TonB-dependent receptor-like beta-barrel
Secretion system C-terminal sorting domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Could be important to modulate the pK values of the two catalytic cysteine residues
DNA mismatch repair proteins mutS family
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
O-(3'-phospho-DNA)-tyrosine intermediate
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Lipocalin-like domain-containing protein
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
RND efflux pump membrane fusion protein barrel-sandwich
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone oxidoreductase 30kDa subunit
NIF system FeS cluster assembly NifU C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Peptidase M10A and M12B matrixin and adamalysin
Homogentisate 1,2-dioxygenase N-terminal
Major facilitator superfamily (MFS) profile
Beta-hexosaminidase bacterial type N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Type I restriction modification DNA specificity
Schiff-base intermediate with substrate; via pyruvic acid
Release factor glutamine methyltransferase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
3-keto-disaccharide hydrolase domain-containing protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Sulfatase-modifying factor enzyme domain-containing protein
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Outer membrane lipoprotein-sorting protein
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Ribosomal RNA adenine methylase transferase N-terminal
Transition state stabilizer; via amide nitrogen
Pseudouridine synthase I TruA alpha/beta
Peptidase M1 membrane alanine aminopeptidase
Nuclear transport factor 2 family protein
Trigger factor ribosome-binding bacterial
Penicillin-binding protein transpeptidase
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Carboxypeptidase-like regulatory domain-containing protein
Aminoacyl-transfer RNA synthetases class-II family profile
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Limiting CO2-inducible protein B/C beta carbonyic anhydrase
TtsA-like Glycoside hydrolase family 108
TtsA-like Glycoside hydrolase family 108 domain-containing protein
Outer membrane protein beta-barrel domain-containing protein
Gylcosyl hydrolase 115 C-terminal domain-containing protein
RHS repeat-associated core domain-containing protein
Glycosyl transferase family 3 N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Nitrite/Sulfite reductase ferredoxin-like
Inosine/uridine-preferring nucleoside hydrolase domain-containing protein
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Membrane fusion protein biotin-lipoyl like
Small ribosomal subunit protein uS4 N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Organic solvent tolerance-like N-terminal
Glycine cleavage T-protein C-terminal barrel
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Tryptophan synthase beta chain-like PALP
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Mandelate racemase/muconate lactonizing enzyme C-terminal
ParB-related ThiF-related cassette protein E
Alpha-L-rhamnosidase six-hairpin glycosidase
Large ribosomal subunit protein uL2 C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Lysidine-tRNA(Ile) synthetase C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Glycosyl-hydrolase 97 C-terminal oligomerisation
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Saccharopine dehydrogenase-like C-terminal
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Type I restriction enzyme R protein N-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
UDP N-acetylglucosamine O-acyltransferase C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Peptidase S9 prolyl oligopeptidase catalytic
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Gly-cisPro motif, important for rejection of L-amino acids
Shikimate dehydrogenase substrate binding N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Polymerase/histidinol phosphatase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Signal transduction histidine kinase internal region
Ribose-phosphate pyrophosphokinase N-terminal
Prokaryotic glutathione synthetase ATP-binding
O-(5'-phospho-DNA)-tyrosine intermediate
4'-phosphopantetheinyl transferase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Inosine/uridine-preferring nucleoside hydrolase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Heme-copper oxidase subunit III family profile
ATP-grasp fold succinyl-CoA synthetase-type
Alpha-D-phosphohexomutase alpha/beta/alpha
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Bacterial transcription activator effector binding
Antitoxin Xre/MbcA/ParS-like toxin-binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Alginate lyase domain-containing protein
Glycoamylase-like domain-containing protein
ABC-type uncharacterised transport system
SUF system FeS cluster assembly SufBD N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
tRNA pseudouridylate synthase B C-terminal
Plays an important role in maintaining the position of the catalytic nucleophile
DNA replication/recombination mediator RecO N-terminal
Transcription regulator AsnC/Lrp ligand binding
Polysaccharide biosynthesis protein C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Aconitase A/isopropylmalate dehydratase small subunit swivel
Sialate O-acetylesterase domain-containing protein
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Phosphoribosylformylglycinamidine synthase linker
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
WD40-like beta Propeller containing protein
Butirosin biosynthesis protein H N-terminal
Reversibly protonated during proton transport
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Thymidylate synthase/dCMP hydroxymethylase
Bacterial alpha-L-rhamnosidase N-terminal
Thiamin pyrophosphokinase thiamin-binding
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Alpha-galactosidase NEW3 domain-containing protein
Alanyl-transfer RNA synthetases family profile
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Translation elongation factor EFTs/EF1B dimerisation
Ribonucleotide reductase large subunit C-terminal
Putative auto-transporter adhesin head GIN
Cation-transporting P-type ATPase C-terminal
Cation-transporting P-type ATPase N-terminal
Ribonucleotide reductase large subunit N-terminal
Polysaccharide chain length determinant N-terminal
Translation elongation factor P/YeiP central
Calcium-dependent phosphoinositide phospholipase C
Essential for prephenate dehydratase activity
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
General stress protein FMN-binding split barrel
N6 adenine-specific DNA methyltransferase N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
RNA binding; important for wobble base 34 recognition
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Proton acceptor; for glutaminase activity
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Cationic amino acid transporter C-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Na+/H+ antiporter MnhB subunit-related protein
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
N-end rule aminoacyl transferase C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Menaquinone biosynthesis protein MenD middle
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Auto-transporter adhesin head GIN domain-containing protein
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Alpha-glycerophosphate oxidase C-terminal
Large ribosomal subunit protein uL15/eL18
Neutral/alkaline non-lysosomal ceramidase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Anthranilate synthase component I N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Chromosomal replication initiator DnaA C-terminal
Glycoside hydrolase GH146 substrate-binding
Plays an important role in substrate specificity
Bacterial bifunctional deaminase-reductase C-terminal
Resolvase/invertase-type recombinase catalytic
Membrane protein involved in aromatic hydrocarbon degradation
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
DNA-directed DNA polymerase family A palm
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Peptidase C39-like domain-containing protein
Gliding motility-associated C-terminal domain-containing protein
Carbamoyl-phosphate synthase small subunit N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Haem-binding uptake Tiki superfamily ChaN
Haem-binding uptake Tiki superfamily ChaN domain-containing protein
Survival protein SurE-like phosphatase/nucleotidase
RNA 2-O ribose methyltransferase substrate binding
Glycoside hydrolase 123 C-terminal domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Putative beta-lactamase-inhibitor-like PepSY-like
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding