Trigger factor ribosome-binding bacterial
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
HupH hydrogenase expression protein C-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Polymerase/histidinol phosphatase N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
2-oxoglutarate carboxylase large subunit
Transcription factor NikR nickel binding C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Resolvase/invertase-type recombinase catalytic
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Dihydroorotate dehydrogenase electron transfer subunit iron-sulphur cluster binding
N6 adenine-specific DNA methyltransferase N-terminal
Type 2A encapsulin shell protein SrpI-like
Thiamine pyrophosphate enzyme TPP-binding
Dinitrogenase iron-molybdenum cofactor biosynthesis
Large ribosomal subunit protein uL15/eL18
Large ribosomal subunit protein uL2 C-terminal
Major facilitator superfamily (MFS) profile
Release factor glutamine methyltransferase N-terminal
Essential for prephenate dehydratase activity
RND efflux pump membrane fusion protein barrel-sandwich
Survival protein SurE-like phosphatase/nucleotidase
NIF system FeS cluster assembly NifU N-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Glycosyltransferase subfamily 4-like N-terminal
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
6-hydroxymethylpterin diphosphokinase MptE-like
Translation elongation factor P/YeiP central
Schiff-base intermediate with dihydroxyacetone-P
NADH:ubiquinone oxidoreductase-like 20kDa subunit
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Phosphoadenosine phosphosulphate reductase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Cytochrome b/b6 N-terminal region profile
Bacterial type II secretion system protein E
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Could be important to modulate the pK values of the two catalytic cysteine residues
Cation-transporting P-type ATPase N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
NIF system FeS cluster assembly NifU C-terminal
TonB-dependent receptor-like beta-barrel
Helix-hairpin-helix DNA-binding motif class 1
N(4)-bis(aminopropyl)spermidine synthase C-terminal
Polysaccharide biosynthesis protein CapD-like
Type II secretion system protein GspG C-terminal
Interaction with polymerase core subunit RpoC
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Cytochrome C biogenesis protein transmembrane
Nitrite/Sulfite reductase ferredoxin-like
Nucleophile; cysteine thiosulfonate intermediate
Membrane fusion protein biotin-lipoyl like
Membrane fusion protein biotin-lipoyl like domain-containing protein
Heme-copper oxidase subunit III family profile
2-oxoglutarate carboxylase small subunit
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Glycoside hydrolase family 57 N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
RNA binding; important for wobble base 34 recognition
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Positions MEP for the nucleophilic attack
Plays an important role in substrate specificity
Gly-cisPro motif, important for rejection of L-amino acids
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Fibronectin type-III domain-containing protein
Aldehyde ferredoxin oxidoreductase N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
ATP-grasp fold succinyl-CoA synthetase-type
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Inner membrane protein YgaP-like transmembrane
Pyridoxamine 5'-phosphate oxidase putative
ATP synthase F1 complex delta/epsilon subunit N-terminal
L-cysteine S-thiosulfotransferase subunit SoxA
TtsA-like Glycoside hydrolase family 108
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Phosphoribosylformylglycinamidine synthase linker
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Bacterial bifunctional deaminase-reductase C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Glycosyl transferase family 28 C-terminal
Penicillin-binding protein transpeptidase
Mannose-6-phosphate isomerase type II C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Cytochrome b561 bacterial/Ni-hydrogenase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Probable transposase IS891/IS1136/IS1341
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Prepilin type IV endopeptidase peptidase
UDP N-acetylglucosamine O-acyltransferase C-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pyruvate phosphate dikinase AMP/ATP-binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Almost loss of activity. Does not alter binding of the substrate analog Fe-UROIII.
Does not affect didecarboxysiroheme production. Cannot bind the substrate analog Fe-UROIII.
Does not affect didecarboxysiroheme production. Does not alter binding of the substrate analog Fe-UROIII.
Does not affect didecarboxysiroheme production. Shows a reduced ability to bind the substrate analog Fe-UROIII.
Loss of activity. Abolishes binding of the substrate analog Fe-UROIII.
Loss of activity. Does not alter binding of the substrate analog Fe-UROIII.
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Small ribosomal subunit protein uS4 N-terminal
Anthranilate synthase component I N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Proton acceptor; for glutaminase activity
Alanyl-transfer RNA synthetases family profile
AMP-activated protein kinase glycogen-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Type I restriction modification DNA specificity
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Moybdenum cofactor oxidoreductase dimerisation
S-adenosyl-L-homocysteine hydrolase NAD binding
Reversibly protonated during proton transport
Tryptophan synthase beta chain-like PALP
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Cytochrome b/b6 C-terminal region profile
Septum formation inhibitor MinC C-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Chromosomal replication initiator DnaA C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Thioredoxin-like fold domain-containing protein
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Cytochrome c-552/DMSO reductase-like haem-binding
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
DNA-directed DNA polymerase family A palm
Solute-binding protein family 3/N-terminal
Glycine cleavage T-protein C-terminal barrel
6-phosphogluconate dehydrogenase C-terminal
tRNA (guanine-N(1)-)-methyltransferase C-terminal
Important for guanine/8-oxoguanine distinction
Schiff-base intermediate with acetaldehyde
Bacterial repeat domain-containing protein
Pseudouridine synthase I TruA alpha/beta
Prokaryotic-type class I peptide chain release factors
Sigma 54 modulation/S30EA ribosomal protein C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Carbamoyl-phosphate synthase small subunit N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Nitrous oxide reductase accessory protein NosL
Important for interaction with partner proteins
Myo-inositol-1-phosphate synthase GAPDH-like
NADH-rubredoxin oxidoreductase C-terminal
RNA 2-O ribose methyltransferase substrate binding
Phosphatidic acid phosphatase type 2/haloperoxidase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Gfo/Idh/MocA-like oxidoreductase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Superoxide dismutase copper/zinc binding
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Glycosyl transferase family 3 N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Alpha-D-phosphohexomutase alpha/beta/alpha
Haem-binding uptake Tiki superfamily ChaN
Haem-binding uptake Tiki superfamily ChaN domain-containing protein
Terminase large subunit gp17-like C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Glycosyltransferase family 28 N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Sugar fermentation stimulation protein C-terminal
May play a role in metal incorporation in vivo
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Large ribosomal subunit protein uL6 alpha-beta
RlpA-like protein double-psi beta-barrel
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate