Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Flagellar motor switch protein FliN-like C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
RNA polymerase sigma factor 70 region 4 type 2
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Putative regulatory protein FmdB Zinc ribbon
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Interaction with polymerase core subunit RpoC
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Translation elongation factor P/YeiP central
NIF system FeS cluster assembly NifU N-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Tryptophan synthase beta chain-like PALP
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Cation-transporting P-type ATPase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Aminoacyl-transfer RNA synthetases class-II family profile
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
TonB-dependent receptor-like beta-barrel
DNA-3-methyladenine glycosylase AlkA N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
P-type conjugative transfer protein TrbJ
Pseudouridine synthase I TruA alpha/beta
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Prepilin type IV endopeptidase peptidase
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Survival protein SurE-like phosphatase/nucleotidase
Acyl-CoA dehydrogenase C-terminal bacterial-type
Cysteine sulfenic acid (-SOH) intermediate
Phosphatidic acid phosphatase type 2/haloperoxidase
EfeO-type cupredoxin-like domain-containing protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
O-(5'-phospho-DNA)-tyrosine intermediate
Phosphoadenosine phosphosulphate reductase
Heme-copper oxidase subunit III family profile
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
non-specific serine/threonine protein kinase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Glycine zipper 2TM domain-containing protein
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Membrane insertase YidC/Oxa/ALB C-terminal
RNA binding; important for wobble base 34 recognition
Ribose-phosphate pyrophosphokinase N-terminal
Exonuclease VII large subunit C-terminal
ABC-type transport auxiliary lipoprotein component
NarX-like N-terminal domain-containing protein
Prokaryotic-type class I peptide chain release factors
CobB/CobQ-like glutamine amidotransferase
Type III secretion system flagellar brake protein YcgR PilZN
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Flagellar basal body rod protein N-terminal
Plays an important role in substrate specificity
Pyruvate phosphate dikinase AMP/ATP-binding
Major facilitator superfamily (MFS) profile
Polymerase/histidinol phosphatase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Flavocytochrome c sulphide dehydrogenase flavin-binding
Positions MEP for the nucleophilic attack
Potassium-transporting ATPase KdpC subunit
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Solute-binding protein family 3/N-terminal
Flagellar hook-length control protein-like C-terminal
Periplasmic nitrate reductase, electron transfer subunit
Thioredoxin-like fold domain-containing protein
Transglutaminase-like domain-containing protein
Required for dimer formation and molybdate binding
Type IV pilus biogenesis and competence protein PilQ
Proton acceptor; for glutaminase activity
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Cytochrome b561 bacterial/Ni-hydrogenase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Transposase IS116/IS110/IS902 C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Heat-inducible transcription repressor HrcA C-terminal
Chromosomal replication initiator DnaA C-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Replication-associated protein G2P N-terminal
Small ribosomal subunit protein uS4 N-terminal
Flagellar basal-body/hook protein C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Polysaccharide biosynthesis protein CapD-like
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Release factor glutamine methyltransferase N-terminal
Membrane fusion protein biotin-lipoyl like
DNA-directed DNA polymerase family A palm
Ribosomal RNA adenine methylase transferase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Important for interaction with partner proteins
Alpha-D-phosphohexomutase alpha/beta/alpha
ATP synthase F1 complex delta/epsilon subunit N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
S-adenosylmethionine-dependent methyltransferase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Electron transfer via tryptophanyl radical
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-100)
Gly-cisPro motif, important for rejection of L-amino acids
Glycosyltransferase subfamily 4-like N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
TRAP C4-dicarboxylate transport system permease DctM subunit
Bacterial type II secretion system protein E
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Penicillin-binding protein transpeptidase
Gp5/Type VI secretion system Vgr protein OB-fold
Putative type VI secretion system Rhs element associated Vgr
Terminase large subunit gp17-like C-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Anthranilate synthase component I N-terminal
Transcription elongation factor GreA/GreB C-terminal
Alanyl-transfer RNA synthetases family profile
Nucleophile; cysteine thiosulfonate intermediate
Four-helix bundle copper-binding protein
Tetrahydrodipicolinate-N-succinyltransferase chain A
Type II restriction enzyme and methyltransferase RM.Eco57I-like
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Essential for prephenate dehydratase activity
Molybdopterin cofactor biosynthesis C (MoaC)
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Glycosyl transferase family 3 N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Transcription elongation factor GreA/GreB N-terminal
Glycine cleavage T-protein C-terminal barrel
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Gamma-butyrobetaine hydroxylase-like N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Cob(I)alamin adenosyltransferase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
DNA mismatch repair proteins mutS family
Transcription factor NikR nickel binding C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Phosphoethanolamine transferase N-terminal
Large ribosomal subunit protein uL2 C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Nitrogenase molybdenum-iron protein beta chain N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Outer membrane protein assembly factor BamA
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Required for zinc-mediated homotetramerization and catalytic activity
Helix-hairpin-helix DNA-binding motif class 1
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Lipoprotein SmpA/OmlA domain-containing protein
Resolvase/invertase-type recombinase catalytic
PHA accumulation regulator DNA-binding N-terminal
Virulence factor membrane-bound polymerase C-terminal
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Protein-methionine-sulfoxide reductase catalytic subunit MsrP
Flagella basal body P-ring formation protein FlgA
Mandelate racemase/muconate lactonizing enzyme C-terminal
Siroheme decarboxylase AsnC-like ligand binding
Putative protein-methionine-sulfoxide reductase subunit YedZ1
DNA polymerase III subunit delta C-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Endolytic peptidoglycan transglycosylase RlpA
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Pyruvate dehydrogenase E1 component middle
Could be important to modulate the pK values of the two catalytic cysteine residues
NADH:ubiquinone oxidoreductase 30kDa subunit
Reversibly protonated during proton transport
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Outer membrane protein assembly factor BamD
Tle cognate immunity protein 4 C-terminal
Tle cognate immunity protein 4 N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Cytochrome c-552/DMSO reductase-like haem-binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Type 2A encapsulin shell protein SrpI-like
Periplasmic copper-binding protein NosD beta helix
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
S-adenosyl-L-homocysteine hydrolase NAD binding
Inner membrane protein YgaP-like transmembrane
Quercetin 2,3-dioxygenase C-terminal cupin
5-glutamyl coenzyme A thioester intermediate
Ribonucleotide reductase large subunit C-terminal
Curli production assembly/transport component CsgG
Phosphate ABC transporter substrate-binding protein
Interacts with tRNA; defines subfamily-specific binding signature
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Flagellar assembly protein FliH/Type III secretion system HrpE
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
N-end rule aminoacyl transferase C-terminal
Flagellar Assembly Protein A N-terminal region
Aminoacyl-tRNA synthetase class I anticodon-binding
DNA replication/recombination mediator RecO N-terminal
Sugar fermentation stimulation protein C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Large ribosomal subunit protein uL15/eL18
NAD(P) transhydrogenase alpha subunit C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Lytic transglycosylase superhelical linker
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Sodium symporter small subunit predicted
Outer membrane protein assembly factor BamB
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Major facilitator superfamily associated
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Phosphotransferase system enzyme I N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal