Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Bacterial type II secretion system protein E
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Helix-hairpin-helix DNA-binding motif class 1
Aminoacyl-transfer RNA synthetases class-II family profile
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Major facilitator superfamily (MFS) profile
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Terminase large subunit-like endonuclease
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Prokaryotic-type class I peptide chain release factors
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Solute-binding protein family 3/N-terminal
Ribosomal RNA small subunit methyltransferase E methyltransferase
Membrane fusion protein biotin-lipoyl like
Activator of Hsp90 ATPase homologue 1-like C-terminal
Penicillin-binding protein transpeptidase
Glycoside hydrolase family 42 N-terminal
Methylguanine DNA methyltransferase ribonuclease-like
Gfo/Idh/MocA-like oxidoreductase N-terminal
Flagellar motor switch protein FliN-like C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Phosphotransferase system enzyme I N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Phosphoribosylformylglycinamidine synthase linker
Pyridoxamine 5'-phosphate oxidase putative
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Cell envelope-related transcriptional attenuator
Carbohydrate-binding CenC domain protein
Trigger factor ribosome-binding bacterial
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Polymerase/histidinol phosphatase N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Anthranilate synthase component I N-terminal
Flagellar basal body rod protein N-terminal
DNA replication/recombination mediator RecO N-terminal
Removed in mature form; by autocatalysis
6-phosphogluconate dehydrogenase C-terminal
Cytochrome C biogenesis protein transmembrane
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Resolvase/invertase-type recombinase catalytic
Membrane insertase YidC/Oxa/ALB C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Glycoside-hydrolase family GH114 TIM-barrel
Phosphatidate phosphatase APP1 catalytic
ABC transporter substrate-binding protein PnrA-like
Important for substrate specificity; cannot use PPi as phosphoryl donor
NADH:flavin oxidoreductase/NADH oxidase N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Cytochrome oxidase subunit II copper A binding
Pseudouridine synthase I TruA alpha/beta
Alpha-D-phosphohexomutase alpha/beta/alpha
Alpha-glycerophosphate oxidase C-terminal
Excalibur calcium-binding domain-containing protein
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Tryptophan synthase beta chain-like PALP
non-reducing end alpha-L-arabinofuranosidase
Flagellar basal-body/hook protein C-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Carbamoyl-phosphate synthase small subunit N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
DNA topoisomerase I catalytic core eukaryotic-type
Gfo/Idh/MocA-like oxidoreductase C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Phosphoadenosine phosphosulphate reductase
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Bacterial Ig-like domain-containing protein
Pyruvate phosphate dikinase AMP/ATP-binding
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
N-acetylneuraminic acid synthase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Glycosyltransferase subfamily 4-like N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Release factor glutamine methyltransferase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Heme-copper oxidase subunit III family profile
O-(3'-phospho-DNA)-tyrosine intermediate
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Essential for prephenate dehydratase activity
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Transposase IS116/IS110/IS902 C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Pyruvate dehydrogenase E1 component middle
Small ribosomal subunit protein uS4 N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Putative regulatory protein FmdB Zinc ribbon
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Nucleophile; cysteine thiosulfonate intermediate
Nitrite/Sulfite reductase ferredoxin-like
Thymidylate synthase/dCMP hydroxymethylase
Heat-inducible transcription repressor HrcA C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Phosphomannose isomerase type I catalytic
Right handed beta helix domain-containing protein
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Carbohydrate-binding domain-containing protein
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Large ribosomal subunit protein uL2 C-terminal
Schiff-base intermediate with acetaldehyde
BAAT/Acyl-CoA thioester hydrolase C-terminal
Prepilin type IV endopeptidase peptidase
Alanyl-transfer RNA synthetases family profile
Glycine cleavage T-protein C-terminal barrel
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Bacterial transcription activator effector binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Large ribosomal subunit protein uL6 alpha-beta
Phosphatidic acid phosphatase type 2/haloperoxidase
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Pyrimidine nucleoside phosphorylase C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
NIF system FeS cluster assembly NifU N-terminal
Threonine/serine exporter-like N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Plays an important role in substrate specificity
Endoribonuclease L-PSP/chorismate mutase-like
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
ABC-type glycine betaine transport system substrate-binding
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Polysaccharide biosynthesis protein C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Could play a key role in the communication between the regulatory and the substrate sites
Beta-hexosaminidase bacterial type N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Cation-transporting P-type ATPase N-terminal
Translation elongation factor P/YeiP central
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Nicotinate phosphoribosyltransferase N-terminal
Centromere-binding protein ParB C-terminal
Moves into active site upon enzyme activation, plays a role in electron transfer
Glycosyl transferase family 3 N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Peptide methionine sulphoxide reductase MsrA
Electron transfer via tryptophanyl radical
Interaction with polymerase core subunit RpoC
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Glycosyl transferase family 28 C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Putative oxidoreductase/dehydrogenase Rossmann-like
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Sporulation transcription regulator WhiA N-terminal
Glycoside hydrolase family 31 N-terminal
Flagellar hook-length control protein-like C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
RNA 2-O ribose methyltransferase substrate binding
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Peptidase M1 membrane alanine aminopeptidase
Chromosomal replication initiator DnaA C-terminal
Large ribosomal subunit protein uL15/eL18
Ribosomally synthesized peptide with SipW-like signal peptide
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta