Thiopeptide-type bacteriocin biosynthesis
Pyridoxamine 5'-phosphate oxidase putative
Endoribonuclease L-PSP/chorismate mutase-like
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Rv2525c-like glycoside hydrolase-like domain-containing protein
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Transcription regulator AsnC/Lrp ligand binding
Major facilitator superfamily (MFS) profile
YbaK/aminoacyl-tRNA synthetase-associated
Tryptophan synthase beta chain-like PALP
Glycoside hydrolase family 42 N-terminal
Peptidoglycan recognition protein family
Saccharopine dehydrogenase-like C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
PhoD-like phosphatase metallophosphatase
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Flagellar hook-length control protein FliK
Cytochrome oxidase subunit II copper A binding
Cell envelope-related transcriptional attenuator
Phosphatidic acid phosphatase type 2/haloperoxidase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Membrane insertase YidC/Oxa/ALB C-terminal
Conserved hypothetical protein CHP02679 N terminus
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Glycosyl hydrolase-like 10 domain-containing protein
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Erythromycin biosynthesis protein CIII-like central
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Peptidase S9 prolyl oligopeptidase catalytic
Activator of Hsp90 ATPase homologue 1-like C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Cytochrome b/b6 N-terminal region profile
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Glutathionylspermidine synthase pre-ATP-grasp-like
Alpha-D-phosphohexomutase alpha/beta/alpha
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cysteine sulfenic acid (-SOH) intermediate
Bacterial bifunctional deaminase-reductase C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Septum formation-related domain-containing protein
Prokaryotic-type class I peptide chain release factors
Glycoside hydrolase family 31 N-terminal
Putative regulatory protein FmdB Zinc ribbon
Polysaccharide biosynthesis protein C-terminal
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Transposase IS116/IS110/IS902 C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
DNA-directed DNA polymerase family A palm
4'-phosphopantetheinyl transferase N-terminal
Penicillin-binding protein transpeptidase
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
NADH-rubredoxin oxidoreductase C-terminal
Peptidase M43 pregnancy-associated plasma-A
Peptidase M43 pregnancy-associated plasma-A domain-containing protein
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
RNA 2-O ribose methyltransferase substrate binding
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Peptidase C39-like domain-containing protein
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Cation-transporting P-type ATPase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
MinD-like ATPase involved in chromosome partitioning or flagellar assembly
Alpha-L-arabinofuranosidase B arabinose-binding
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Glucose/Sorbosone dehydrogenase domain-containing protein
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Gly-cisPro motif, important for rejection of L-amino acids
NIF system FeS cluster assembly NifU C-terminal
Putative Flp pilus-assembly TadG-like N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Large ribosomal subunit protein uL2 C-terminal
Small ribosomal subunit protein uS4 N-terminal
Prepilin type IV endopeptidase peptidase
Histidine-specific methyltransferase SAM-dependent
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Membrane fusion protein biotin-lipoyl like
L-seryl-tRNA selenium transferase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Beta-hexosaminidase bacterial type N-terminal
CobB/CobQ-like glutamine amidotransferase
Butirosin biosynthesis protein H N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Gram-positive cocci surface proteins LPxTG
Large ribosomal subunit protein uL6 alpha-beta
Probable inorganic carbon transporter subunit DabA
Peptidase M1 membrane alanine aminopeptidase
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Acyltransferase MbtK/IucB-like conserved
ABC-type glycine betaine transport system substrate-binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Positions MEP for the nucleophilic attack
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Ricin B lectin domain-containing protein
Polymerase/histidinol phosphatase N-terminal
Involved in ionization of N3 of dUMP, leading to its activation
SUF system FeS cluster assembly SufBD N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Solute-binding protein family 3/N-terminal
von Hippel-Lindau disease tumour suppressor beta
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Mannose-6-phosphate isomerase type II C-terminal
Choloylglycine hydrolase/NAAA C-terminal
LPXTG cell wall anchor domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
NADH-ubiquinone oxidoreductase 51kDa subunit FMN-binding
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Glucosamine/galactosamine-6-phosphate isomerase
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
N-terminal domain of peptidoglycan hydrolase CwlO-containing protein
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Periplasmic binding protein domain-containing protein
S-adenosyl-L-homocysteine hydrolase NAD binding
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Heme-copper oxidase subunit III family profile
Nitrite/Sulfite reductase ferredoxin-like
Cytochrome C biogenesis protein transmembrane
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Contractile injection system tube protein N-terminal
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
glutathione gamma-glutamylcysteinyltransferase
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Phosphomannose isomerase type I catalytic
Could be important to modulate the pK values of the two catalytic cysteine residues
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Signal recognition particle SRP54 helical bundle
Chromosomal replication initiator DnaA C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
TRAP C4-dicarboxylate transport system permease DctM subunit
Proton acceptor; for glutaminase activity
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Diacylglycerol glucosyltransferase N-terminal
Large ribosomal subunit protein uL15/eL18
Pyruvate phosphate dikinase AMP/ATP-binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Bacterial type II secretion system protein E
Protein O-mannosyl-transferase C-terminal four TM
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Acyl-CoA dehydrogenase C-terminal bacterial-type
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
DNA replication/recombination mediator RecO N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Polysaccharide chain length determinant N-terminal
AMP-activated protein kinase glycogen-binding
Putative glycogen debranching enzyme N-terminal
Phosphoribosylformylglycinamidine synthase linker
NADH:ubiquinone oxidoreductase 30kDa subunit
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Pectate lyase superfamily protein domain-containing protein
Sodium/calcium exchanger membrane region
DNA topoisomerase I catalytic core eukaryotic-type
Sporulation transcription regulator WhiA N-terminal
Glycogen debranching enzyme bacterial and archaeal type N-terminal
6-phosphogluconate dehydrogenase NADP-binding
6-phosphogluconate dehydrogenase C-terminal
Schiff-base intermediate with D-ribose 5-phosphate
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
SGNH hydrolase-type esterase domain-containing protein
Important for beta-aspartyl-AMP intermediate formation
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Plays an important role in substrate specificity
Cell wall-active antibiotics response LiaF-like C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Glycosyl transferase family 3 N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Survival protein SurE-like phosphatase/nucleotidase
Adaptive response protein AidB N-terminal
Trigger factor ribosome-binding bacterial
Glycoside-hydrolase family GH114 TIM-barrel
DnaJ homologue subfamily C member 28 conserved
N,N-dimethylformamidase beta subunit-like C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pseudouridine synthase I TruA alpha/beta
Shikimate dehydrogenase substrate binding N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
General stress protein FMN-binding split barrel
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Probable endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Carboxypeptidase regulatory-like domain-containing protein
Gp5/Type VI secretion system Vgr protein OB-fold
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Methionyl-tRNA synthetase anticodon-binding
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Tat pathway signal sequence domain protein
Quinolinate phosphoribosyl transferase N-terminal
Essential for prephenate dehydratase activity
Alanyl-transfer RNA synthetases family profile
Moybdenum cofactor oxidoreductase dimerisation
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Translation elongation factor P/YeiP central
GDSL-like Lipase/Acylhydrolase family protein
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Helix-hairpin-helix DNA-binding motif class 1
non-reducing end alpha-L-arabinofuranosidase
Schiff-base intermediate with substrate; via pyruvic acid
Reversibly protonated during proton transport
Peptide methionine sulphoxide reductase MsrA
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-128)
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
PknH-like extracellular domain-containing protein
NIF system FeS cluster assembly NifU N-terminal
Endonuclease/exonuclease/phosphatase family protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Electron transfer via tryptophanyl radical
Anthranilate synthase component I N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Ribosomal RNA adenine methylase transferase N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Polysaccharide biosynthesis protein CapD-like
Pyrroline-5-carboxylate reductase dimerisation
DNA primase/polymerase bifunctional N-terminal