Major facilitator superfamily (MFS) profile
Transposase IS116/IS110/IS902 C-terminal
ABC-type transport auxiliary lipoprotein component
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Aminoacyl-transfer RNA synthetases class-II family profile
Membrane fusion protein biotin-lipoyl like
Ribose-phosphate pyrophosphokinase N-terminal
Tryptophan synthase beta chain-like PALP
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Flagellar hook-length control protein-like C-terminal
Penicillin-binding protein transpeptidase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Bacterial collagen-like protein middle domain-containing protein
Ysc84 actin-binding domain-containing protein
Cobaltochelatase subunit CobS N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Proton acceptor; for glutaminase activity
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Interaction with polymerase core subunit RpoC
Hypersensitivity response secretion-like HrpJ
Resolvase/invertase-type recombinase catalytic
Plays an important role in substrate specificity
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Required for dimer formation and molybdate binding
O-(3'-phospho-DNA)-tyrosine intermediate
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Type II secretion system protein GspC N-terminal domain-containing protein
Schiff-base intermediate with substrate; via pyruvic acid
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Thymidylate synthase/dCMP hydroxymethylase
TRAP C4-dicarboxylate transport system permease DctM subunit
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Glycosyl transferase family 3 N-terminal
Exonuclease VII large subunit C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Gamma-glutamylcyclotransferase AIG2-like
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Quercetin 2,3-dioxygenase C-terminal cupin
Activator of Hsp90 ATPase homologue 1-like C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Autotransporter domain-containing protein
TonB-dependent receptor-like beta-barrel
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Putative regulatory protein FmdB Zinc ribbon
Cysteine sulfenic acid (-SOH) intermediate
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Carbamoyl-phosphate synthase small subunit N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Reversibly protonated during proton transport
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Release factor glutamine methyltransferase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
RND efflux pump membrane fusion protein barrel-sandwich
Polymerase/histidinol phosphatase N-terminal
Integral membrane protein YccS N-terminal
DNA replication/recombination mediator RecO N-terminal
Heme-copper oxidase subunit III family profile
Solute-binding protein family 3/N-terminal
Polysaccharide biosynthesis protein CapD-like
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Type III secretion system flagellar brake protein YcgR PilZN
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Flagellar motor switch protein FliN-like C-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
Cation-transporting P-type ATPase N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Flavocytochrome c sulphide dehydrogenase flavin-binding
PHA accumulation regulator DNA-binding N-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Sodium/calcium exchanger membrane region
Bacterial type II secretion system protein E
Cytochrome b561 bacterial/Ni-hydrogenase
Glycosyltransferase subfamily 4-like N-terminal
ABC-type glycine betaine transport system substrate-binding
RNA binding; important for wobble base 34 recognition
Could be important to modulate the pK values of the two catalytic cysteine residues
Choloylglycine hydrolase/NAAA C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
CNP1-like uncharacterized domain-containing protein
Lysidine-tRNA(Ile) synthetase C-terminal
Glycine zipper 2TM domain-containing protein
Nitrite/Sulfite reductase ferredoxin-like
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
CagE TrbE VirB component of type IV transporter system central
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Mandelate racemase/muconate lactonizing enzyme C-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Survival protein SurE-like phosphatase/nucleotidase
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Enterochelin esterase N-terminal domain-containing protein
Molybdopterin cofactor biosynthesis C (MoaC)
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Alanyl-transfer RNA synthetases family profile
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Electron transfer flavoprotein alpha/beta-subunit N-terminal
DNA-directed DNA polymerase family A palm
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Pyruvate dehydrogenase E1 component middle
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
BAAT/Acyl-CoA thioester hydrolase C-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
Anthranilate synthase component I N-terminal
Important for interaction with partner proteins
Chromosomal replication initiator DnaA C-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Small ribosomal subunit protein uS4 N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Prepilin type IV endopeptidase peptidase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Ionotropic glutamate receptor C-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
SsuA/THI5-like domain-containing protein
Glucose-methanol-choline oxidoreductase C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Restriction endonuclease type I HsdR N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Electron transfer via tryptophanyl radical
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Calcineurin-like phosphoesterase domain-containing protein
Peptide methionine sulphoxide reductase MsrA
Prokaryotic-type class I peptide chain release factors
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Surface antigen domain-containing protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Type IV secretion system coupling protein TraD DNA-binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Phosphotransferase system enzyme I N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Glycine zipper domain-containing protein
ABC transporter substrate-binding protein PnrA-like
Phosphatidic acid phosphatase type 2/haloperoxidase
Membrane insertase YidC/Oxa/ALB C-terminal
Plays an important role in discriminating NADH against NADPH
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Proline utilization A proline dehydrogenase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Pilus formation protein N-terminal domain-containing protein
Type II secretion system protein GspG C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Aspartate/homoserine dehydrogenase NAD-binding
Carboxypeptidase regulatory-like domain-containing protein
Pyridoxamine 5'-phosphate oxidase putative
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Outer membrane lipoprotein carrier protein LolA
CobB/CobQ-like glutamine amidotransferase
Contractile injection system tube protein N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
NIF system FeS cluster assembly NifU N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Essential for prephenate dehydratase activity
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
40-residue YVTN family beta-propeller repeat protein
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Shikimate dehydrogenase substrate binding N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Required for zinc-mediated homotetramerization and catalytic activity
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Glycine cleavage T-protein C-terminal barrel
Endoribonuclease L-PSP/chorismate mutase-like
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Aldehyde oxidase/xanthine dehydrogenase first molybdopterin binding
Aldehyde oxidase/xanthine dehydrogenase second molybdopterin binding
Large ribosomal subunit protein uL15/eL18
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Guanylate kinase/L-type calcium channel beta subunit
Yop protein translocation protein D periplasmic
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Lytic transglycosylase superhelical linker
Chromosomal replication initiator protein DnaA
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Flagellar assembly protein FliH/Type III secretion system HrpE
Moybdenum cofactor oxidoreductase dimerisation
Secretion system X translation initiation factor
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Thiol:disulfide interchange protein DsbA
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Positions MEP for the nucleophilic attack
Histidine-specific methyltransferase SAM-dependent
HicB-like antitoxin of toxin-antitoxin system
Alpha-D-phosphohexomutase alpha/beta/alpha
Gp5/Type VI secretion system Vgr protein OB-fold
Sodium symporter small subunit predicted
Type III secretion system effector delivery regulator TyeA
Mannose-6-phosphate isomerase type II C-terminal
Alpha-glycerophosphate oxidase C-terminal
Translation elongation factor P/YeiP central
Outer membrane protein assembly factor BamD
RNA 2-O ribose methyltransferase substrate binding
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
NADH-rubredoxin oxidoreductase C-terminal
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Regulator of nucleoside diphosphate kinase N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Soluble ligand binding domain-containing protein
Outer membrane protein assembly factor BamC
Outer-membrane lipoprotein carrier protein
DNA polymerase III subunit delta C-terminal
Adaptive response protein AidB N-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Phosphoadenosine phosphosulphate reductase
Oxidoreductase molybdopterin-binding domain-containing protein
Tc toxin complex TcA C-terminal TcB-binding
Pseudouridine synthase I TruA alpha/beta
Glucosamine/galactosamine-6-phosphate isomerase
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
NADH:ubiquinone oxidoreductase 30kDa subunit
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Large ribosomal subunit protein uL2 C-terminal