Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Major facilitator superfamily (MFS) profile
Membrane insertase YidC/Oxa/ALB C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
RlpA-like protein double-psi beta-barrel
Gfo/Idh/MocA-like oxidoreductase N-terminal
Phosphoribosylformylglycinamidine synthase linker
RND efflux pump membrane fusion protein barrel-sandwich
Phosphotransferase system EIIB component type 2/3
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Large ribosomal subunit protein uL30-like ferredoxin-like fold
YbaK/aminoacyl-tRNA synthetase-associated
O-(3'-phospho-DNA)-tyrosine intermediate
Solute-binding protein family 3/N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
FAD-dependent oxidoreductase 2 FAD binding
Small ribosomal subunit protein uS4 N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
O-(5'-phospho-DNA)-tyrosine intermediate
Shikimate dehydrogenase substrate binding N-terminal
tRNA pseudouridylate synthase B C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Translation elongation factor P/YeiP central
Prepilin type IV endopeptidase peptidase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Cation-transporting P-type ATPase N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Penicillin-binding protein transpeptidase
DNA replication/recombination mediator RecO N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Bacterial type II secretion system protein E
Cell envelope-related transcriptional attenuator
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Prokaryotic-type class I peptide chain release factors
Phosphocysteine intermediate; for EIIB activity
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Large ribosomal subunit protein uL2 C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Exonuclease VII large subunit C-terminal
Chromosomal replication initiator DnaA C-terminal
Gram-positive cocci surface proteins LPxTG
Helix-hairpin-helix DNA-binding motif class 1
Tryptophan synthase beta chain-like PALP
Alanyl-transfer RNA synthetases family profile
RNA polymerase sigma factor 70 region 4 type 2
Thymidylate synthase/dCMP hydroxymethylase
Alpha-D-phosphohexomutase alpha/beta/alpha
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Ribose-phosphate pyrophosphokinase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Reversibly protonated during proton transport
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Schiff-base intermediate with acetaldehyde
Essential for prephenate dehydratase activity
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Phosphotransferase system enzyme I N-terminal
Interaction with polymerase core subunit RpoC
Carbamoyl-phosphate synthase small subunit N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Methionyl-tRNA synthetase anticodon-binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Large ribosomal subunit protein uL6 alpha-beta
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Large ribosomal subunit protein uL15/eL18
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Proton acceptor; for glutaminase activity
Putative regulatory protein FmdB Zinc ribbon
Glucose-6-phosphate isomerase prokaryote
Peptidase S9 prolyl oligopeptidase catalytic
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Glucosamine/galactosamine-6-phosphate isomerase
Mandelate racemase/muconate lactonizing enzyme C-terminal
SsuA/THI5-like domain-containing protein
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Polymerase/histidinol phosphatase N-terminal
Type I restriction modification DNA specificity
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Gly-cisPro motif, important for rejection of L-amino acids
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
2,4-diaminopentanoate dehydrogenase C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Could play a key role in the communication between the regulatory and the substrate sites
Thiamin pyrophosphokinase thiamin-binding
CobB/CobQ-like glutamine amidotransferase
Signal recognition particle SRP54 helical bundle
Inosine monophosphate cyclohydrolase-like
ABC transporter substrate-binding protein PnrA-like