Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Histidine-specific methyltransferase SAM-dependent
N-sulphoglucosamine sulphohydrolase C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Conserved virulence factor B-like winged helix
Peptidase M1 membrane alanine aminopeptidase
Aromatic amino acid beta-eliminating lyase/threonine aldolase
RND efflux pump membrane fusion protein barrel-sandwich
Major facilitator superfamily (MFS) profile
Glucose-6-phosphate isomerase prokaryote
UDP N-acetylglucosamine O-acyltransferase C-terminal
Shikimate dehydrogenase substrate binding N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Phosphatidic acid phosphatase type 2/haloperoxidase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
TonB-dependent receptor-like beta-barrel
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Important for beta-aspartyl-AMP intermediate formation
DNA mismatch repair proteins mutS family
Biopterin-dependent aromatic amino acid hydroxylase family profile
Glycosyl-hydrolase 97 C-terminal oligomerisation
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Polysaccharide biosynthesis protein CapD-like
Ribonucleotide reductase large subunit C-terminal
PhoD-like phosphatase metallophosphatase
Bacterial bifunctional deaminase-reductase C-terminal
Putative auto-transporter adhesin head GIN
Glucosamine/galactosamine-6-phosphate isomerase
O-(3'-phospho-DNA)-tyrosine intermediate
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Tryptophan synthase beta chain-like PALP
Cation-transporting P-type ATPase C-terminal
Cation-transporting P-type ATPase N-terminal
Type I restriction enzyme R protein N-terminal
Gamma-glutamylcyclotransferase AIG2-like
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Peptide methionine sulphoxide reductase MsrA
O-(5'-phospho-DNA)-tyrosine intermediate
Glycosyltransferase subfamily 4-like N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Interchain (with Cys-221); in linked form
Interchain (with Cys-55); in linked form
Aminoacyl-transfer RNA synthetases class-II family profile
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Pyruvate phosphate dikinase AMP/ATP-binding
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Signal transduction histidine kinase internal region
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Polymerase/histidinol phosphatase N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Nitrite/Sulfite reductase ferredoxin-like
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Alpha-N-acetylglucosaminidase C-terminal
Alpha-N-acetylglucosaminidase N-terminal
Alpha-N-acetylglucosaminidase tim-barrel
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Thymidylate synthase/dCMP hydroxymethylase
Mandelate racemase/muconate lactonizing enzyme C-terminal
Penicillin-binding protein transpeptidase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Transcription elongation factor GreA/GreB C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Translation elongation factor P/YeiP central
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Heme-copper oxidase subunit III family profile
Gly-cisPro motif, important for rejection of L-amino acids
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
SUF system FeS cluster assembly SufBD N-terminal
Anthranilate synthase component I N-terminal
Pseudouridine synthase I TruA alpha/beta
Large ribosomal subunit protein uL6 alpha-beta
Type IX secretion system membrane protein, PorP/SprF family
Glycosyl hydrolase family 98 putative carbohydrate-binding module
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glycoside hydrolase family 31 N-terminal
Plays an important role in substrate specificity
Type IX secretion system membrane protein PorP/SprF
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Sodium/calcium exchanger membrane region
Electron transfer via tryptophanyl radical
tRNA pseudouridylate synthase B C-terminal
Trigger factor ribosome-binding bacterial
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Transposase IS116/IS110/IS902 C-terminal
ABC-type uncharacterised transport system
Pyrroline-5-carboxylate reductase catalytic N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Transcription elongation factor GreA/GreB N-terminal
6-phosphogluconate dehydrogenase C-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Bacterial transcription activator effector binding
Butirosin biosynthesis protein H N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Sortilin N-terminal domain-containing protein
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Abolishes beta-porphyranase activity; when associated with M-120 and D-148.
Abolishes beta-porphyranase activity; when associated with M-120 and S-139.
Abolishes beta-porphyranase activity; when associated with S-139 and D-148.
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
3-keto-disaccharide hydrolase domain-containing protein
Prokaryotic-type class I peptide chain release factors
Cell division protein FtsQ/DivIB C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Pyrroline-5-carboxylate reductase dimerisation
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Beta-hexosaminidase bacterial type N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Release factor glutamine methyltransferase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
RNA 2-O ribose methyltransferase substrate binding
Lysidine-tRNA(Ile) synthetase C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Glycosyl-hydrolase family 116 N-terminal
Glycosyl-hydrolase family 116 catalytic region
Moybdenum cofactor oxidoreductase dimerisation
TRAP C4-dicarboxylate transport system permease DctM subunit
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Polysaccharide biosynthesis protein C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Formylmethanofuran dehydrogenase subunit E
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Aldehyde oxidase/xanthine dehydrogenase second molybdopterin binding
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
DNA topoisomerase I catalytic core eukaryotic-type
Phosphoadenosine phosphosulphate reductase
Carbamoyl-phosphate synthase small subunit N-terminal
Superoxide dismutase copper/zinc binding
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Alpha-L-glutamate ligase-related protein ATP-grasp
Aconitase A/isopropylmalate dehydratase small subunit swivel
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Type ISP restriction-modification enzyme LLaBIII C-terminal specificity
Sodium symporter small subunit predicted
Urease accessory protein UreH-like transmembrane
Aspartate/homoserine dehydrogenase NAD-binding
Small ribosomal subunit protein uS4 N-terminal
Cellulose-binding Sde182 nucleoside hydrolase-like
Peptide methionine sulfoxide reductase MsrA
Chromosomal replication initiator DnaA C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Secretion system C-terminal sorting domain-containing protein
Helix-hairpin-helix DNA-binding motif class 1
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding
Alpha-glycerophosphate oxidase C-terminal
Inner membrane protein YgaP-like transmembrane
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
N6 adenine-specific DNA methyltransferase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Membrane insertase YidC/Oxa/ALB C-terminal
Resolvase/invertase-type recombinase catalytic
Saccharopine dehydrogenase-like C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Large ribosomal subunit protein bL9 C-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Putative beta-lactamase-inhibitor-like PepSY-like
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Important for interaction with partner proteins
Glycosyl hydrolase family 30 beta sandwich
Alanyl-transfer RNA synthetases family profile
Quercetin 2,3-dioxygenase C-terminal cupin
Large ribosomal subunit protein uL2 C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Reversibly protonated during proton transport
S-adenosyl-L-homocysteine hydrolase NAD binding
Glycine cleavage T-protein C-terminal barrel
DNA-directed DNA polymerase family A palm
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Type I restriction modification DNA specificity
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Inosine/uridine-preferring nucleoside hydrolase
Gliding motility protein SprA N-terminal
Phosphomannose isomerase type I catalytic
Ribosome maturation factor RimP N-terminal
Beta-xylosidase C-terminal Concanavalin A-like
ATP-dependent DNA helicase RecG C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
NIF system FeS cluster assembly NifU C-terminal
Polysaccharide chain length determinant N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Thiosulphate:quinone oxidoreductase small subunit DoxA
NADH-rubredoxin oxidoreductase C-terminal
DNA replication/recombination mediator RecO N-terminal
Involved in tetramerization or stability of the tetramer
Glycosyl transferase family 3 N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Putative auto-transporter adhesin head GIN domain-containing protein
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Large ribosomal subunit protein uL15/eL18
Phosphatidate phosphatase APP1 catalytic
Survival protein SurE-like phosphatase/nucleotidase
Molybdopterin cofactor biosynthesis C (MoaC)
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal