome C biogenesis protein transmembrane
Pyruvate/ketoisovalerate oxidoreductase catalytic
Class III cytochrome C domain-containing protein
Tellurite resistance methyltransferase TehB-like
Positions MEP for the nucleophilic attack
Mannose-6-phosphate isomerase type II C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Aconitase A/isopropylmalate dehydratase small subunit swivel
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Pseudouridine synthase I TruA alpha/beta
Phosphotransferase system enzyme I N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Phosphoadenosine phosphosulphate reductase
Organic solvent tolerance-like N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Lipoprotein SmpA/OmlA domain-containing protein
Prokaryotic-type class I peptide chain release factors
Type II secretion system protein GspG C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
ATP-dependent DNA helicase RecG C-terminal
EfeO-type cupredoxin-like domain-containing protein
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Small ribosomal subunit protein uS4 N-terminal
RNA 2-O ribose methyltransferase substrate binding
Cation-transporting P-type ATPase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Desulfoferrodoxin ferrous iron-binding domain-containing protein
Leucine-binding protein domain-containing protein
Outer membrane protein beta-barrel domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Involved in ionization of N3 of dUMP, leading to its activation
Magnesium transporter MgtE intracellular
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Cytochrome c7-like domain-containing protein
RNA binding; important for wobble base 34 recognition
Type II secretion system protein GspI C-terminal
Exonuclease VII large subunit C-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Ionotropic glutamate receptor C-terminal
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-96)
Interaction with polymerase core subunit RpoC
YbaK/aminoacyl-tRNA synthetase-associated
Translation elongation factor P/YeiP central
Cytochrome oxidase subunit II copper A binding
Alpha-amylase/4-alpha-glucanotransferase C-terminal
Alpha-amylase/4-alpha-glucanotransferase central
Glycoside hydrolase family 57 N-terminal
Formylmethanofuran dehydrogenase subunit E
DNA-directed DNA polymerase family A palm
Flagellar assembly protein FliH/Type III secretion system HrpE
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Nucleic acid binding OB-fold tRNA/helicase-type
Phosphoribosylformylglycinamidine synthase linker
Important for substrate specificity; cannot use PPi as phosphoryl donor
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Carboxypeptidase regulatory-like domain-containing protein
Chromosomal replication initiator DnaA C-terminal
Meso-diaminopimelate D-dehydrogenase C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Shikimate dehydrogenase substrate binding N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Electron transfer via tryptophanyl radical
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Transcription factor NikR nickel binding C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Sodium symporter small subunit predicted
1,4-alpha-glucan branching enzyme C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Proton acceptor; for glutaminase activity
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
NIF system FeS cluster assembly NifU C-terminal
NIF system FeS cluster assembly NifU N-terminal
Alginate export domain-containing protein
Sodium/calcium exchanger membrane region
Essential for prephenate dehydratase activity
Gamma-glutamylcyclotransferase AIG2-like
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Sugar fermentation stimulation protein C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Na+-translocating membrane potential-generating system MpsC
Could be important to modulate the pK values of the two catalytic cysteine residues
Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB C-terminal
Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB C-terminal domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
Membrane fusion protein biotin-lipoyl like
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Quercetin 2,3-dioxygenase C-terminal cupin
Type II secretion system protein GspC N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Cytochrome b/b6 N-terminal region profile