Membrane insertase YidC/Oxa/ALB C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Major facilitator superfamily (MFS) profile
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Phosphodiester glycosidase domain-containing protein
PhoD-like phosphatase metallophosphatase
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Bacterial bifunctional deaminase-reductase C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Magnesium chelatase subunit H N-terminal
Photosystem II reaction center protein H
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Cyanobacterial aminoacyl-tRNA synthetase CAAD
Sulfatase-modifying factor enzyme domain-containing protein
Glucosamine/galactosamine-6-phosphate isomerase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Photosystem II reaction center protein X
Outer membrane protein beta-barrel domain-containing protein
BREX system Lon protease-like BrxL N-terminal
Bacterial type II secretion system protein E
Type II secretion system protein GspE N-terminal
Important for beta-aspartyl-AMP intermediate formation
Photosystem I reaction center subunit PsaK
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Homocysteine biosynthesis enzyme sulfur-incorporation
Glycosyltransferase subfamily 4-like N-terminal
RNA-binding protein Tab2-like N-terminal
RNA-binding protein Tab2/Atab2 C-terminal
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
RNA binding; important for wobble base 34 recognition
Pyridine nucleotide-disulphide oxidoreductase dimerisation
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Plastid lipid-associated protein/fibrillin conserved
ABC-type uncharacterised transport system
Mannose-6-phosphate isomerase type II C-terminal
CD-NTase-associated protein 12/Pycsar effector protein TIR
Phosphoadenosine phosphosulphate reductase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Tryptophan synthase beta chain-like PALP
PEP-CTERM protein-sorting domain-containing protein
Membrane fusion protein biotin-lipoyl like
Ribosomal RNA small subunit methyltransferase A
Urease accessory protein UreH-like transmembrane
DNA-directed DNA polymerase family A palm
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin)
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
Ribosomal RNA small subunit methyltransferase H
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
RND efflux pump membrane fusion protein barrel-sandwich
Schiff-base intermediate with substrate; via pyruvic acid
Glycosyl transferase family 28 C-terminal
Polypeptide-transport-associated ShlB-type
Aminoacyl-transfer RNA synthetases class-II family profile
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Anthranilate synthase component I N-terminal
Beta-lactamase hydrolase-like protein phosphatase-like
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Probable small ribosomal subunit protein cS23
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Nitrite/Sulfite reductase ferredoxin-like
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
UDP-N-acetylmuramoylalanine--D-glutamate ligase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
NIF system FeS cluster assembly NifU C-terminal
NIF system FeS cluster assembly NifU N-terminal
Photosystem I P700 chlorophyll a apoprotein A1
ABC transporter substrate-binding protein PnrA-like
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Peptidase M1 membrane alanine aminopeptidase
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Heme-copper oxidase subunit III family profile
Cytochrome b561 bacterial/Ni-hydrogenase
Solute-binding protein family 3/N-terminal
Nitrile hydratase alpha /Thiocyanate hydrolase gamma
Heat-inducible transcription repressor HrcA
Involved in Mg(2+) ion dislocation from EF-Tu
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
Photosystem II reaction center protein Y
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Peptide methionine sulphoxide reductase MsrA
Penicillin-binding protein transpeptidase
Glycine zipper 2TM domain-containing protein
Protein-glutamate methylesterase/protein-glutamine glutaminase
ABC-type glycine betaine transport system substrate-binding
Survival protein SurE-like phosphatase/nucleotidase
Acyl-CoA dehydrogenase/oxidase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
Leucyl/phenylalanyl-tRNA--protein transferase
NAD(P)H-quinone oxidoreductase subunit K
Glycogen debranching enzyme bacterial and archaeal type N-terminal
6-phosphogluconate dehydrogenase C-terminal
NAD(P)H-quinone oxidoreductase subunit 2
Gp5/Type VI secretion system Vgr protein OB-fold
Magnesium-protoporphyrin IX methyltransferase C-terminal
Crossover junction endodeoxyribonuclease RuvC
FMN-dependent NADH:quinone oxidoreductase
4-hydroxy-tetrahydrodipicolinate synthase
tRNA N6-adenosine threonylcarbamoyltransferase
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
15,16-dihydrobiliverdin:ferredoxin oxidoreductase
Fatty acid synthase subunit PfaD N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
Glycosyl transferase family 3 N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Pyruvate phosphate dikinase AMP/ATP-binding
Lipocalin-like domain-containing protein
Thioredoxin-like fold domain-containing protein
Photosystem I reaction center subunit IV
Type I restriction modification DNA specificity
Interaction with polymerase core subunit RpoC
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Acetylserotonin O-methyltransferase dimerisation
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Spore coat protein U domain-containing protein
Histidine-specific methyltransferase SAM-dependent
Probable transposase IS891/IS1136/IS1341
Prokaryotic-type class I peptide chain release factors
General stress protein FMN-binding split barrel
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Photosystem II reaction center protein Psb30
Cytochrome b6-f complex iron-sulfur subunit
Photosystem II reaction center protein Z
Type II restriction enzyme and methyltransferase RM.Eco57I-like
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Opioid growth factor receptor (OGFr) conserved
Phosphoribosylformylglycinamidine synthase subunit PurL
Cob(I)alamin adenosyltransferase N-terminal
Probable transcriptional regulatory protein Npun_R5651
Bacterial EndoU nuclease domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Ribose-phosphate pyrophosphokinase N-terminal
Ionotropic glutamate receptor C-terminal
Polysaccharide biosynthesis protein CapD-like
Menaquinone biosynthesis protein MenD middle
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
ATP-dependent Clp protease ATP-binding subunit ClpX
UDP-3-O-acyl-N-acetylglucosamine deacetylase
Alpha-D-phosphohexomutase alpha/beta/alpha
Cation-transporting P-type ATPase N-terminal
Resolvase/invertase-type recombinase catalytic
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Polymerase/histidinol phosphatase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Light-independent protochlorophyllide reductase subunit B-like C-terminal
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
4-hydroxy-tetrahydrodipicolinate reductase
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Cell envelope-related transcriptional attenuator
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
NAD(P)H-quinone oxidoreductase subunit J
DNA-binding transcriptional activator HetR
Does not affect KM for L-tryptophan or Vmax. Retains 63% of the original activity after 24 hours of incubation at 4 degrees Celsius. Exhibits 6-fold increase in Vmax, high stability and retains 90% of the original activity after 24 hours of incubation at 4 degrees Celsius; when associated with F-59; D-234 and N-296 (TrpDH-4mut).
Does not affect KM for L-tryptophan or Vmax. Retains 79% of the original activity after 24 hours of incubation at 4 degrees Celsius. Exhibits 6-fold increase in Vmax, high stability and retains 90% of the original activity after 24 hours of incubation at 4 degrees Celsius; when associated with F-59; G-168 and D-234 (TrpDH-4mut).
Does not affect KM for L-tryptophan. 1.77-fold increase in Vmax. Retains 29% of the original activity after 24 hours of incubation at 4 degrees Celsius. Exhibits 6-fold increase in Vmax, high stability and retains 90% of the original activity after 24 hours of incubation at 4 degrees Celsius; when associated with G-168; D-234 and N-296 (TrpDH-4mut).
Does not affect KM for L-tryptophan. 6.32-fold increase in Vmax. Retains 25% of the original activity after 24 hours of incubation at 4 degrees Celsius. Exhibits 6-fold increase in Vmax, high stability and retains 90% of the original activity after 24 hours of incubation at 4 degrees Celsius; when associated with F-59; G-168 and N-296 (TrpDH-4mut).
DNA-directed RNA polymerase subunit beta'
Cell division topological specificity factor
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Restriction endonuclease type I HsdR N-terminal
Photosystem II reaction center Psb28 protein
Contractile injection system tube protein N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Putative membrane protein insertion efficiency factor
Putative glycogen debranching enzyme N-terminal
Proton acceptor; for glutaminase activity
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
HicB-like antitoxin of toxin-antitoxin system
Pyridoxine/pyridoxamine 5'-phosphate oxidase
Glycoside hydrolase family 31 N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
N-(5'-phosphoribosyl)anthranilate isomerase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Transposon Tn7 transposition protein TnsD C-terminal
RNA polymerase sigma factor 70 region 4 type 2
N-acetylmuramic acid 6-phosphate etherase
TonB-dependent receptor-like beta-barrel
Chromosomal replication initiator protein DnaA
Schiff-base intermediate with substrate; via topaquinone
Imidazole glycerol phosphate synthase subunit HisH
Involved in allosteric activation by GTP
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
RlpA-like protein double-psi beta-barrel
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Protein O-mannosyl-transferase C-terminal four TM
Nitrogenase-stabilizing/protective protein NifW
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Organic solvent tolerance-like N-terminal
2-phytyl-1,4-naphtoquinone methyltransferase
Polysaccharide chain length determinant N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Methionyl-tRNA synthetase anticodon-binding
DNA-directed RNA polymerase subunit gamma
Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding
PEP-CTERM sorting domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
SUF system FeS cluster assembly SufBD N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Ferredoxin thioredoxin reductase alpha chain
Type I restriction enzyme R protein N-terminal
Ribulose bisphosphate carboxylase large chain
Glycosyl-hydrolase family 116 N-terminal
Glycosyl-hydrolase family 116 catalytic region
Glycosyltransferase 2-like prokaryotic type
Integral membrane protein YccS N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
NAD(P) transhydrogenase alpha subunit C-terminal
NAD(P)H-quinone oxidoreductase subunit O
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
Photosystem I reaction center subunit XI
Sodium/calcium exchanger membrane region
Photosystem II manganese-stabilizing polypeptide
Nitrogenase molybdenum-iron protein beta chain N-terminal
Arginine decarboxylase C-terminal helical
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Reversibly protonated during proton transport
Probable dual-specificity RNA methyltransferase RlmN
Release factor glutamine methyltransferase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Phycocyanobilin:ferredoxin oxidoreductase
Ribosomal protein uS12 methylthiotransferase RimO
Glutamate-1-semialdehyde 2,1-aminomutase
Photosystem II reaction center protein I
Transcription antitermination protein NusB
Could be important to modulate the pK values of the two catalytic cysteine residues
WGxxGxxG-CTERM domain-containing protein
YbaK/aminoacyl-tRNA synthetase-associated
Sugar fermentation stimulation protein homolog
Transposase IS116/IS110/IS902 C-terminal
Putative 8-amino-7-oxononanoate synthase
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Pyridoxamine 5'-phosphate oxidase putative
3-isopropylmalate dehydratase large subunit
Type IV secretion system coupling protein TraD DNA-binding
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Lantibiotic biosynthesis protein dehydration
2-oxoacid dehydrogenase acyltransferase catalytic
NAD(P)H-quinone oxidoreductase subunit N
NAD(P)H-quinone oxidoreductase subunit 1
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Phosphoribosylaminoimidazole-succinocarboxamide synthase
Lysozyme inhibitor LprI N-terminal domain-containing protein
Anaphase-promoting complex subunit 4-like WD40
DNA-directed RNA polymerase subunit omega
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Plays an important role in substrate specificity
O-(5'-phospho-DNA)-tyrosine intermediate
Cyclophilin-like domain-containing protein
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Inosine/uridine-preferring nucleoside hydrolase
Glycosyl hydrolases family 2 sugar binding
Probable 2-phosphosulfolactate phosphatase
Glycosyltransferase family 28 N-terminal
NAD(P)H-quinone oxidoreductase subunit L
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Phosphonate ABC transporter substrate-binding protein
Inward rectifier potassium channel C-terminal
NAD(P)H-quinone oxidoreductase subunit M
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
Polyribonucleotide nucleotidyltransferase
Schiff-base intermediate with acetaldehyde
NADH:ubiquinone oxidoreductase-like 20kDa subunit
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Photosystem I reaction center subunit IX
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Light-independent protochlorophyllide reductase subunit B
Cytochrome C biogenesis protein transmembrane
Polysaccharide biosynthesis protein C-terminal
Damage-control phosphatase ARMT1-like metal-binding
TrbG/VirB9 family P-type conjugative transfer protein
Putative pterin-4-alpha-carbinolamine dehydratase
ATP phosphoribosyltransferase regulatory subunit
vWA-MoxR associated protein middle region 1
Prepilin type IV endopeptidase peptidase
Essential for prephenate dehydratase activity
Phosphatidylglycerol lysyltransferase C-terminal
Holliday junction branch migration complex subunit RuvB
Glutamyl-tRNA(Gln) amidotransferase subunit A
UDP-3-O-acylglucosamine N-acyltransferase
Ribulose bisphosphate carboxylase small subunit
Phenylalanine--tRNA ligase alpha subunit
NAD(P)H-quinone oxidoreductase subunit H
No detectable effect on alkane biosynthesis activity in vivo.
Rubisco accumulation factor 1 C-terminal
Rubisco accumulation factor 1 alpha helical
Rubisco accumulation factor 1 helix turn helix
Septum formation inhibitor MinC C-terminal
Pseudouridine synthase I TruA alpha/beta
Dinitrogenase iron-molybdenum cofactor biosynthesis
Nucleophile; cysteine thiosulfonate intermediate
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Phosphorylase b kinase regulatory subunit alpha/beta C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Translation initiation factor beta propellor-like
NAD(P)H-quinone oxidoreductase subunit 3
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
UDP-N-acetylenolpyruvoylglucosamine reductase
Cytochrome b/b6 N-terminal region profile
Photosystem I reaction center subunit III
Ribosomal RNA small subunit methyltransferase G
Photosystem II reaction center protein K
3-phosphoshikimate 1-carboxyvinyltransferase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Bifunctional purine biosynthesis protein PurH
CRISPR-associated protein Cas6 C-terminal