Positions MEP for the nucleophilic attack
DNA replication/recombination mediator RecO N-terminal
Cation-transporting P-type ATPase N-terminal
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Major facilitator superfamily (MFS) profile
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
ABC transporter substrate-binding protein
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
HicB-like antitoxin of toxin-antitoxin system
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Large ribosomal subunit protein uL2 C-terminal
Glycosyltransferase subfamily 4-like N-terminal
DNA polymerase III delta subunit C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Phosphoadenosine phosphosulphate reductase
Penicillin-binding protein activator LpoA
Alpha-D-phosphohexomutase alpha/beta/alpha
Chalcone isomerase domain-containing protein
Membrane insertase YidC/Oxa/ALB C-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Heme-copper oxidase subunit III family profile
Bacterial type II secretion system protein E
Pyruvate phosphate dikinase AMP/ATP-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Important for interaction with partner proteins
Glycine zipper domain-containing protein
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Tryptophan synthase beta chain-like PALP
Aminoacyl-transfer RNA synthetases class-II family profile
Reversibly protonated during proton transport
UDP N-acetylglucosamine O-acyltransferase C-terminal
Prepilin type IV endopeptidase peptidase
Gamma-butyrobetaine hydroxylase-like N-terminal
High potential iron-sulfur proteins family profile
High potential iron-sulfur proteins family profile domain-containing protein
ATP synthase F1 complex delta/epsilon subunit N-terminal
Plays an important role in substrate specificity
O-(5'-phospho-DNA)-tyrosine intermediate
Phosphate starvation-inducible protein PsiF
RNA polymerase sigma factor 70 region 4 type 2
CagE TrbE VirB component of type IV transporter system central
Cytochrome oxidase subunit II copper A binding
Probable transposase IS891/IS1136/IS1341
TonB-dependent receptor-like beta-barrel
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Toxin co-regulated pilus biosynthesis protein Q C-terminal domain-containing protein
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
N6 adenine-specific DNA methyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
DNA mismatch repair proteins mutS family
Peptide methionine sulphoxide reductase MsrA
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Antitoxin Xre/MbcA/ParS-like toxin-binding
Outer membrane protein assembly factor BamA
Large ribosomal subunit protein uL15/eL18
NIF system FeS cluster assembly NifU N-terminal
Glycosyl transferase family 3 N-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Manganese/iron superoxide dismutase C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Polysaccharide biosynthesis protein C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Helix-hairpin-helix DNA-binding motif class 1
Ribose-phosphate pyrophosphokinase N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Secretory immunoglobulin A-binding protein EsiB
Exonuclease VII large subunit C-terminal
ParB-related ThiF-related cassette protein E
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Outer membrane protein beta-barrel domain-containing protein
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
RlpA-like protein double-psi beta-barrel domain-containing protein
Thiosulphate:quinone oxidoreductase small subunit DoxA
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Signal recognition particle SRP54 helical bundle
Type I restriction modification DNA specificity
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Penicillin-binding protein transpeptidase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Type II secretion system protein GspE N-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Proton acceptor; for glutaminase activity
DNA polymerase III subunit delta C-terminal
Organic solvent tolerance-like N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Release factor glutamine methyltransferase N-terminal
Chromosomal replication initiator DnaA C-terminal
Flagellar hook-length control protein-like C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Ribulose bisphosphate carboxylase small subunit
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Electron transfer via tryptophanyl radical
Cytochrome b/b6 N-terminal region profile
Mannose-6-phosphate isomerase type II C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Interaction with polymerase core subunit RpoC
Could play a key role in the communication between the regulatory and the substrate sites
Phosphotransferase system enzyme I N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Glycine cleavage T-protein C-terminal barrel
Inner membrane protein YgaP-like transmembrane
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Thiol:disulfide interchange protein DsbD
TonB-dependent receptor-like beta-barrel domain-containing protein
Cytochrome oxidase subunit II transmembrane region profile
Glucosamine/galactosamine-6-phosphate isomerase
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
DNA-directed DNA polymerase family A palm
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Translation elongation factor P/YeiP central
Anthranilate synthase component I N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Chromosomal replication initiator protein DnaA
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Glycoside hydrolase family 57 N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
RNA 2-O ribose methyltransferase substrate binding
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Small ribosomal subunit protein uS4 N-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Alpha-amylase/4-alpha-glucanotransferase C-terminal
Alpha-amylase/4-alpha-glucanotransferase central
Important for substrate binding and specificity
Lysidine-tRNA(Ile) synthetase C-terminal
Prokaryotic-type class I peptide chain release factors
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Flagellar motor switch protein FliN-like C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Membrane fusion protein biotin-lipoyl like
NIF system FeS cluster assembly NifU C-terminal
Essential for prephenate dehydratase activity
HPr(Ser) kinase/phosphorylase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Cysteine sulfenic acid (-SOH) intermediate
Shikimate dehydrogenase substrate binding N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Survival protein SurE-like phosphatase/nucleotidase
Guanylate kinase/L-type calcium channel beta subunit
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
S-adenosylmethionine-dependent methyltransferase
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Polymerase/histidinol phosphatase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
PhoD-like phosphatase metallophosphatase
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel