Tryptophan synthase beta chain-like PALP
Phosphocysteine intermediate; for EIIB activity
ATP-dependent dethiobiotin synthetase BioD
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
RNA binding; important for wobble base 34 recognition
Proton acceptor; for glutaminase activity
TonB-dependent receptor-like beta-barrel
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Anthranilate synthase component I N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Putative ATP-dependent zinc protease domain-containing protein
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Gfo/Idh/MocA-like oxidoreductase N-terminal
Major facilitator superfamily (MFS) profile
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Glycoside hydrolase family 31 N-terminal
Type VI secretion system IcmF C-terminal
3-isopropylmalate dehydratase small subunit
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Virulence factor membrane-bound polymerase C-terminal
3-isopropylmalate dehydratase large subunit
Crossover junction endodeoxyribonuclease RuvC
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
AB hydrolase-1 domain-containing protein
Ion-translocating oxidoreductase complex subunit B
Imidazole glycerol phosphate synthase subunit HisF
Polymerase/histidinol phosphatase N-terminal
Cellulose-binding Sde182 nucleoside hydrolase-like
Cellulose-binding Sde182 nucleoside hydrolase-like domain-containing protein
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical
Sodium/calcium exchanger membrane region
Solute-binding protein family 3/N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
ATP-dependent Clp protease ATP-binding subunit ClpX
Cysteine sulfenic acid (-SOH) intermediate
Membrane fusion protein biotin-lipoyl like
ABC transporter substrate-binding protein PnrA-like
Involved in allosteric activation by GTP
Phosphomannose isomerase type I catalytic
Important for substrate binding and specificity
Precorrin-2 dehydrogenase /sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Cobalt-precorrin-5B C(1)-methyltransferase
Probable transcriptional regulatory protein Tola_2714
N6 adenine-specific DNA methyltransferase N-terminal
Ribosomal RNA large subunit methyltransferase I
Alpha-D-phosphohexomutase alpha/beta/alpha
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Ribosomal RNA large subunit methyltransferase H
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Penicillin-binding protein transpeptidase
Antitoxin Xre/MbcA/ParS-like toxin-binding
Phosphotransferase system enzyme I N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
RNA 2-O ribose methyltransferase substrate binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Ribose-phosphate pyrophosphokinase N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Dinitrogenase iron-molybdenum cofactor biosynthesis
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Sulfite reductase [NADPH] hemoprotein beta-component
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD
Type I restriction modification DNA specificity
Schiff-base intermediate with substrate; via pyruvic acid
High frequency lysogenization protein HflD homolog
Reversibly protonated during proton transport
Bifunctional purine biosynthesis protein PurH
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Cation-transporting P-type ATPase N-terminal
UDP-3-O-acyl-N-acetylglucosamine deacetylase
Water stress and hypersensitive response
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Lysozyme inhibitor LprI N-terminal domain-containing protein
Periplasmic binding protein/LacI sugar binding
The binding site for the sugar molecule has not yet been established, but C-87 may be involved
Major facilitator superfamily associated
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Mandelate racemase/muconate lactonizing enzyme C-terminal
NIF system FeS cluster assembly NifU N-terminal
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Formate-dependent phosphoribosylglycinamide formyltransferase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Citrate transporter-like domain-containing protein
Bacterial type II secretion system protein E
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
Iron-sulfur cluster assembly protein CyaY
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Heme-copper oxidase subunit III family profile
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Enoyl-[acyl-carrier-protein] reductase [NADH]
Plays an important role in discriminating NADH against NADPH
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Probable septum site-determining protein MinC
Inner membrane protein YgaP-like transmembrane
Phosphoethanolamine transferase N-terminal
Negative modulator of initiation of replication
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Peptidase C39-like domain-containing protein
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
DNA-directed RNA polymerase subunit omega
Holliday junction branch migration complex subunit RuvB
Bacteriophage T7 Gp4 DNA primase/helicase N-terminal
4-hydroxy-tetrahydrodipicolinate reductase
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Outer membrane protein beta-barrel domain-containing protein
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Helix-hairpin-helix DNA-binding motif class 1
NIF system FeS cluster assembly NifU C-terminal
Polysaccharide biosynthesis protein C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Involved in Mg(2+) ion dislocation from EF-Tu
O-(5'-phospho-DNA)-tyrosine intermediate
DNA polymerase III subunit delta C-terminal
Menaquinone biosynthesis protein MenD middle
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Pyrimidine/purine nucleoside phosphorylase
Important for autoinhibition of adenylyltransferase activity
Shikimate dehydrogenase substrate binding N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Ion-translocating oxidoreductase complex subunit A
Phosphoadenosine phosphosulphate reductase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Plays an important role in substrate specificity
Nitrogenase molybdenum-iron protein beta chain N-terminal
Integral membrane protein YccS N-terminal
Succinate--CoA ligase [ADP-forming] subunit beta
Rap1a immunity protein domain-containing protein
Molybdopterin cofactor biosynthesis C (MoaC)
Gfo/Idh/MocA-like oxidoreductase C-terminal
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
Na(+)-translocating NADH-quinone reductase subunit E
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Chromosomal replication initiator protein DnaA
Na(+)-translocating NADH-quinone reductase subunit D
FMN-dependent NADH:quinone oxidoreductase
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Outer membrane protein assembly factor BamA
Deoxyuridine 5'-triphosphate nucleotidohydrolase
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Alanyl-transfer RNA synthetases family profile
Required for zinc-mediated homotetramerization and catalytic activity
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
3,4-dihydroxy-2-butanone 4-phosphate synthase
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
ABC-type transport auxiliary lipoprotein component
Important for beta-aspartyl-AMP intermediate formation
Phosphatidic acid phosphatase type 2/haloperoxidase
Pyrimidine nucleoside phosphorylase C-terminal
Glutamate-1-semialdehyde 2,1-aminomutase
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
DNA-directed RNA polymerase subunit alpha
Ion-translocating oxidoreductase complex subunit D
Ribosomal RNA large subunit methyltransferase M
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Na(+)-translocating NADH-quinone reductase subunit A
ATP synthase F1 complex delta/epsilon subunit N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Transposon Tn7 transposition protein TnsD C-terminal
Electron transfer via tryptophanyl radical
Cell division topological specificity factor
3-deoxy-manno-octulosonate cytidylyltransferase
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Aspartate carbamoyltransferase regulatory chain
Large-conductance mechanosensitive channel
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
RNA polymerase sigma factor 70 region 4 type 2
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
DNA-directed RNA polymerase subunit beta'
Prokaryotic-type class I peptide chain release factors
Interaction with polymerase core subunit RpoC
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
DNA mismatch repair proteins mutS family
Potassium-transporting ATPase potassium-binding subunit
Carbamoyl-phosphate synthase small subunit N-terminal
HicB-like antitoxin of toxin-antitoxin system
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Required for dimer formation and molybdate binding
Interacts with tRNA; defines subfamily-specific binding signature
N-acetyl-gamma-glutamyl-phosphate reductase
Thiol:disulfide interchange protein DsbD
Chromosome partition protein MukF C-terminal
Chromosome partition protein MukF middle
Chromosome partition protein MukF winged-helix
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Phosphoribosylformylglycinamidine cyclo-ligase
DNA polymerase III delta subunit C-terminal
Type 4 fimbrial biogenesis protein PilX N-terminal
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
TtsA-like Glycoside hydrolase family 108
Dual-specificity RNA methyltransferase RlmN
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Leucyl/phenylalanyl-tRNA--protein transferase
Pyruvate dehydrogenase E1 component middle
N-end rule aminoacyl transferase C-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Aspartate/homoserine dehydrogenase NAD-binding
Phenylalanine--tRNA ligase alpha subunit
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Peptide methionine sulphoxide reductase MsrA
Polysaccharide chain length determinant N-terminal
Ribosomal RNA large subunit methyltransferase E
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
O-(3'-phospho-DNA)-tyrosine intermediate
tRNA(Met) cytidine acetyltransferase TmcA N-terminal
tRNA(Met) cytidine acetyltransferase TmcA tRNA-binding
Purine nucleoside phosphorylase DeoD-type
D-galactose/methyl-galactoside binding periplasmic protein MglB
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Aminoacyl-transfer RNA synthetases class-II family profile
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Pyrroline-5-carboxylate reductase catalytic N-terminal
Outer membrane lipoprotein-sorting protein
Holliday junction branch migration complex subunit RuvA
Glycosyltransferase subfamily 4-like N-terminal
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
DNA-directed DNA polymerase family A palm
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
NADPH-dependent 7-cyano-7-deazaguanine reductase
Mannose-6-phosphate isomerase type II C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Conserved virulence factor B-like winged helix
Pyrroline-5-carboxylate reductase dimerisation
Nucleophile; cysteine thiosulfonate intermediate
Type II secretion system protein GspG C-terminal
Integrating conjugative element protein, PFL_4710 family
3-methyl-2-oxobutanoate hydroxymethyltransferase
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
ABC-type transport auxiliary lipoprotein component domain-containing protein
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Putative conjugal transfer nickase/helicase TraI C-terminal
tRNA/tmRNA (uracil-C(5))-methyltransferase
Pimeloyl-[acyl-carrier protein] methyl ester esterase
Potassium-transporting ATPase ATP-binding subunit
Essential for prephenate dehydratase activity
3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-98)
3-phosphoshikimate 1-carboxyvinyltransferase
Transcription antitermination protein NusB
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Alginate biosynthesis protein AlgX C-terminal carbohydrate-binding module
Putative regulatory protein FmdB Zinc ribbon
UDP-3-O-acylglucosamine N-acyltransferase
Periplasmic copper-binding protein NosD beta helix
Polyribonucleotide nucleotidyltransferase
tRNA N6-adenosine threonylcarbamoyltransferase
Gly-cisPro motif, important for rejection of L-amino acids
Ribosomal RNA small subunit methyltransferase H
Integrating conjugative element membrane protein
Cob(I)alamin adenosyltransferase N-terminal
ATP-dependent protease ATPase subunit HslU
Exopolysaccharide biosynthesis protein YbjH
Type II secretion system protein GspC N-terminal