Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Lytic transglycosylase superhelical linker
Heme-copper oxidase subunit III family profile
Aldehyde oxidase/xanthine dehydrogenase first molybdopterin binding
Aldehyde oxidase/xanthine dehydrogenase second molybdopterin binding
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Cob(I)alamin adenosyltransferase N-terminal
Lipocalin-like domain-containing protein
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
RND efflux pump membrane fusion protein barrel-sandwich
Major facilitator superfamily (MFS) profile
TonB-dependent receptor-like beta-barrel
Thymidylate synthase/dCMP hydroxymethylase
DNA polymerase III subunit delta C-terminal
Outer membrane protein assembly factor BamD
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
Phosphocysteine intermediate; for EIIB activity
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Membrane insertase YidC/Oxa/ALB C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Flagellar motor switch protein FliN-like C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Aminoacyl-transfer RNA synthetases class-II family profile
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Schiff-base intermediate with substrate; via pyruvic acid
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
NIF system FeS cluster assembly NifU C-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Tryptophan synthase beta chain-like PALP
Outer membrane protein assembly factor BamB
Essential for prephenate dehydratase activity
Glycine cleavage T-protein C-terminal barrel
Polymerase/histidinol phosphatase N-terminal
Interaction with polymerase core subunit RpoC
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Type III secretion system flagellar brake protein YcgR PilZN
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Acyl-CoA dehydrogenase/oxidase N-terminal
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Phosphatidic acid phosphatase type 2/haloperoxidase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Greasy slide, important in sugar transport
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
O-(5'-phospho-DNA)-tyrosine intermediate
Alpha-D-phosphohexomutase alpha/beta/alpha
Phosphoethanolamine transferase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Could play a key role in the communication between the regulatory and the substrate sites
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Phosphotransferase system enzyme I N-terminal
Fimbrial-type adhesion domain-containing protein
Phosphoadenosine phosphosulphate reductase
Gamma-glutamylcyclotransferase AIG2-like
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Outer membrane protein assembly factor BamE
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Molybdopterin cofactor biosynthesis C (MoaC)
Sugar fermentation stimulation protein C-terminal
Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Sodium/calcium exchanger membrane region
Aspartate/homoserine dehydrogenase NAD-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Cysteine sulfenic acid (-SOH) intermediate
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
D-galactose/methyl-galactoside binding periplasmic protein MglB
Mechanosensitive ion channel inner membrane
Flagellar assembly protein FliH/Type III secretion system HrpE
HicB-like antitoxin of toxin-antitoxin system
Helix-hairpin-helix DNA-binding motif class 1
Anthranilate synthase component I N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Involved in allosteric activation by GTP
DNA-directed RNA polymerase RpoA/D/Rpb3-type
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Major facilitator superfamily associated
ABC-type glycine betaine transport system substrate-binding
Cation-transporting P-type ATPase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Carbamoyl-phosphate synthase small subunit N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Large ribosomal subunit protein uL2 C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Peptide methionine sulphoxide reductase MsrA
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Penicillin-binding protein transpeptidase
Nitrite/Sulfite reductase ferredoxin-like
Translocation and assembly module subunit TamA
ATP synthase F1 complex delta/epsilon subunit N-terminal
Prokaryotic-type class I peptide chain release factors
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Essential for degradation by Lon protease
DnaJ homologue subfamily C member 28 conserved
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Methylguanine DNA methyltransferase ribonuclease-like
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Interaction with tRNA; Important for base-flipping
Pseudouridine synthase I TruA alpha/beta
Rap1a immunity protein domain-containing protein
Integral membrane protein YccS N-terminal
Exonuclease VII large subunit C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Important for beta-aspartyl-AMP intermediate formation
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Bacterial transcription activator effector binding
Large ribosomal subunit protein uL6 alpha-beta
Penicillin-binding protein activator LpoB
Negative modulator of initiation of replication SeqA N-terminal
Replication modulator SeqA C-terminal DNA-binding
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Proline utilization A proline dehydrogenase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Ribosomal RNA adenine methylase transferase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Activator of Hsp90 ATPase homologue 1-like C-terminal
Glycosyl transferase family 3 N-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
Transcriptional regulator SgrR N-terminal HTH
Interacts with tRNA; defines subfamily-specific binding signature
Flagellar motor switch protein FliN N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Regulator of nucleoside diphosphate kinase N-terminal
Acyl-CoA dehydrogenase C-terminal bacterial-type
Acyl-CoA dehydrogenase/oxidase C-terminal
Mannose-6-phosphate isomerase type II C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Superoxide dismutase copper/zinc binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
For 3-hydroxyacyl-CoA dehydrogenase activity
Could be important to modulate the pK values of the two catalytic cysteine residues
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Shikimate dehydrogenase substrate binding N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Reversibly protonated during proton transport
RNA polymerase sigma factor 70 region 4 type 2
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Outer membrane protein assembly factor BamA
Polysaccharide chain length determinant N-terminal
Polysaccharide biosynthesis protein C-terminal
Involved in tetramerization or stability of the tetramer
Molybdenum cofactor biosynthesis protein F N-terminal
RNA binding; important for wobble base 34 recognition
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Large ribosomal subunit protein bL25 L25
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Glycoside hydrolase family 31 N-terminal
Mediates proton transfer from the outer aqueous phase to the interior of the protein; involved in linking H(+) and Cl(-) transport
Mediates proton transfer from the protein to the inner aqueous phase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Outer-membrane lipoprotein carrier protein
Cytochrome b561 bacterial/Ni-hydrogenase
Cytochrome c-type biogenesis protein CcmF C-terminal
Small ribosomal subunit protein uS4 N-terminal
3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold
Translation elongation factor P/YeiP central
Periplasmic binding protein/LacI sugar binding
The binding site for the sugar molecule has not yet been established, but C-87 may be involved
Gly-cisPro motif, important for rejection of L-amino acids
Pyruvate dehydrogenase E1 component middle
Important for interaction with partner proteins
YbaK/aminoacyl-tRNA synthetase-associated
Appears to be important in orienting the phosphate for catalysis
Plays an important role in substrate specificity
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Inosine/uridine-preferring nucleoside hydrolase
Quercetin 2,3-dioxygenase C-terminal cupin
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
NIF system FeS cluster assembly NifU N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Plays an important role in discriminating NADH against NADPH
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Threonine/serine exporter-like N-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Release factor glutamine methyltransferase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Alpha-glycerophosphate oxidase C-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase