Helix-hairpin-helix DNA-binding motif class 1
Polymerase/histidinol phosphatase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Methylene-tetrahydrofolate reductase C-terminal
Anthranilate synthase component I N-terminal
Exonuclease VII large subunit C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
SAM-dependent methyltransferase TRM5/TYW2-type
Probable transposase IS891/IS1136/IS1341
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Cysteine sulfenic acid (-SOH) intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Interchain (with Cys-247); in linked form
Interchain (with Cys-59); in linked form
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
N6 adenine-specific DNA methyltransferase N-terminal
DNA-directed RNA polymerase RBP11-like dimerisation
Glucose-6-phosphate isomerase prokaryote
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Interchain (with Cys-223); in linked form
Interchain (with Cys-55); in linked form
Large ribosomal subunit protein uL15/eL18
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Damage-control phosphatase ARMT1-like metal-binding
Cytochrome C biogenesis protein transmembrane
Schiff-base intermediate with dihydroxyacetone-P
Major facilitator superfamily (MFS) profile
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Carbamoyl-phosphate synthase small subunit N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
DNA polymerase alpha/delta/epsilon subunit B
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Small ribosomal subunit protein uS4 N-terminal
Pseudouridine synthase I TruA alpha/beta
Translation elongation factor IF5A C-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Resolvase/invertase-type recombinase catalytic
NADH:flavin oxidoreductase/NADH oxidase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Archaeal glycosylation protein B peripheral
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
ABC-type glycine betaine transport system substrate-binding
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Bacteriophage/plasmid primase P4 C-terminal
Polysaccharide biosynthesis protein C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Na+/H+ antiporter MnhB subunit-related protein
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pyruvate phosphate dikinase AMP/ATP-binding
Survival protein SurE-like phosphatase/nucleotidase
S-adenosyl-L-homocysteine hydrolase NAD binding
Hypoxanthine/guanine phosphoribosyltransferase
Methanogenesis regulatory protein FilR1 middle
Cytochrome c-type biogenesis protein CcmF C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Glycogen debranching enzyme bacterial and archaeal type N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Small ribosomal subunit protein uS15 N-terminal
Small zinc finger protein HVO-2753-like zinc-binding pocket
Nitrite/Sulfite reductase ferredoxin-like
Tryptophan synthase beta chain-like PALP
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal
RNase L inhibitor RLI-like possible metal-binding
Glycoside hydrolase family 57 N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Aspartate/homoserine dehydrogenase NAD-binding
Phosphoribosylformylglycinamidine synthase linker
RNA polymerase subunit H/Rpb5 C-terminal
tRNA nucleotidyltransferase substrate binding
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Could be important to modulate the pK values of the two catalytic cysteine residues
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Alanyl-transfer RNA synthetases family profile
DNA mismatch repair proteins mutS family
Thiamine pyrophosphate enzyme TPP-binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Formylmethanofuran dehydrogenase subunit E
Thymidylate synthase/dCMP hydroxymethylase
Sodium/calcium exchanger membrane region
Alpha-D-phosphohexomutase alpha/beta/alpha
FAD-dependent oxidoreductase 2 FAD binding
Transcription factor NikR nickel binding C-terminal
Type I restriction modification DNA specificity
Phosphoadenosine phosphosulphate reductase
Pyrimidine nucleoside phosphorylase C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
RNA 3'-terminal phosphate cyclase insert
Pyruvoyl-dependent arginine decarboxylase subunit alpha
Pyruvoyl-dependent arginine decarboxylase subunit beta
DNA-directed RNA polymerase subunit 2 hybrid-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Bacterial type II secretion system protein E
Gamma-glutamylcyclotransferase AIG2-like
Periplasmic copper-binding protein NosD beta helix
Large ribosomal subunit protein uL6 alpha-beta
Tetrahydromethanopterin S-methyltransferase F subunit
Plays an important role in substrate specificity
CO dehydrogenase/acetyl-CoA synthase delta subunit TIM barrel
Tetrahydromethanopterin S-methyltransferase subunit A
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Glycosyltransferase subfamily 4-like N-terminal
Type I restriction enzyme R protein N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Signal recognition particle SRP54 helical bundle
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
DNA polymerase II large subunit DP2 N-terminal
Large ribosomal subunit protein uL2 C-terminal
Transcription factor CBF/NF-Y/archaeal histone
Glycosyl transferase family 3 N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Mannose-6-phosphate isomerase type II C-terminal
Siroheme decarboxylase AsnC-like ligand binding
Glutamate synthase alpha subunit C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Glycosyl transferase family 28 C-terminal
Removed in mature form; by autocatalysis
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Methyl-coenzyme M reductase alpha subunit C-terminal
Methyl-coenzyme M reductase alpha subunit N-terminal
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Gram-positive cocci surface proteins LPxTG
Dinitrogenase iron-molybdenum cofactor biosynthesis
Electron transfer via tryptophanyl radical
Cation-transporting P-type ATPase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Actinobacteria/chloroflexi VLRF1 release factor
DNA topoisomerase VI subunit B C-terminal
DNA topoisomerase VI subunit B transducer
Methyl-coenzyme M reductase beta subunit C-terminal
Methyl-coenzyme M reductase beta subunit N-terminal
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Dihydroneopterin aldolase MtpD C-terminal
Prepilin type IV endopeptidase peptidase
Peptide methionine sulphoxide reductase MsrA
Spo11/DNA topoisomerase VI subunit A N-terminal