Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Polymerase/histidinol phosphatase N-terminal
Bacterial type II secretion system protein E
Membrane fusion protein biotin-lipoyl like
Probable transposase IS891/IS1136/IS1341
Glycosyl hydrolases family 2 sugar binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
DNA mismatch repair proteins mutS family
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Could play a key role in the communication between the regulatory and the substrate sites
RNA polymerase sigma factor 70 region 4 type 2
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Septum formation inhibitor MinC C-terminal
Positions MEP for the nucleophilic attack
Translation elongation factor P/YeiP central
Large ribosomal subunit protein uL2 C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Glycosyl transferase family 3 N-terminal
Transposase IS116/IS110/IS902 C-terminal
Glycosyl hydrolase family 98 putative carbohydrate-binding module
Glycosyl hydrolase family 98 putative carbohydrate-binding module domain-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Major facilitator superfamily (MFS) profile
Putative regulatory protein FmdB Zinc ribbon
Type III secretion system flagellar brake protein YcgR PilZN
DNA-directed DNA polymerase family A palm
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Sporulation stage IV protein A C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
X-X-X-Leu-X-X-Gly heptad repeat-containing protein
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Polysaccharide biosynthesis protein C-terminal
ABC transporter substrate-binding protein PnrA-like
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
NADH-rubredoxin oxidoreductase C-terminal
Plays an important role in substrate specificity
ATP-dependent DNA helicase RecG C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Sporulation transcription regulator WhiA N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Tryptophan RNA-binding attenuator protein
SUF system FeS cluster assembly SufBD N-terminal
Cytochrome C biogenesis protein transmembrane
RNA binding; important for wobble base 34 recognition
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Tryptophan synthase beta chain-like PALP
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Glycosyltransferase subfamily 4-like N-terminal
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Flagellar assembly protein FliH/Type III secretion system HrpE
Proton acceptor; for glutaminase activity
Signal transduction histidine kinase 5TM receptor LytS transmembrane region
Signal transduction histidine kinase internal region
Important for interaction with partner proteins
Dinitrogenase iron-molybdenum cofactor biosynthesis
Pyruvate/ketoisovalerate oxidoreductase catalytic
tRNA pseudouridylate synthase B C-terminal
Gamma-glutamylcyclotransferase AIG2-like
Penicillin-binding protein transpeptidase
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Aldehyde ferredoxin oxidoreductase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Glycoside hydrolase family 31 N-terminal
NIF system FeS cluster assembly NifU N-terminal
Glycoside hydrolase family 42 N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
N(4)-bis(aminopropyl)spermidine synthase C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Helix-hairpin-helix DNA-binding motif class 1
Aconitase A/isopropylmalate dehydratase small subunit swivel
Flagellar Assembly Protein A N-terminal region
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Important for beta-aspartyl-AMP intermediate formation
Carbamoyl-phosphate synthase small subunit N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Interchain (with Cys-216); in linked form
Interchain (with Cys-50); in linked form
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
CobB/CobQ-like glutamine amidotransferase
Flagellar hook-length control protein-like C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Involved in allosteric activation by GTP
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Large ribosomal subunit protein uL15/eL18
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Schiff-base intermediate with substrate; via pyruvic acid
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Alpha-D-phosphohexomutase alpha/beta/alpha
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Threonine/serine exporter-like N-terminal
PrcB C-terminal domain-containing protein
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
RNA 2-O ribose methyltransferase substrate binding
DNA replication/recombination mediator RecO N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Sodium/calcium exchanger membrane region
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Damage-control phosphatase ARMT1-like metal-binding
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Electron transfer flavoprotein alpha subunit C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Chromosomal replication initiator DnaA C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Phosphoribosylformylglycinamidine synthase linker
Could be important to modulate the pK values of the two catalytic cysteine residues
HicB-like antitoxin of toxin-antitoxin system
Large ribosomal subunit protein uL6 alpha-beta
Membrane insertase YidC/Oxa/ALB C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Schiff-base intermediate with D-ribose 5-phosphate
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Transcription regulator AsnC/Lrp ligand binding
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Formylmethanofuran dehydrogenase subunit E
Pyrimidine nucleoside phosphorylase C-terminal
Schiff-base intermediate with acetaldehyde
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Small ribosomal subunit protein uS4 N-terminal
Prepilin type IV endopeptidase peptidase
Large ribosomal subunit protein bL9 C-terminal
Prokaryotic-type class I peptide chain release factors
Alanyl-transfer RNA synthetases family profile
Release factor glutamine methyltransferase N-terminal
Flagellar motor switch protein FliN-like C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
O-(3'-phospho-DNA)-tyrosine intermediate
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Gly-cisPro motif, important for rejection of L-amino acids
ATP synthase F1 complex delta/epsilon subunit N-terminal
Pseudouridine synthase I TruA alpha/beta
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Anthranilate synthase component I N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Involved in ionization of N3 of dUMP, leading to its activation
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Conserved hypothetical protein CHP02679 N terminus
Transcription factor NikR nickel binding C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Putative amidase domain-containing protein
Peptidase S9 prolyl oligopeptidase catalytic
Phosphatidylglycerol lysyltransferase C-terminal
Dipicolinate synthase subunit A N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Reversibly protonated during proton transport
Solute-binding protein family 3/N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Cell envelope-related transcriptional attenuator
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Glycosyl hydrolase family 30 beta sandwich
Diacylglycerol glucosyltransferase N-terminal
Thiamin pyrophosphokinase thiamin-binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Phosphatidic acid phosphatase type 2/haloperoxidase