Removed in mature form; by autocatalysis
Bacterial type II secretion system protein E
Thiamine pyrophosphate enzyme TPP-binding
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
TATA box binding protein associated factor (TAF) histone-like fold
Hypoxanthine/guanine phosphoribosyltransferase
Major facilitator superfamily (MFS) profile
Pyrroline-5-carboxylate reductase catalytic N-terminal
Dihydroneopterin aldolase MtpD C-terminal
N(4)-bis(aminopropyl)spermidine synthase C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Glycosyltransferase subfamily 4-like N-terminal
Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop
Translation elongation factor IF5A C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
DNA-directed RNA polymerase RBP11-like dimerisation
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Na+/H+ antiporter MnhB subunit-related protein
SAM-dependent methyltransferase TRM5/TYW2-type
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Prepilin type IV endopeptidase peptidase
H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Interchain (with Cys-217); in linked form
Interchain (with Cys-51); in linked form
Glycosyl transferase family 3 N-terminal
Peptidase A24A-predicted C-terminal archaea
Polysaccharide biosynthesis protein C-terminal
Glutamate synthase alpha subunit C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Late embryogenesis abundant protein LEA-2 subgroup
Aminoacyl-tRNA synthetase class I anticodon-binding
Plays an important role in substrate specificity
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Schiff-base intermediate with dihydroxyacetone-P
Tetrahydromethanopterin S-methyltransferase subunit A
Pyrimidine nucleoside phosphorylase C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal
RNase L inhibitor RLI-like possible metal-binding
N6 adenine-specific DNA methyltransferase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Cation-transporting P-type ATPase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Schiff-base intermediate with D-ribose 5-phosphate
Phosphatidic acid phosphatase type 2/haloperoxidase
Damage-control phosphatase ARMT1-like metal-binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Non-canonical purine NTP phosphatase/PRRC1
Dinitrogenase iron-molybdenum cofactor biosynthesis
Polymerase/histidinol phosphatase N-terminal
Acetylserotonin O-methyltransferase dimerisation
Tryptophan synthase beta chain-like PALP
Type ISP restriction-modification enzyme LLaBIII C-terminal specificity
Gamma-glutamylcyclotransferase AIG2-like
Type I restriction enzyme R protein N-terminal
Type I restriction modification DNA specificity
DNA polymerase II large subunit DP2 N-terminal
6-hydroxymethylpterin diphosphokinase MptE-like
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Phosphoadenosine phosphosulphate reductase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Methyl-coenzyme M reductase alpha subunit C-terminal
Methyl-coenzyme M reductase alpha subunit N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Glycoside hydrolase family 57 N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Large ribosomal subunit protein uL15/eL18
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
May act as a substrate filter by repelling compounds with a negatively charged alpha-carboxylate
60S ribosome subunit biogenesis protein NIP7 pre-PUA
O-(5'-phospho-DNA)-tyrosine intermediate
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Transcription factor CBF/NF-Y/archaeal histone
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Tetrahydromethanopterin S-methyltransferase F subunit
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Alpha-D-phosphohexomutase alpha/beta/alpha
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase
RNA polymerase subunit H/Rpb5 C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Transcription factor NikR nickel binding C-terminal
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Large ribosomal subunit protein uL2 C-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Survival protein SurE-like phosphatase/nucleotidase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Aldehyde ferredoxin oxidoreductase N-terminal
Important for guanine/8-oxoguanine distinction
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Thymidylate synthase/dCMP hydroxymethylase
Pyridoxamine 5'-phosphate oxidase putative
Small ribosomal subunit protein uS15 N-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Phosphoribosylformylglycinamidine synthase linker
Alanyl-transfer RNA synthetases family profile
Pyruvate phosphate dikinase AMP/ATP-binding
DNA-directed RNA polymerase subunit 2 hybrid-binding
Pseudouridine synthase I TruA alpha/beta
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Large ribosomal subunit protein uL10-like insertion
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Inosine monophosphate cyclohydrolase-like
Ribosomal RNA adenine methylase transferase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Pyruvoyl-dependent arginine decarboxylase subunit alpha
Pyruvoyl-dependent arginine decarboxylase subunit beta
Glycosyl transferase family 28 C-terminal
Small zinc finger protein HVO-2753-like zinc-binding pocket
Spo11/DNA topoisomerase VI subunit A N-terminal
Methyl-coenzyme M reductase beta subunit C-terminal
Methyl-coenzyme M reductase beta subunit N-terminal
Protein G-related albumin-binding (GA) module
Small ribosomal subunit protein uS4 N-terminal
RNA 3'-terminal phosphate cyclase insert
Bacterial bifunctional deaminase-reductase C-terminal