UDP-glucose/GDP-mannose dehydrogenase C-terminal
Na+/H+ antiporter MnhB subunit-related protein
Phosphatidic acid phosphatase type 2/haloperoxidase
Glycosyl transferase family 3 N-terminal
Type I restriction modification DNA specificity
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
SAM-dependent methyltransferase TRM5/TYW2-type
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Large ribosomal subunit protein uL15/eL18
Glycosyltransferase subfamily 4-like N-terminal
Glutamate synthase alpha subunit C-terminal
Transcription factor NikR nickel binding C-terminal
DNA-directed RNA polymerase subunit 2 hybrid-binding
Alanyl-transfer RNA synthetases family profile
Clathrin/coatomer adaptor adaptin-like N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Prepilin type IV endopeptidase peptidase
Pyridoxamine 5'-phosphate oxidase putative
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
Putative cytidyltransferase-related C-terminal region
Tryptophan synthase beta chain-like PALP
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Schiff-base intermediate with dihydroxyacetone-P
Alpha-D-phosphohexomutase alpha/beta/alpha
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Polysaccharide biosynthesis protein C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Aspartate/homoserine dehydrogenase NAD-binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Could be important to modulate the pK values of the two catalytic cysteine residues
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
60S ribosome subunit biogenesis protein NIP7 pre-PUA
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Mannose-6-phosphate isomerase type II C-terminal
tRNA nucleotidyltransferase substrate binding
Dinitrogenase iron-molybdenum cofactor biosynthesis
Carbamoyl-phosphate synthase small subunit N-terminal
Damage-control phosphatase ARMT1-like metal-binding
H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase C-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
F420-non-reducing hydrogenase iron-sulfur subunit D
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal
RNase L inhibitor RLI-like possible metal-binding
Pseudouridine synthase I TruA alpha/beta
Gamma-glutamylcyclotransferase AIG2-like
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
DNA polymerase alpha/delta/epsilon subunit B
Large ribosomal subunit protein uL6 alpha-beta
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Archaetidylserine decarboxylase alpha chain
Archaetidylserine decarboxylase beta chain
Cleavage (non-hydrolytic); by autocatalysis
Cation-transporting P-type ATPase N-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Small ribosomal subunit protein uS4 N-terminal
Transcription factor CBF/NF-Y/archaeal histone
Large ribosomal subunit protein uL2 C-terminal
Small ribosomal subunit protein eS4 N-terminal
Small ribosomal subunit protein eS4 central region
Methyl-coenzyme M reductase beta subunit C-terminal
Methyl-coenzyme M reductase beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
Major facilitator superfamily (MFS) profile
Methyl-coenzyme M reductase alpha subunit C-terminal
Methyl-coenzyme M reductase alpha subunit N-terminal
Solute-binding protein family 3/N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Pyruvate phosphate dikinase AMP/ATP-binding
Glycosyl transferase family 28 C-terminal
Removed in mature form; by autocatalysis
Spo11/DNA topoisomerase VI subunit A N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Hypoxanthine/guanine phosphoribosyltransferase
TATA box binding protein associated factor (TAF) histone-like fold
Polymerase/histidinol phosphatase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Schiff-base intermediate with D-ribose 5-phosphate
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Aconitase A/isopropylmalate dehydratase small subunit swivel
Formylmethanofuran dehydrogenase subunit E
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
Ribose-phosphate pyrophosphokinase N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Urease accessory protein UreH-like transmembrane
Small zinc finger protein HVO-2753-like zinc-binding pocket
Aminoacyl-tRNA synthetase class II (G/ P/ S/T)
6-hydroxymethylpterin diphosphokinase MptE-like
Anthranilate synthase component I N-terminal
Dihydroneopterin aldolase MtpD C-terminal
Thymidylate synthase/dCMP hydroxymethylase
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Probable transposase IS891/IS1136/IS1341
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
RNA polymerase subunit H/Rpb5 C-terminal
DNA-directed RNA polymerase RBP11-like dimerisation
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
N(4)-bis(aminopropyl)spermidine synthase C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Pyrimidine nucleoside phosphorylase C-terminal
Restriction endonuclease type II DpnII-like
May act as a substrate filter by repelling compounds with a negatively charged alpha-carboxylate
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Bacterial type II secretion system protein E
Phosphoribosylformylglycinamidine synthase linker
Important for beta-aspartyl-AMP intermediate formation
Tetrahydromethanopterin S-methyltransferase F subunit
Periplasmic copper-binding protein NosD beta helix
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Survival protein SurE-like phosphatase/nucleotidase
Peptidase A24A-predicted C-terminal archaea
Terminase large subunit gp17-like C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Translation elongation factor IF5A C-terminal