Aminoacyl-transfer RNA synthetases class-II family profile
Acetylserotonin O-methyltransferase dimerisation
Aconitase A/isopropylmalate dehydratase small subunit swivel
Type III secretion system flagellar brake protein YcgR PilZN
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Glycosyl transferase family 3 N-terminal
Ribosome maturation factor RimP N-terminal
Bacterial type II secretion system protein E
TRAP C4-dicarboxylate transport system permease DctM subunit
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Bacterial transcription activator effector binding
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
RND efflux pump membrane fusion protein barrel-sandwich
Inosine/uridine-preferring nucleoside hydrolase
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Alanyl-transfer RNA synthetases family profile
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Cation-transporting P-type ATPase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Polymerase/histidinol phosphatase N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Mannose-6-phosphate isomerase type II C-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Alpha-(1,3)-fucosyltransferase FucT N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
L-seryl-tRNA selenium transferase N-terminal
Diacylglycerol glucosyltransferase N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Flagellar Assembly Protein A N-terminal region
Phosphatidylglycerol lysyltransferase C-terminal
Type II secretion system protein GspG C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Thiamin pyrophosphokinase thiamin-binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
N-acetylneuraminic acid synthase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Saccharopine dehydrogenase-like C-terminal
Major facilitator superfamily (MFS) profile
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Schiff-base intermediate with substrate; via pyruvic acid
ABC transporter substrate-binding protein PnrA-like
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Schiff-base intermediate with acetaldehyde
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
N6 adenine-specific DNA methyltransferase N-terminal
Thiamine pyrophosphate enzyme TPP-binding
Gfo/Idh/MocA-like oxidoreductase N-terminal
S-adenosylmethionine-dependent methyltransferase
Survival protein SurE-like phosphatase/nucleotidase
Mandelate racemase/muconate lactonizing enzyme C-terminal
Flagellar motor switch protein FliN-like C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Could play a key role in the communication between the regulatory and the substrate sites
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Involved in allosteric activation by GTP
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Formylmethanofuran dehydrogenase subunit E
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
Leucine-binding protein domain-containing protein
HicB-like antitoxin of toxin-antitoxin system
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Phosphotransferase system enzyme I N-terminal
Penicillin-binding protein transpeptidase
Involved in ionization of N3 of dUMP, leading to its activation
Magnesium transporter MgtE intracellular
Molybdopterin cofactor biosynthesis C (MoaC)
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Pyruvate phosphate dikinase AMP/ATP-binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Tryptophan synthase beta chain-like PALP
Large ribosomal subunit protein uL6 alpha-beta
Gly-cisPro motif, important for rejection of L-amino acids
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glycoside hydrolase family 57 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Siroheme decarboxylase AsnC-like ligand binding
Type I restriction modification DNA specificity
Flagellar assembly protein FliH/Type III secretion system HrpE
Large ribosomal subunit protein uL2 C-terminal
Schiff-base intermediate with D-ribose 5-phosphate
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Could be important to modulate the pK values of the two catalytic cysteine residues
RNA binding; important for wobble base 34 recognition
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Meso-diaminopimelate D-dehydrogenase C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Aldehyde ferredoxin oxidoreductase N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Type II secretion system protein GspE N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Prepilin type IV endopeptidase peptidase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
UDP N-acetylglucosamine O-acyltransferase C-terminal
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Curli production assembly/transport component CsgG
NADH:ubiquinone oxidoreductase-like 20kDa subunit
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Large ribosomal subunit protein uL15/eL18
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Small ribosomal subunit protein uS4 N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Helix-hairpin-helix DNA-binding motif class 1
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Shikimate dehydrogenase substrate binding N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
DNA-directed DNA polymerase family A palm
Translation elongation factor P/YeiP central
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Urease accessory protein UreH-like transmembrane
Pyrimidine nucleoside phosphorylase C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Ysc84 actin-binding domain-containing protein
NIF system FeS cluster assembly NifU N-terminal
Plays an important role in substrate specificity
Essential for prephenate dehydratase activity
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
NIF system FeS cluster assembly NifU C-terminal
Pyridoxamine 5'-phosphate oxidase putative
ATP-dependent DNA helicase RecG C-terminal
Membrane fusion protein biotin-lipoyl like
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Calcium/calmodulin-dependent protein kinase II association-domain
tRNA (guanine-N(1)-)-methyltransferase C-terminal
Exonuclease VII large subunit C-terminal
Organic solvent tolerance-like N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Release factor glutamine methyltransferase N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Dinitrogenase iron-molybdenum cofactor biosynthesis
Lipopolysaccharide assembly protein A domain-containing protein
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Polysaccharide biosynthesis protein CapD-like
Na+-translocating membrane potential-generating system MpsC
Septum formation inhibitor MinC C-terminal
Trigger factor ribosome-binding bacterial
O-(5'-phospho-DNA)-tyrosine intermediate
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Prokaryotic-type class I peptide chain release factors
NADH-ubiquinone oxidoreductase 51kDa subunit FMN-binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Sugar fermentation stimulation protein C-terminal
Transcription factor NikR nickel binding C-terminal
Pseudouridine synthase I TruA alpha/beta
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation