Haem-binding uptake Tiki superfamily ChaN
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Cysteine sulfenic acid (-SOH) intermediate
Schiff-base intermediate with dihydroxyacetone-P
Major facilitator superfamily (MFS) profile
Glucosamine/galactosamine-6-phosphate isomerase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
L-cysteine S-thiosulfotransferase subunit SoxA
Septum formation inhibitor MinC C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Interaction with polymerase core subunit RpoC
Thiamine pyrophosphate enzyme TPP-binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Probable transposase IS891/IS1136/IS1341
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Tryptophan synthase beta chain-like PALP
DNA-directed DNA polymerase family A palm
ATP-grasp fold succinyl-CoA synthetase-type
Proton acceptor; for glutaminase activity
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Bacterial bifunctional deaminase-reductase C-terminal
Sugar fermentation stimulation protein C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Large ribosomal subunit protein uL6 alpha-beta
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
NADH:ubiquinone oxidoreductase 30kDa subunit
DNA mismatch repair proteins mutS family
Alpha-D-phosphohexomutase alpha/beta/alpha
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Translation elongation factor P/YeiP central
6-phosphogluconate dehydrogenase C-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Magnesium transporter MgtE intracellular
Superoxide dismutase copper/zinc binding
Polymerase/histidinol phosphatase N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Membrane fusion protein biotin-lipoyl like
Polysaccharide biosynthesis protein C-terminal
Mannose-6-phosphate isomerase type II C-terminal
Cytochrome C biogenesis protein transmembrane
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Ribose-phosphate pyrophosphokinase N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Cation-transporting P-type ATPase N-terminal
Bacterial type II secretion system protein E
tRNA (guanine-N(1)-)-methyltransferase C-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
RlpA-like protein double-psi beta-barrel
Type II restriction enzyme and methyltransferase RM.Eco57I-like
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Quinohemoprotein amine dehydrogenase alpha subunit haem binding
Quinohemoprotein amine dehydrogenase alpha subunit haem binding domain-containing protein
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
RNA binding; important for wobble base 34 recognition
Aspartate/homoserine dehydrogenase NAD-binding
Glycine cleavage T-protein C-terminal barrel
Chromosomal replication initiator DnaA C-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Small ribosomal subunit protein uS4 N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Flagella basal body P-ring formation protein FlgA C-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
N(4)-bis(aminopropyl)spermidine synthase C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Inner membrane protein YgaP-like transmembrane
Type II secretion system protein GspG C-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Important for interaction with partner proteins
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Important for guanine/8-oxoguanine distinction
Release factor glutamine methyltransferase N-terminal
Flagellar motor switch protein FliN-like C-terminal
NIF system FeS cluster assembly NifU N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Molybdopterin cofactor biosynthesis C (MoaC)
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
NIF system FeS cluster assembly NifU C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Polysaccharide chain length determinant N-terminal
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
UDP N-acetylglucosamine O-acyltransferase C-terminal
Helix-hairpin-helix DNA-binding motif class 1
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Large ribosomal subunit protein uL2 C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Flavocytochrome c sulphide dehydrogenase flavin-binding
RND efflux pump membrane fusion protein barrel-sandwich
Sigma 54 modulation/S30EA ribosomal protein C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Positions MEP for the nucleophilic attack
Prokaryotic-type class I peptide chain release factors
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Phosphoribosylformylglycinamidine synthase linker
Alanyl-transfer RNA synthetases family profile
Shikimate dehydrogenase substrate binding N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
SMODS-associated and fused to various effectors
TonB-dependent receptor-like beta-barrel
Pyridoxamine 5'-phosphate oxidase putative
Large ribosomal subunit protein uL15/eL18
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Involved in allosteric activation by GTP
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Penicillin-binding protein transpeptidase
Heme-copper oxidase subunit III family profile
Plays an important role in substrate specificity
Pseudouridine synthase I TruA alpha/beta
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Dihydroorotate dehydrogenase electron transfer subunit iron-sulphur cluster binding
Transcription factor NikR nickel binding C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Glycosyl transferase family 3 N-terminal
Moybdenum cofactor oxidoreductase dimerisation
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Survival protein SurE-like phosphatase/nucleotidase
Methionyl-tRNA synthetase anticodon-binding
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Could be important to modulate the pK values of the two catalytic cysteine residues
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Glycoside hydrolase family 57 N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Essential for prephenate dehydratase activity
DNA-directed RNA polymerase RpoA/D/Rpb3-type
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Anthranilate synthase component I N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal