Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Cytochrome c-type biogenesis protein CcmF C-terminal
DNA mismatch repair proteins mutS family
General stress protein FMN-binding split barrel
Tetrahydrodipicolinate-N-succinyltransferase chain A
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Peptidase S9 prolyl oligopeptidase catalytic
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Major facilitator superfamily (MFS) profile
Chromosomal replication initiator DnaA C-terminal
Tip attachment protein J domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
YbaK/aminoacyl-tRNA synthetase-associated
Bacterial bifunctional deaminase-reductase C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Bacterial DNA polymerase III alpha subunit NTPase
DNA polymerase helix-hairpin-helix motif
Inosine/uridine-preferring nucleoside hydrolase
Outer membrane protein beta-barrel domain-containing protein
Transcription regulator AsnC/Lrp ligand binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Haem-binding uptake Tiki superfamily ChaN domain-containing protein
Proton acceptor; for glutaminase activity
6-phosphogluconate dehydrogenase NADP-binding
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Electron transfer via tryptophanyl radical
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Exonuclease VII large subunit C-terminal
Tat pathway signal sequence domain protein
Activator of Hsp90 ATPase homologue 1-like C-terminal
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Flagellar motor switch protein FliN-like C-terminal
Methionyl-tRNA synthetase anticodon-binding
Type II secretion system protein GspC N-terminal
Fimbrial biogenesis outer membrane usher protein
Tryptophan synthase beta chain-like PALP
Interaction with polymerase core subunit RpoC
TonB-dependent receptor-like beta-barrel
Heme-copper oxidase subunit III family profile
Reversibly protonated during proton transport
Light-independent protochlorophyllide reductase subunit B-like C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
RNA polymerase sigma factor 70 region 4 type 2
Required for zinc-mediated homotetramerization and catalytic activity
SGNH hydrolase-type esterase domain-containing protein
RND efflux pump membrane fusion protein barrel-sandwich
Outer membrane protein assembly factor BamA
Peptidase M61 catalytic domain-containing protein
Glycosyltransferase family 28 N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase-like C-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Type I restriction enzyme R protein N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Cysteine sulfenic acid (-SOH) intermediate
Glycine cleavage T-protein C-terminal barrel
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Membrane fusion protein biotin-lipoyl like
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
DNA replication/recombination mediator RecO N-terminal
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
AB hydrolase-1 domain-containing protein
Survival protein SurE-like phosphatase/nucleotidase
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Histidine-specific methyltransferase SAM-dependent
Polysaccharide chain length determinant N-terminal
Putative auto-transporter adhesin head GIN
O-(5'-phospho-DNA)-tyrosine intermediate
Alpha-D-phosphohexomutase alpha/beta/alpha
Histidine phosphotransferase ChpT C-terminal
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Tail specific protease domain-containing protein
Aminoacyl-transfer RNA synthetases class-II family profile
Penicillin-binding protein transpeptidase
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Peptidase M1 membrane alanine aminopeptidase
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Protein-L-isoaspartate O-methyltransferase
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Solute-binding protein family 3/N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Superoxide dismutase copper/zinc binding
RNA 2-O ribose methyltransferase substrate binding
Pseudouridine synthase I TruA alpha/beta
S-adenosylmethionine-dependent methyltransferase
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Polysaccharide biosynthesis protein C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Anthranilate synthase component I N-terminal
Putative Flp pilus-assembly TadG-like N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Transglutaminase family protein cysteine peptidase BTLCP
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
RNA binding; important for wobble base 34 recognition
Putative glycogen debranching enzyme N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Resolvase/invertase-type recombinase catalytic
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Phosphoribosylformylglycinamidine synthase linker
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Photosynthetic reaction centre H subunit N-terminal
PHA accumulation regulator DNA-binding N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Opioid growth factor receptor (OGFr) conserved
Alanyl-transfer RNA synthetases family profile
N-end rule aminoacyl transferase C-terminal
Bacterial type II secretion system protein E
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Magnesium transporter MgtE intracellular
Carbamoyl-phosphate synthase small subunit N-terminal
peptide-methionine (R)-S-oxide reductase
Beta-lactamase hydrolase-like protein phosphatase-like
Twin-arginine translocation pathway signal
Translation elongation factor P/YeiP central
Right handed beta helix domain-containing protein
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Glycoamylase-like domain-containing protein
Small ribosomal subunit protein uS4 N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
PhoD-like phosphatase metallophosphatase
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
Prepilin type IV endopeptidase peptidase
S-adenosyl-L-homocysteine hydrolase NAD binding
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Rap1a immunity protein domain-containing protein
Glycosyl transferase family 3 N-terminal
Cytochrome c oxidase assembly protein CtaG
Polymerase/histidinol phosphatase N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Aspartate/homoserine dehydrogenase NAD-binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Type II secretion system protein GspI C-terminal
Magnesium chelatase subunit H N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
Flagella basal body P-ring formation protein FlgA C-terminal
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Oligogalacturonate lyase domain-containing protein
Glucosamine/galactosamine-6-phosphate isomerase
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Organic solvent tolerance-like N-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Cytochrome c oxidase subunit IV bacterial aa3 type
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-102)
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Polypeptide-transport-associated ShlB-type
Arabinogalactan endo-beta-1,4-galactanase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Endoribonuclease L-PSP/chorismate mutase-like
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
tRNA pseudouridylate synthase B C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Glycosyl-hydrolase 97 C-terminal oligomerisation
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Involved in allosteric activation by GTP
Peptide methionine sulfoxide reductase MsrA
Peptide methionine sulphoxide reductase MsrA
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Pyrroline-5-carboxylate reductase dimerisation
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Ribosomal RNA adenine methylase transferase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
SUF system FeS cluster assembly SufBD N-terminal
CASTOR/POLLUX/SYM8 ion channel conserved
Putative auto-transporter adhesin head GIN domain-containing protein
Beta-barrel assembly machine subunit BamF
DNA topoisomerase I catalytic core eukaryotic-type
Release factor glutamine methyltransferase N-terminal
Glucose/Sorbosone dehydrogenase domain-containing protein
Endolytic peptidoglycan transglycosylase RlpA
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Biopterin-dependent aromatic amino acid hydroxylase family profile
Large ribosomal subunit protein uL2 C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Prokaryotic-type class I peptide chain release factors
Magnesium-protoporphyrin IX methyltransferase C-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Glycosyl transferase family 28 C-terminal
Transcription elongation factor GreA/GreB C-terminal
Cobaltochelatase subunit CobS N-terminal
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal