Phosphotransferase system enzyme I N-terminal
Glycosyl hydrolase-like 10 domain-containing protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Peptidase S9 prolyl oligopeptidase catalytic
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Major facilitator superfamily (MFS) profile
Phosphoinositide phospholipase C, Ca2+-dependent
Glycosyltransferase subfamily 4-like N-terminal
Bacterial type II secretion system protein E
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Flagellar motor switch protein FliG C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Carboxypeptidase regulatory-like domain-containing protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type
3-keto-disaccharide hydrolase domain-containing protein
PEP-CTERM protein-sorting domain-containing protein
N,N-dimethylformamidase beta subunit-like C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Tryptophan synthase beta chain-like PALP
Pyruvate phosphate dikinase AMP/ATP-binding
Glucosamine/galactosamine-6-phosphate isomerase
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Pyrimidine nucleoside phosphorylase C-terminal
Urease accessory protein UreH-like transmembrane
Polymerase/histidinol phosphatase N-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
Large ribosomal subunit protein uL15/eL18
RNA polymerase sigma factor 70 region 4 type 2
Important for beta-aspartyl-AMP intermediate formation
Nitrite/Sulfite reductase ferredoxin-like
RND efflux pump membrane fusion protein barrel-sandwich
Positions MEP for the nucleophilic attack
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Helix-hairpin-helix DNA-binding motif class 1
N-end rule aminoacyl transferase C-terminal
S-adenosylmethionine-dependent methyltransferase
ABC-type uncharacterised transport system
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Aminoacyl-transfer RNA synthetases class-II family profile
Glycosyltransferase RgtA/B/C/D-like domain-containing protein
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Periplasmic binding protein domain-containing protein
Endoribonuclease L-PSP/chorismate mutase-like
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Heme-copper oxidase subunit III family profile
Ribosomal RNA adenine methylase transferase N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Schiff-base intermediate with substrate; via pyruvic acid
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
ATP-grasp fold succinyl-CoA synthetase-type
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Peptide methionine sulphoxide reductase MsrA
Prokaryotic-type class I peptide chain release factors
Cation-transporting P-type ATPase N-terminal
Iron dependent repressor metal binding and dimerisation
DNA-directed DNA polymerase family A palm
Peptidase M1 membrane alanine aminopeptidase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Glycosyl hydrolase family 98 putative carbohydrate-binding module
UDP N-acetylglucosamine O-acyltransferase C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Gly-cisPro motif, important for rejection of L-amino acids
Resolvase/invertase-type recombinase catalytic
Methionyl-tRNA synthetase anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Galactose-1-phosphate uridyl transferase N-terminal
Alanyl-transfer RNA synthetases family profile
NIF system FeS cluster assembly NifU C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Cytochrome b/b6 N-terminal region profile
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Membrane fusion protein biotin-lipoyl like
O-(3'-phospho-DNA)-tyrosine intermediate
ATP synthase F1 complex delta/epsilon subunit N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Restriction system protein Mrr-like N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Methylene-tetrahydromethanopterin dehydrogenase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
DNA replication/recombination mediator RecO N-terminal
Glycine cleavage T-protein C-terminal barrel
Tetratricopeptide TPR_1 repeat-containing protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
O-(5'-phospho-DNA)-tyrosine intermediate
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Polysaccharide chain length determinant N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Phosphomannose isomerase type I catalytic
Alpha-amylase/4-alpha-glucanotransferase C-terminal
Alpha-amylase/4-alpha-glucanotransferase central
Glycoside hydrolase family 57 N-terminal
Release factor glutamine methyltransferase N-terminal
Prepilin type IV endopeptidase peptidase
Proton acceptor; for glutaminase activity
Pyridine nucleotide-disulphide oxidoreductase dimerisation
SUF system FeS cluster assembly SufBD N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Trigger factor ribosome-binding bacterial
Phosphatidic acid phosphatase type 2/haloperoxidase
Small ribosomal subunit protein uS4 N-terminal
Formylmethanofuran dehydrogenase subunit E
CobB/CobQ-like glutamine amidotransferase
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Chromosomal replication initiator DnaA C-terminal
Neutral/alkaline non-lysosomal ceramidase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Ribosomal RNA small subunit methyltransferase E methyltransferase
Formamidopyrimidine-DNA glycosylase catalytic
RNA binding; important for wobble base 34 recognition
6-phosphogluconate dehydrogenase C-terminal
Schiff-base intermediate with acetaldehyde
Large ribosomal subunit protein uL2 C-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Transcription regulator HTH AraC- type ligand binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Putative exodeoxyribonuclease 8 PDDEXK-like
Terminase large subunit GpA endonuclease
Aminoacyl-tRNA synthetase class I anticodon-binding
Neutral/alkaline non-lysosomal ceramidase N-terminal domain-containing protein
Anthranilate synthase component I N-terminal
Translation elongation factor P/YeiP central
Alpha-D-phosphohexomutase alpha/beta/alpha
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
PhoD-like phosphatase metallophosphatase
Cytochrome C Planctomycete-type domain-containing protein
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase