NIF system FeS cluster assembly NifU C-terminal
Important for beta-aspartyl-AMP intermediate formation
ABC-type sugar transport system, ATPase component
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
TonB-dependent receptor-like beta-barrel
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
UDP-glucose/GDP-mannose dehydrogenase C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Divergent polysaccharide deacetylase family protein
Conserved virulence factor B-like winged helix
Trimeric autotransporter adhesin YadA-like C-terminal membrane anchor
Trimeric autotransporter adhesin YadA-like C-terminal membrane anchor domain-containing protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Pili assembly chaperone N-terminal domain-containing protein
Major facilitator superfamily (MFS) profile
UDP-3-O-acyl-N-acetylglucosamine deacetylase
RNA methyltransferase SpoU/TrmH type C-terminal
Survival protein SurE-like phosphatase/nucleotidase
Phosphatidic acid phosphatase type 2/haloperoxidase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
TonB system biopolymer transport component
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Tryptophan synthase beta chain-like PALP
Pyridine nucleotide-disulphide oxidoreductase dimerisation
DNA-directed RNA polymerase subunit alpha
Tetrahydrodipicolinate-N-succinyltransferase chain A
Biopterin-dependent aromatic amino acid hydroxylase family profile
Ribose-phosphate pyrophosphokinase N-terminal
Solute-binding protein family 3/N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Required for zinc-mediated homotetramerization and catalytic activity
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
YbaK/aminoacyl-tRNA synthetase-associated
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Cytochrome c-type biogenesis protein CcmF C-terminal
Chromosomal replication initiator protein DnaA
Acyl-CoA dehydrogenase C-terminal bacterial-type
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
DNA mismatch repair proteins mutS family
Thiol:disulfide interchange protein DsbD N-terminal
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Interaction with polymerase core subunit RpoC
Heme-copper oxidase subunit III family profile
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Mechanosensitive ion channel inner membrane
NADH:ubiquinone oxidoreductase 30kDa subunit
TRAP C4-dicarboxylate transport system permease DctM subunit
Type 4 fimbrial biogenesis protein PilX N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Peptidase S9 prolyl oligopeptidase catalytic
Methyltransferase type 11 domain-containing protein
Sodium/calcium exchanger membrane region
Involved in allosteric activation by GTP
Bacterial surface antigen (D15) domain-containing protein
Membrane fusion protein biotin-lipoyl like
Pyrimidine nucleoside phosphorylase C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Bacterial type II secretion system protein E
Polymerase/histidinol phosphatase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Transition state stabilizer; via amide nitrogen
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Chromosomal replication initiator DnaA C-terminal
Choloylglycine hydrolase/NAAA C-terminal
Ribosomal RNA small subunit methyltransferase H
Putative Flp pilus-assembly TadG-like N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
Prokaryotic-type class I peptide chain release factors
Large ribosomal subunit protein bL25 L25
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Fibronectin type-III domain-containing protein
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
DNA-directed RNA polymerase subunit omega
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Subtilisin-like protease fibronectin type-III
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Flagella basal body P-ring formation protein FlgA
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Interacts with tRNA; defines subfamily-specific binding signature
Could play a key role in the communication between the regulatory and the substrate sites
Penicillin-binding protein transpeptidase
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Solute-binding protein family 3/N-terminal domain-containing protein
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Cytochrome b561 bacterial/Ni-hydrogenase
Sodium symporter small subunit predicted
Phosphoadenosine phosphosulphate reductase
RNA 2-O ribose methyltransferase substrate binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
DNA-directed DNA polymerase family A palm
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Polysaccharide chain length determinant N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Reversibly protonated during proton transport
Translation elongation factor P/YeiP central
Flagellar assembly protein FliH/Type III secretion system HrpE
RNA polymerase sigma factor 70 region 4 type 2
Outer membrane protein beta-barrel domain-containing protein
Phosphotransferase system enzyme I N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Formate-dependent nitrite reductase complex subunit
Small ribosomal subunit protein uS4 N-terminal
Intracellular proteinase inhibitor BsuPI
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
RNA binding; important for wobble base 34 recognition
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Plays an important role in substrate specificity
Schiff-base intermediate with acetaldehyde
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Peptidase C-terminal archaeal/bacterial domain-containing protein
Inosine/uridine-preferring nucleoside hydrolase
Glucosamine/galactosamine-6-phosphate isomerase
Flagellar motor switch protein FliN-like C-terminal
Positions MEP for the nucleophilic attack
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Peptidase M43 pregnancy-associated plasma-A
ABC-type glycine betaine transport system substrate-binding
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Urease accessory protein UreH-like transmembrane
Outer membrane protein OmpA-like transmembrane
Flagellar Assembly Protein A N-terminal region
Glycosyltransferase subfamily 4-like N-terminal
Peptidase M1 membrane alanine aminopeptidase
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
ATP synthase F1 complex delta/epsilon subunit N-terminal
Negative modulator of initiation of replication SeqA N-terminal
Replication modulator SeqA C-terminal DNA-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Alginate export domain-containing protein
ABC-type transport auxiliary lipoprotein component
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Important for interaction with partner proteins
Glycosyl transferase family 3 N-terminal
Curli production assembly/transport component CsgG
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Important for autoinhibition of adenylyltransferase activity
Plays an important role in discriminating NADH against NADPH
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Auto-transporter adhesin head GIN domain-containing protein
Chalcone isomerase domain-containing protein
Large ribosomal subunit protein uL2 C-terminal
NIF system FeS cluster assembly NifU N-terminal
Periplasmic nitrate reductase, electron transfer subunit
UDP N-acetylglucosamine O-acyltransferase C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Prepilin type IV endopeptidase peptidase
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Small-conductance mechanosensitive channel
glutathione gamma-glutamylcysteinyltransferase
Putative beta-barrel assembly-enhancing protease
Important for substrate binding and specificity
Appears to be important in orienting the phosphate for catalysis
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Signal transduction histidine kinase internal region
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
6-phosphogluconate dehydrogenase C-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Type II secretion system protein GspC N-terminal
Putative adhesin domain-containing protein
Gamma-butyrobetaine hydroxylase-like N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Large ribosomal subunit protein uL15/eL18
Heavy metal binding domain-containing protein
Lysidine-tRNA(Ile) synthetase C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Pyruvate phosphate dikinase AMP/ATP-binding
Ribosomal RNA adenine methylase transferase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
N-end rule aminoacyl transferase C-terminal
Yop protein translocation protein D periplasmic
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Release factor glutamine methyltransferase N-terminal
Outer membrane protein assembly factor BamB
DNA replication/recombination mediator RecO N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Peptidase M14 carboxypeptidase A domain-containing protein
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Outer membrane protein assembly factor BamA
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Outer-membrane lipoprotein carrier protein
Type II secretion system protein GspG C-terminal
Shikimate dehydrogenase substrate binding N-terminal
Peptide methionine sulphoxide reductase MsrA
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Ysc84 actin-binding domain-containing protein
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
Alanyl-transfer RNA synthetases family profile
Bacterial virulence factor lipase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Saccharopine dehydrogenase-like C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Glycosyl hydrolase family 63 C-terminal domain-containing protein
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Gly-cisPro motif, important for rejection of L-amino acids
UDP-N-acetylmuramoylalanine--D-glutamate ligase
For 3-hydroxyacyl-CoA dehydrogenase activity
Glycine cleavage T-protein C-terminal barrel
Integrin alpha beta-propellor repeat protein
Chaperone for general secretion pathway YbaY
Helix-hairpin-helix DNA-binding motif class 1
Hypersensitivity response secretion-like HrpJ
Threonine/serine exporter-like N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Tail specific protease domain-containing protein
Outer membrane lipoprotein carrier protein LolA
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Mannose-6-phosphate isomerase type II C-terminal
Thiol:disulfide interchange protein DsbD
Aldehyde oxidase/xanthine dehydrogenase first molybdopterin binding
Aldehyde oxidase/xanthine dehydrogenase second molybdopterin binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Menaquinone biosynthesis protein MenD middle
3-deoxy-D-manno-octulosonic-acid transferase N-terminal