Gly-cisPro motif, important for rejection of L-amino acids
TonB-dependent receptor-like beta-barrel
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Quinohemoprotein amine dehydrogenase gamma subunit structural
AMP-activated protein kinase glycogen-binding
Glycosyl transferase family 3 N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
NIF system FeS cluster assembly NifU N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Putative regulatory protein FmdB Zinc ribbon
Saccharopine dehydrogenase-like C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Prepilin type IV endopeptidase peptidase
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
tRNA pseudouridylate synthase B C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
F420-non-reducing hydrogenase iron-sulfur subunit D
Alpha-glycerophosphate oxidase C-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Type I restriction enzyme R protein N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
Tryptophan synthase beta chain-like PALP
DNA helicase Holliday junction RuvA type
Acetylserotonin O-methyltransferase dimerisation
Important for substrate specificity; cannot use PPi as phosphoryl donor
Chemotaxis methyl-accepting receptor HlyB-like 4HB MCP
Major facilitator superfamily (MFS) profile
Conserved virulence factor B-like winged helix
Glycosyltransferase subfamily 4-like N-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
CO dehydrogenase/acetyl-CoA synthase delta subunit TIM barrel
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Polysaccharide biosynthesis protein CapD-like
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Ribose-phosphate pyrophosphokinase N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
L-seryl-tRNA selenium transferase N-terminal
Important for beta-aspartyl-AMP intermediate formation
Dinitrogenase iron-molybdenum cofactor biosynthesis
Polymerase/histidinol phosphatase N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Important for autoinhibition of adenylyltransferase activity
Pseudouridine synthase I TruA alpha/beta
Survival protein SurE-like phosphatase/nucleotidase
Thiamine pyrophosphate enzyme TPP-binding
RND efflux pump membrane fusion protein barrel-sandwich
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Reversibly protonated during proton transport
Large ribosomal subunit protein uL15/eL18
Transposase IS116/IS110/IS902 C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Pyridoxamine 5'-phosphate oxidase putative
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Penicillin-binding protein transpeptidase
Formylmethanofuran dehydrogenase subunit E
Phosphotransferase system enzyme I N-terminal
Methylene-tetrahydrofolate reductase C-terminal
6-hydroxymethylpterin diphosphokinase MptE-like
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Septum formation inhibitor MinC C-terminal
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Na+/H+ antiporter MnhB subunit-related protein
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Essential for prephenate dehydratase activity
Alanyl-transfer RNA synthetases family profile
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
PHA accumulation regulator DNA-binding N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Bacterial type II secretion system protein E
Pyruvate/ketoisovalerate oxidoreductase catalytic
O-(3'-phospho-DNA)-tyrosine intermediate
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Nitrite/Sulfite reductase ferredoxin-like
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Aminoacyl-tRNA synthetase class I anticodon-binding
Trigger factor ribosome-binding bacterial
FAD-dependent oxidoreductase 2 FAD binding
BREX system Lon protease-like BrxL N-terminal
ABC-type uncharacterised transport system
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
NADH-ubiquinone oxidoreductase 51kDa subunit FMN-binding
DNA mismatch repair proteins mutS family
Type III secretion system flagellar brake protein YcgR PilZN
Important for interaction with partner proteins
Cytochrome b561 bacterial/Ni-hydrogenase
Flagellar Assembly Protein A N-terminal region
CobB/CobQ-like glutamine amidotransferase
Flagellar motor switch protein FliN-like C-terminal
Type II secretion system protein GspC N-terminal
Thiamin pyrophosphokinase thiamin-binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
UDP N-acetylglucosamine O-acyltransferase C-terminal
Membrane iron-sulfur containing protein FtrD-like
Cysteine sulfenic acid (-SOH) intermediate
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Exonuclease VII large subunit C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
Involved in allosteric activation by GTP
Positions MEP for the nucleophilic attack
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
S-adenosyl-L-homocysteine hydrolase NAD binding
Sodium/calcium exchanger membrane region
Mannose-6-phosphate isomerase type II C-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
S-adenosylmethionine-dependent methyltransferase
Haem-binding uptake Tiki superfamily ChaN
Resolvase/invertase-type recombinase catalytic
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Release factor glutamine methyltransferase N-terminal
Polysaccharide chain length determinant N-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Anthranilate synthase component I N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
HicB-like antitoxin of toxin-antitoxin system
O-(5'-phospho-DNA)-tyrosine intermediate
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Type I restriction modification DNA specificity
Thymidylate synthase/dCMP hydroxymethylase
Probable endolytic peptidoglycan transglycosylase RlpA
Polysaccharide biosynthesis protein C-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Cytochrome C biogenesis protein transmembrane
DNA-directed DNA polymerase family A palm
Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding
Plays an important role in substrate specificity
Interaction with polymerase core subunit RpoC
Transposase IS204/IS1001/IS1096/IS1165 DDE
Heme-copper oxidase subunit III family profile
Membrane insertase YidC/Oxa/ALB C-terminal
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Carbon monoxide dehydrogenase subunit alpha ,N-terminal
DnaJ homologue subfamily C member 28 conserved
Putative Flp pilus-assembly TadG-like N-terminal
Damage-control phosphatase ARMT1-like metal-binding
Type II secretion system protein GspG C-terminal
Tellurite resistance methyltransferase TehB-like
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Translation elongation factor P/YeiP central
Arginine decarboxylase C-terminal helical
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Membrane fusion protein biotin-lipoyl like
NADH-rubredoxin oxidoreductase C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Ribosomal RNA small subunit methyltransferase E methyltransferase
Prokaryotic-type class I peptide chain release factors
Increases nucleophilicity of active site Cys
Putative auto-transporter adhesin head GIN
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Phosphoribosylformylglycinamidine synthase linker
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Small ribosomal subunit protein uS4 N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Large ribosomal subunit protein uL2 C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Solute-binding protein family 3/N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Siroheme decarboxylase AsnC-like ligand binding
Homocysteine biosynthesis enzyme sulfur-incorporation
RNA 2-O ribose methyltransferase substrate binding
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Large ribosomal subunit protein uL6 alpha-beta
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
DNA replication/recombination mediator RecO N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
RsbT co-antagonist protein RsbRD N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal