Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Polysaccharide biosynthesis protein C-terminal
Methyl-coenzyme M reductase alpha subunit C-terminal
Methyl-coenzyme M reductase alpha subunit N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Bacterial transcription activator effector binding
Glycosyltransferase subfamily 4-like N-terminal
Glutamate synthase alpha subunit C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aspartate/homoserine dehydrogenase NAD-binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Large ribosomal subunit protein uL15/eL18
Aminoacyl-transfer RNA synthetases class-II family profile
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Solute-binding protein family 3/N-terminal
Transcription factor CBF/NF-Y/archaeal histone
Signal transduction histidine kinase 5TM receptor LytS transmembrane region
Translation elongation factor IF5A C-terminal
Type I restriction modification DNA specificity
Prepilin type IV endopeptidase peptidase
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Glycosyl transferase family 28 C-terminal
Tryptophan synthase beta chain-like PALP
Pyruvate/ketoisovalerate oxidoreductase catalytic
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Large ribosomal subunit protein uL10-like insertion
Molybdopterin cofactor biosynthesis C (MoaC)
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Methanogenesis regulatory protein FilR1 middle
H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase C-terminal
Methyl-coenzyme M reductase beta subunit C-terminal
Methyl-coenzyme M reductase beta subunit N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Carbamoyl-phosphate synthase small subunit N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
DNA mismatch repair proteins mutS family
Helix-hairpin-helix DNA-binding motif class 1
DNA-directed DNA polymerase family B multifunctional
Aminoacyl-tRNA synthetase class I anticodon-binding
Schiff-base intermediate with acetaldehyde
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Choloylglycine hydrolase/NAAA C-terminal
Glycosyl transferase family 3 N-terminal
SAM-dependent methyltransferase TRM5/TYW2-type
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
Hypoxanthine/guanine phosphoribosyltransferase
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
DNA polymerase alpha/delta/epsilon subunit B
Putative cytidyltransferase-related C-terminal region
TATA box binding protein associated factor (TAF) histone-like fold
Major facilitator superfamily (MFS) profile
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Exonuclease VII large subunit C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Type IV methyl-directed restriction enzyme EcoKMcrB subunit DNA-binding
Inosine monophosphate cyclohydrolase-like
Gamma-glutamylcyclotransferase AIG2-like
O-(5'-phospho-DNA)-tyrosine intermediate
Small ribosomal subunit protein uS4 N-terminal
F420-non-reducing hydrogenase iron-sulfur subunit D
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Sodium/calcium exchanger membrane region
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Tetrahydromethanopterin S-methyltransferase F subunit
Dihydroneopterin aldolase MtpD C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Spo11/DNA topoisomerase VI subunit A N-terminal
Tetrahydromethanopterin S-methyltransferase subunit A 2
Terminase large subunit gp17-like C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Alpha-D-phosphohexomutase alpha/beta/alpha
Restriction system protein Mrr-like N-terminal
Small ribosomal subunit protein uS15 N-terminal
Polymerase/histidinol phosphatase N-terminal
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Anthranilate synthase component I N-terminal
16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal
RNase L inhibitor RLI-like possible metal-binding
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Large ribosomal subunit protein uL6 alpha-beta
Phosphoribosylformylglycinamidine synthase linker
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Thiamine pyrophosphate enzyme TPP-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Bacterial type II secretion system protein E
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Thymidylate synthase/dCMP hydroxymethylase
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Sugar fermentation stimulation protein C-terminal
Schiff-base intermediate with dihydroxyacetone-P
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Alpha-(1,3)-fucosyltransferase FucT N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Cytoplasmic tRNA 2-thiolation protein 1 C-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Dinitrogenase iron-molybdenum cofactor biosynthesis
Survival protein SurE-like phosphatase/nucleotidase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Formylmethanofuran dehydrogenase subunit E
6-hydroxymethylpterin diphosphokinase MptE-like
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Removed in mature form; by autocatalysis
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
NIF system FeS cluster assembly NifU N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
tRNA nucleotidyltransferase substrate binding
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
Tetrahydromethanopterin S-methyltransferase subunit A 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Large ribosomal subunit protein uL2 C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Could be important to modulate the pK values of the two catalytic cysteine residues
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Plays an important role in substrate specificity
DNA-directed DNA polymerase family B exonuclease
Pseudouridine synthase I TruA alpha/beta
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Pyridoxamine 5'-phosphate oxidase putative
Gly-cisPro motif, important for rejection of L-amino acids
Cytochrome C biogenesis protein transmembrane
N6 adenine-specific DNA methyltransferase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase