Glucosamine/galactosamine-6-phosphate isomerase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Sodium/calcium exchanger membrane region
Glycosyl transferase family 28 C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Interaction with polymerase core subunit RpoC
Type ISP restriction-modification enzyme LLaBIII C-terminal specificity
Large ribosomal subunit protein uL2 C-terminal
Superoxide dismutase copper/zinc binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Peptide methionine sulphoxide reductase MsrA
TRAP C4-dicarboxylate transport system permease DctM subunit
Shikimate dehydrogenase substrate binding N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
TonB-dependent receptor-like beta-barrel
Major facilitator superfamily (MFS) profile
Heat-inducible transcription repressor HrcA C-terminal
DNA topoisomerase I catalytic core eukaryotic-type
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Tryptophan synthase beta chain-like PALP
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Extensin-like C-terminal domain-containing protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-101)
Aminoacyl-transfer RNA synthetases class-II family profile
SGNH hydrolase-type esterase domain-containing protein
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Endoribonuclease L-PSP/chorismate mutase-like
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Terminase large subunit gp17-like C-terminal
Lysozyme inhibitor LprI N-terminal domain-containing protein
Important for beta-aspartyl-AMP intermediate formation
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Glycerophosphoryl diester phosphodiesterase membrane
Thiamine pyrophosphate enzyme TPP-binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
RNA 2-O ribose methyltransferase substrate binding
Glycine zipper domain-containing protein
Alanyl-transfer RNA synthetases family profile
ATP synthase F1 complex delta/epsilon subunit N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Methylene-tetrahydrofolate reductase C-terminal
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Transcriptional coactivator p15 (PC4) C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Penicillin-binding protein transpeptidase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aminoacyl-tRNA synthetase class I anticodon-binding
Helix-hairpin-helix DNA-binding motif class 1
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Pseudouridine synthase I TruA alpha/beta
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Glycosyltransferase subfamily 4-like N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Peptide methionine sulfoxide reductase MsrA
Polysaccharide biosynthesis protein C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Heavy-metal-associated domain-containing protein
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Glycosyltransferase family 28 N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Glycosyl transferase family 3 N-terminal
Glycosyl-hydrolase 97 C-terminal oligomerisation
O-(5'-phospho-DNA)-tyrosine intermediate
Membrane insertase YidC/Oxa/ALB C-terminal
Outer membrane protein assembly factor BamA
PHA accumulation regulator DNA-binding N-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Thioredoxin-like fold domain-containing protein
Survival protein SurE-like phosphatase/nucleotidase
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Phosphoribosylformylglycinamidine synthase linker
Deacetylase PdaC domain-containing protein
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Nitrite/Sulfite reductase ferredoxin-like
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Histidine phosphotransferase ChpT C-terminal
Cysteine sulfenic acid (-SOH) intermediate
RND efflux pump membrane fusion protein barrel-sandwich
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Tetrahydrodipicolinate-N-succinyltransferase chain A
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Carbamoyl-phosphate synthase small subunit N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Cobaltochelatase subunit CobS N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
S-adenosylmethionine-dependent methyltransferase
Glycine cleavage T-protein C-terminal barrel
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Beta-barrel assembly machine subunit BamF
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Thymidylate synthase/dCMP hydroxymethylase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Involved in allosteric activation by GTP
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
PhoD-like phosphatase metallophosphatase
Alpha-glycerophosphate oxidase C-terminal
Reversibly protonated during proton transport
Bacterial DNA polymerase III alpha subunit NTPase
DNA polymerase helix-hairpin-helix motif
Pili assembly chaperone N-terminal domain-containing protein
DNA-directed DNA polymerase family A palm
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
NADH:ubiquinone oxidoreductase 30kDa subunit
Alpha-D-phosphohexomutase alpha/beta/alpha
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Pyruvate phosphate dikinase AMP/ATP-binding
Schiff-base intermediate with substrate; via pyruvic acid
Plays an important role in substrate specificity
Release factor glutamine methyltransferase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Outer membrane lipoprotein-sorting protein
N-end rule aminoacyl transferase C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Signal transduction histidine kinase dimerisation/phosphoacceptor
Ribose-phosphate pyrophosphokinase N-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
SUF system FeS cluster assembly SufBD N-terminal
Cytochrome C biogenesis protein transmembrane
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Polymerase/histidinol phosphatase N-terminal
Small ribosomal subunit protein uS4 N-terminal
Outer membrane protein beta-barrel domain-containing protein
Important for interaction with partner proteins
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Heme-copper oxidase subunit III family profile
Polysaccharide chain length determinant N-terminal
Proton acceptor; for glutaminase activity
RNA 3'-terminal phosphate cyclase insert
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Ribosomal RNA adenine methylase transferase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Phosphatidate phosphatase APP1 catalytic
Cytochrome c-type biogenesis protein CcmF C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Protein O-mannosyl-transferase C-terminal four TM
Translation elongation factor P/YeiP central
General stress protein FMN-binding split barrel
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Methionyl-tRNA synthetase anticodon-binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Signal transduction histidine kinase HWE region
Organic solvent tolerance-like N-terminal
ABC-type transport auxiliary lipoprotein component
Prokaryotic-type class I peptide chain release factors
Putative Flp pilus-assembly TadG-like N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Chromosomal replication initiator DnaA C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Invasion associated locus B (IalB) protein
Prepilin type IV endopeptidase peptidase
Cytochrome b561 bacterial/Ni-hydrogenase
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
Histidine-specific methyltransferase SAM-dependent
DNA replication/recombination mediator RecO N-terminal
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
O-(3'-phospho-DNA)-tyrosine intermediate
Signal recognition particle SRP54 helical bundle