Phosphatidic acid phosphatase type 2/haloperoxidase
Alpha-D-phosphohexomutase alpha/beta/alpha
Bacterial type II secretion system protein E
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Major facilitator superfamily (MFS) profile
Cation-transporting P-type ATPase N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Extracellular endo-alpha-(1->5)-L-arabinanase C-terminal
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Phenol hydroxylase C-terminal dimerisation
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Periplasmic binding protein domain-containing protein
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Sporulation transcription regulator WhiA N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Peptidase M1 membrane alanine aminopeptidase
Could be important to modulate the pK values of the two catalytic cysteine residues
Flagellar assembly protein FliH/Type III secretion system HrpE
Ribose-phosphate pyrophosphokinase N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
FAD-dependent oxidoreductase 2 FAD binding
Shikimate dehydrogenase substrate binding N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Endoribonuclease L-PSP/chorismate mutase-like
RNA polymerase sigma factor 70 region 4 type 2
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Pyridoxamine 5'-phosphate oxidase putative
Pyruvate phosphate dikinase AMP/ATP-binding
Flagellar motor switch protein FliN-like C-terminal
Right handed beta helix domain-containing protein
Gfo/Idh/MocA-like oxidoreductase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Acyltransferase MbtK/IucB-like conserved
Bacterial bifunctional deaminase-reductase C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Anaphase-promoting complex subunit 4-like WD40
Phosphoadenosine phosphosulphate reductase
Ribosomal RNA small subunit methyltransferase E methyltransferase
Activator of Hsp90 ATPase homologue 1-like C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Solute-binding protein family 3/N-terminal
Important for substrate specificity; cannot use PPi as phosphoryl donor
Glycoside hydrolase family 42 N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Peptide methionine sulphoxide reductase MsrA
DNA topoisomerase I catalytic core eukaryotic-type
Alpha-glycerophosphate oxidase C-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Chemotaxis methyl-accepting receptor HlyB-like 4HB MCP
Aminoacyl-transfer RNA synthetases class-II family profile
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Penicillin-binding protein transpeptidase
Phosphatidate phosphatase APP1 catalytic
6-phosphogluconate dehydrogenase C-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Putative host cell surface-exposed lipoprotein Ltp-like HTH region
ABC-type glycine betaine transport system substrate-binding
Could play a key role in the communication between the regulatory and the substrate sites
Positions MEP for the nucleophilic attack
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Membrane fusion protein biotin-lipoyl like
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Carbohydrate-binding domain-containing protein
Glycoside hydrolase family 31 N-terminal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Anthranilate synthase component I N-terminal
Polymerase/histidinol phosphatase N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Proton acceptor; for glutaminase activity
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Flagellar hook-length control protein-like C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Phosphotransferase system enzyme I N-terminal
Prokaryotic-type class I peptide chain release factors
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Tryptophan synthase beta chain-like PALP
Peptidoglycan recognition protein family
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Polysaccharide chain length determinant N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
LPXTG-motif cell wall anchor domain protein
Prepilin type IV endopeptidase peptidase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Beta-hexosaminidase bacterial type N-terminal
Chromosomal replication initiator DnaA C-terminal
NIF system FeS cluster assembly NifU N-terminal
Transcriptional regulator LacI/GalR-like sensor
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Glycosyltransferase subfamily 4-like N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Cytochrome oxidase subunit II copper A binding
YbaK/aminoacyl-tRNA synthetase-associated
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Membrane insertase YidC/Oxa/ALB C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
BAAT/Acyl-CoA thioester hydrolase C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Essential for prephenate dehydratase activity
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Peptidase S9 prolyl oligopeptidase catalytic
Type II restriction enzyme and methyltransferase RM.Eco57I-like
NADH:ubiquinone oxidoreductase 30kDa subunit
Glycerophosphoryl diester phosphodiesterase membrane
Beta-xylosidase C-terminal Concanavalin A-like
Resolvase/invertase-type recombinase catalytic
Na+/H+ antiporter MnhB subunit-related protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Pseudouridine synthase I TruA alpha/beta
Thymidylate synthase/dCMP hydroxymethylase
Periplasmic copper-binding protein NosD beta helix
Periplasmic copper-binding protein NosD beta helix domain-containing protein
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glucose-methanol-choline oxidoreductase C-terminal
Exonuclease VII large subunit C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
General stress protein FMN-binding split barrel
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Moves into active site upon enzyme activation, plays a role in electron transfer
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Nuclear transport factor 2 family protein
Electron transfer via tryptophanyl radical
Phosphocysteine intermediate; for EIIB activity
Glucose-methanol-choline oxidoreductase N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Helix-hairpin-helix DNA-binding motif class 1
Phosphoribosylformylglycinamidine synthase linker
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glycoside hydrolase GH146 substrate-binding
Flagellar hook-basal body complex protein FliE
RNA 2-O ribose methyltransferase substrate binding
Glycosyl transferase family 3 N-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
Putative oxidoreductase/dehydrogenase Rossmann-like
DNA replication/recombination mediator RecO N-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Arabinogalactan endo-beta-1,4-galactanase
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Methionyl-tRNA synthetase anticodon-binding
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Pyrroline-5-carboxylate reductase dimerisation
Threonine/serine exporter-like N-terminal
Alpha galactosidase C-terminal beta sandwich
SUF system FeS cluster assembly SufBD N-terminal
ABC transporter substrate-binding protein PnrA-like
Large ribosomal subunit protein uL2 C-terminal
Schiff-base intermediate with acetaldehyde
Gp5/Type VI secretion system Vgr protein OB-fold
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Glucosamine/galactosamine-6-phosphate isomerase
Translation elongation factor P/YeiP central
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
Carbamoyl-phosphate synthase small subunit N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Interaction with polymerase core subunit RpoC
Ionotropic glutamate receptor C-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Heat-inducible transcription repressor HrcA C-terminal
Protein O-mannosyl-transferase C-terminal four TM
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Release factor glutamine methyltransferase N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Cell envelope-related transcriptional attenuator
Plays an important role in substrate specificity
Alanyl-transfer RNA synthetases family profile
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Small ribosomal subunit protein uS4 N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Large ribosomal subunit protein uL15/eL18
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Heme-copper oxidase subunit III family profile
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Cell division protein FtsQ/DivIB C-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Pyruvate dehydrogenase E1 component middle